Mycobacterium tuberculosis Haarlem/NITR202: I917_09870
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Entry
I917_09870 CDS
T02654
Name
(GenBank) bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase
KO
K13038
phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:
4.1.1.36
6.3.2.5
]
Organism
mtuh
Mycobacterium tuberculosis Haarlem/NITR202
Pathway
mtuh00770
Pantothenate and CoA biosynthesis
mtuh01100
Metabolic pathways
mtuh01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mtuh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
I917_09870
Enzymes [BR:
mtuh01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.36 phosphopantothenoylcysteine decarboxylase
I917_09870
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.5 phosphopantothenate---cysteine ligase (CTP)
I917_09870
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Gene cluster
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Motif
Pfam:
DFP
Flavoprotein
YjeF_N
Motif
Other DBs
NCBI-ProteinID:
AGL23080
UniProt:
R4LX59
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All DBs
Position
1567519..1568739
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AA seq
406 aa
AA seq
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MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSG
EPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVL
FAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLL
LERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIA
GHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGV
EGPPTIELLRNDDVLAGVVRXRXXGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGC
DLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHXSKDTXGEPYR
NT seq
1221 nt
NT seq
+upstream
nt +downstream
nt
gtggtggaccataaacggatccccaagcaggtaatagtcggtgtctccgggggcatcgcc
gcctacaaggcgtgcacggttgttcgtcaactcaccgaggccagtcatcgcgtccgagtc
attcccaccgaatccgccctgcgcttcgtcggtgccgcgaccttcgaggcgctctccggt
gagccggtgtgcaccgacgttttcgccgacgttccggcggtcccgcatgttcacctcggc
cagcaggccgatctggtcgtagtggcgccggccaccgccgacctgctggcccgcgcggcg
gccggtcgagccgacgatctgctgaccgcgacgctgctgacggcgcggtgtccggtgctg
ttcgcgccggcgatgcacaccgagatgtggttgcatccggccaccgtcgacaacgtggcc
acgctgcgccgccgcggcgcggtggtgctcgagcccgcgacaggacggcttaccggcgcc
gacagcggggccggccgactgcccgaggcggaggagatcaccaccctcgcccagctgctg
ctggagcggcacgacgccctgccctacgatctcgcggggcgaaagctgctggttaccgcc
ggtggcacacgcgagccgatcgatccggtgcgctttatcggcaaccgcagctccggcaag
cagggctatgcggtggcgcgggtggccgcccagcgcggcgccgacgttactttgatcgct
gggcataccgcagggctcgtcgatcccgccggcgtcgaggtggtgcacgtcagctcggcc
cagcaactcgccgacgcggtgtccaagcacgctccgaccgccgacgtattggtgatggcg
gcggccgtcgccgacttccggcccgcgcaggttgccaccgccaaaatcaagaaaggcgtc
gaaggcccaccgaccatcgagctgctgcgcaacgacgacgtgctggccggggtggtgcgg
kcccgakcmcrtggacaactgcccaacatgcgggccattgtgggcttcgcagccgagacc
ggcgacgccaatggcgacgtgctctttcatgcccgagctaaactgcgacgcaaaggctgc
gatctgttagtcgtcaatgccgtcggcgaaggcagggcctttgaggtagacagcaacgac
ggctggctactggcgtccgatggkaccgagtcggcattgcagcacgsctccaaagacack
gakggsgagccgtatcgttga
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