Mycobacterium tuberculosis H37Rv: Rv1391
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Entry
Rv1391 CDS
T00015
Symbol
dfp
Name
(RefSeq) bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase
KO
K13038
phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:
4.1.1.36
6.3.2.5
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00770
Pantothenate and CoA biosynthesis
mtu01100
Metabolic pathways
mtu01240
Biosynthesis of cofactors
Module
mtu_M00120
Coenzyme A biosynthesis, pantothenate => CoA
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Rv1391 (dfp)
Enzymes [BR:
mtu01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.36 phosphopantothenoylcysteine decarboxylase
Rv1391 (dfp)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.5 phosphopantothenate---cysteine ligase (CTP)
Rv1391 (dfp)
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Gene cluster
GFIT
Motif
Pfam:
DFP
Flavoprotein
YjeF_N
Motif
Other DBs
NCBI-GeneID:
886749
NCBI-ProteinID:
NP_215907
TubercuList:
Rv1391
UniProt:
P9WNZ1
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Position
1565441..1566697
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AA seq
418 aa
AA seq
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MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSG
EPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVL
FAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLL
LERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIA
GHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGV
EGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGC
DLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAIVTFLAGCSS
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
gtggtggaccataaacggatccccaagcaggtaatagtcggtgtctccgggggcatcgcc
gcctacaaggcgtgcacggttgttcgtcaactcaccgaggccagtcatcgcgtccgagtc
attcccaccgaatccgccctgcgcttcgtcggtgccgcgaccttcgaggcgctctccggt
gagccggtgtgcaccgacgttttcgccgacgttccggcggtcccgcatgttcacctcggc
cagcaggccgatctggtcgtagtggcgccggccaccgccgacctgctggcccgcgcggcg
gccggtcgagccgacgatctgctgaccgcgacgctgctgacggcgcggtgtccggtgctg
ttcgcgccggcgatgcacaccgagatgtggttgcatccggccaccgtcgacaacgtggcc
acgctgcgccgccgcggcgcggtggtgctcgagcccgcgacaggacggcttaccggcgcc
gacagcggggccggccgactgcccgaggcggaggagatcaccaccctcgcccagctgctg
ctggagcggcacgacgccctgccctacgatctcgcggggcgaaagctgctggttaccgcc
ggtggcacacgcgagccgatcgatccggtgcgctttatcggcaaccgcagctccggcaag
cagggctatgcggtggcgcgggtggccgcccagcgcggcgccgacgttactttgatcgct
gggcataccgcagggctcgtcgatcccgccggcgtcgaggtggtgcacgtcagctcggcc
cagcaactcgccgacgcggtgtccaagcacgctccgaccgccgacgtattggtgatggcg
gcggccgtcgccgacttccggcccgcgcaggttgccaccgccaaaatcaagaaaggcgtc
gaaggcccaccgaccatcgagctgctgcgcaacgacgacgtgctggccggggtggtgcgg
gcccgagcccatggacaactgcccaacatgcgggccattgtgggcttcgcagccgagacc
ggcgacgccaatggcgacgtgctctttcatgcccgagctaaactgcgacgcaaaggctgc
gatctgttagtcgtcaatgccgtcggcgaaggcagggcctttgaggtagacagcaacgac
ggctggctactggcgtccgatggtaccgagtcggcattgcagcacggctccaagacactg
atggcgagccgtatcgttgatgcaatcgtcacgttcctggcaggctgtagcagctaa
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