Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_3145
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Entry
ERDMAN_3145 CDS
T02526
Symbol
ispG
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphatesynthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00900
Terpenoid backbone biosynthesis
mtn01100
Metabolic pathways
mtn01110
Biosynthesis of secondary metabolites
Module
mtn_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
ERDMAN_3145 (ispG)
Enzymes [BR:
mtn01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
ERDMAN_3145 (ispG)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
ERDMAN_3145 (ispG)
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Motif
Pfam:
GcpE
MR_MLE_C
zf-RING_7
Motif
Other DBs
NCBI-ProteinID:
BAL66924
UniProt:
A0A0H3LCX2
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Position
complement(3167939..3169084)
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AA seq
381 aa
AA seq
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MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD
IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG
RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI
KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI
RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV
PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA
AEMGEQDPGATPSGSPIVTVS
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgccgcagcccccggcacccacgctcgctccccggcgcgccacccgtcagctgatggtc
ggcaacgtcggcgtgggcagtgaccatccggtctcggtgcaatcgatgtgcaccaccaaa
acccacgacgtcaactcgacattgcaacaaatcgccgagctgaccgcggccggatgcgac
atcgtgcgggtggcctgcccgcgccaggaggacgccgacgcgctggccgagatcgcccgg
cacagccagatcccggtagtcgcggacatacatttccagccgcgctacatattcgccgcc
atcgacgctggatgtgccgcggtgcgggtcaacccgggcaacatcaaggagtttgacggc
cgggtgggtgaggtcgccaaggcggcgggtgcggccgggatcccgatccgaatcggtgtc
aacgccggttcgctggacaaacggttcatggagaagtatggcaaagccacgcccgaggcg
ctggttgagtcggcgctgtgggaggcttcgcttttcgaggagcatggcttcggtgacatc
aagatcagcgtcaagcacaacgacccggtggtgatggtcgccgcctacgagctgcttgct
gcacggtgcgactacccactgcacctcggtgtcaccgaggccggccctgctttccagggc
accatcaagtccgcggttgccttcggcgcgttgctgtcgcggggcataggcgacaccatc
cgggtgtcgttgtcggccccgccggtcgaggaagtcaaggtgggcaatcaggttctcgag
tcgttgaacctgcggccgcgttcgctcgagatcgtgtcttgcccgtcgtgcggtcgcgcg
caagtcgacgtctacaccctggccaacgaggtaaccgccggcctggatggtctcgatgtg
ccgttgcgggtggccgtgatggggtgtgtcgtcaatggtccgggtgaagcacgtgaggcc
gacctgggcgtggcgtccggcaacggcaaaggtcagatctttgtacggggcgaagtgatc
aagaccgtgcccgaagcacagatcgtcgagacgctgatcgaggaggcgatgcggctggcc
gccgaaatgggcgagcaagatccgggcgcgacaccgagcggttcgcctattgtgaccgta
agctga
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