Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_2747
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Entry
ERDMAN_2747 CDS
T02526
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component alphasubunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00280
Valine, leucine and isoleucine degradation
mtn00640
Propanoate metabolism
mtn00785
Lipoic acid metabolism
mtn01100
Metabolic pathways
mtn01110
Biosynthesis of secondary metabolites
mtn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ERDMAN_2747 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ERDMAN_2747 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ERDMAN_2747 (pdhA)
Enzymes [BR:
mtn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
ERDMAN_2747 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
MCD
Motif
Other DBs
NCBI-ProteinID:
BAL66533
UniProt:
A0A0H3LBY0
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Position
complement(2798580..2799653)
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AA seq
357 aa
AA seq
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MLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL
ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF
TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT
TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA
RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL
EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgttgatgtctgtcgatcttgagccggtgcaactcgtcggcccggacggtacgccgacg
gccgaacgccgctaccaccgtgaccttcctgaggaaacgctgcgttggctctacgagatg
atggtggtcacccgcgagctggataccgaattcgtcaatctgcagcgccagggggagctg
gcgttgtacacgccctgtcgcgggcaggaagccgcgcaggtgggtgcggcggcttgccta
cgcaaaaccgactggttgttcccccaataccgagaattgggcgtctacctagtgcgtggc
atcccgcctggacatgttggggtcgcgtggcgtggaacctggcacggcgggctgcaattc
accacgaagtgctgtgcaccgatgtcggttcccatcggcacccagaccttgcacgcggtg
ggcgcggcgatggccgcgcaacgcctggacgaggactccgtgacggtggcctttctgggc
gacggcgccaccagcgagggcgacgtacatgaggcgctcaatttcgcggcggtgttcacc
acaccgtgcgtgttctacgtgcagaacaaccagtgggcaatctcgatgccggtatccagg
cagaccgccgcaccatctatcgcgcacaaggcgattggctacgggatgccaggcatccgg
gtggacggcaacgacgtgctggcatgctatgcggtgatggccgaagctgccgctcgggct
cgggccggcgacggtccaacgctgatcgaggcggtcacttaccgtcttggtccgcacacc
accgccgatgatccaacccggtaccgcagccaggaggaggtggaccgctgggcgacgctg
gacccgattccgcgctatcgcacttacttacaagatcagggcctgtggtcgcaacgcctc
gaggaacaggtgacggctcgggcaaaacacgtgcggtccgagctacgcgacgcggtcttt
gatgcgcctgacttcgacgtcgatgaggtgttcaccacggtgtacgccgaaatcacaccc
gggttgcaggcgcagcgcgaacagctgcgtgccgaactggcgcggactgactga
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