Mycobacterium tuberculosis H37Rv: Rv2495c
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Entry
Rv2495c CDS
T00015
Symbol
bkdC
Name
(RefSeq) branched-chain keto acid dehydrogenase E2 component
KO
K09699
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:
2.3.1.168
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00280
Valine, leucine and isoleucine degradation
mtu00640
Propanoate metabolism
mtu00785
Lipoic acid metabolism
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
mtu01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Rv2495c (bkdC)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Rv2495c (bkdC)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Rv2495c (bkdC)
Enzymes [BR:
mtu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
Rv2495c (bkdC)
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Paralog
Gene cluster
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Motif
Pfam:
2-oxoacid_dh
Biotin_lipoyl
E3_binding
GCV_H
Ribosomal_L13
DUF6403
Motif
Other DBs
NCBI-GeneID:
888237
NCBI-ProteinID:
NP_217011
TubercuList:
Rv2495c
UniProt:
O06159
Structure
PDB
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All DBs
Position
complement(2808758..2809939)
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AA seq
393 aa
AA seq
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MSGEDSIRSFPVPDLGEGLQEVTVTCWSVAVGDDVEINQTLCSVETAKAEVEIPSPYAGR
IVELGGAEGDVLKVGAELVRIDTGPTAVAQPNGEGAVPTLVGYGADTAIETSRRTSRPLA
APVVRKLAKELAVDLAALQRGSGAGGVITRADVLAAARGGVGAGPDVRPVHGVHARMAEK
MTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTW
VDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLT
PAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTC
VFDHRVVDGAQVAQFMCELRDLIESPETALLDL
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
atgagcggtgaggacagcatcaggtctttcccggtgcccgacctcggcgagggactgcag
gaagtgacggtgacgtgttggagcgtcgccgtcggcgacgatgtggagatcaaccagacg
ctgtgttcggtggagaccgccaaggccgaggtcgaaatccccagcccgtatgccggccgg
atcgtcgagttaggcggcgccgaaggcgatgtgctcaaagtgggcgcggagctagttcgg
atcgacaccgggcccacggcagttgcgcagcctaacggtgaaggagcggtccccacgttg
gtcggctacggtgccgacaccgcgatcgaaaccagtagacggacaagccggccgctggcg
gcaccggtagtgcgcaagctggccaaagagttggcggtcgacctggccgcattgcagcgt
gggtcgggcgccggcggtgtgatcacccgggccgatgtgctggccgctgctcgaggcggc
gtcggagccgggccggacgtgcggccggtccacggcgtgcacgcgcggatggccgaaaaa
atgacgttgtcccacaaggagattccgaccgcaaaggccagcgttgaggtaatttgcgcc
gaactgctgcggctgcgcgaccggttcgtttcggcggcgcccgagattacaccgttcgcg
ctgacgctgcggctgctggttattgcattgaaacacaacgtaattctcaactcgacgtgg
gtcgactcgggcgaaggcccgcaagtacacgtgcatcgcggtgtgcatctggggttcggc
gcggccactgagcgtggattgctggtgccggtggtgaccgacgcccaggacaagaacacc
cgcgaacttgcctcccgcgtagcggaattaatcaccggcgcacgtgaaggcactctcaca
cccgcggagctgcgcggttcgacgttcacggtgtcgaacttcggggcgctgggagtcgac
gacggcgtgccggtgatcaaccatcccgaagcggcgatcctgggtctgggggcgatcaag
ccgcgcccggtggtcgtcggcggcgaggttgtcgcacggccgacgatgacgttgacttgt
gtgttcgaccaccgcgttgtcgatggtgctcaggtggcccagttcatgtgtgagctgcgg
gatctgatcgagtcgccggagaccgcgctgttggatctgtag
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