Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_1239
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Entry
ERDMAN_1239 CDS
T02526
Name
(GenBank) cholesterol dehydrogenase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00984
Steroid degradation
mtn01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
ERDMAN_1239
Enzymes [BR:
mtn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
ERDMAN_1239
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
ERDMAN_1239
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Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
NAD_binding_4
RmlD_sub_bind
Polysacc_synt_2
KR
NmrA
adh_short
Motif
Other DBs
NCBI-ProteinID:
BAL65042
UniProt:
A0A0H3L7S7
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Position
complement(1231360..1232460)
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AA seq
366 aa
AA seq
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MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI
TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ
RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR
PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT
APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP
LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT
AATVKP
NT seq
1101 nt
NT seq
+upstream
nt +downstream
nt
atgggtgatgcatcgctgacaaccgagctcggccgcgttctggtcaccggcggcgcgggc
ttcgtgggcgccaacctggtgaccaccttgctggaccgcgggcactgggtgcgttccttc
gaccgcgcgccgtcgctgttgcctgcgcatccgcaactggaggtgctgcaaggggacatc
accgacgcggacgtctgcgccgcggccgtggacggcatcgacacgatcttccacaccgca
gcgatcatcgagctgatgggcggcgcgtcggtcaccgacgagtaccgccaacgtagcttt
gcggtcaacgtcggcggcaccgagaacctgctgcacgccggccagcgggccggggtgcag
cggttcgtctacacgtcatccaacagtgtggtgatgggcggccagaacatcgccggcggt
gacgagacgctgccctataccgaccggttcaacgacctctacaccgagaccaaggtggtt
gccgagcgattcgtgttggcccagaacggtgtcgacggcatgctgacgtgcgcgatccgg
cccagcggcatctggggaaacggcgatcagacgatgttccgcaagctgttcgaaagtgtg
ctcaagggccacgtcaaggtgctggtcgggcgcaagtcggcccggctggataactcttac
gtgcacaacctgattcacggtttcatcttggccgctgcccatctggtgccggacggcaca
gcgcccgggcaggcttacttcatcaacgacgcagagccgatcaatatgttcgagttcgct
cggccggtgctcgaggcgtgcgggcagcgctggccgaagatgcggatttccggccccgcg
gtccgctgggtaatgacggggtggcagcggctgcacttccggttcggattccccgcgccg
ctgctcgagccgctggccgtcgaacgactgtacctggacaactacttttcgatcgctaag
gcacgccgcgacctgggctatgagccgctgttcaccacccagcaggcgctgaccgaatgc
ctgccgtactacgtgagtctgtttgagcagatgaagaacgaggcccgggcggaaaaaacg
gccgccacagtcaagccgtag
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