Meriones unguiculatus (Mongolian gerbil): 110553509
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Entry
110553509 CDS
T05884
Symbol
Hsd11b1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00140
Steroid hormone biosynthesis
mun00980
Metabolism of xenobiotics by cytochrome P450
mun01100
Metabolic pathways
mun05204
Chemical carcinogenesis - DNA adducts
Module
mun_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
110553509 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
110553509 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
110553509 (Hsd11b1)
Enzymes [BR:
mun01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
110553509 (Hsd11b1)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
FMO-like
Pyr_redox_2
Shikimate_DH
Methyltransf_25
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
110553509
NCBI-ProteinID:
XP_021501134
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All DBs
Position
11:complement(111439161..111464303)
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AA seq
291 aa
AA seq
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MAFMKIYLLPLLVLFLGYYYSTDEEFRPEMLQGKKVIVTGASKGIGREMAYLLSKMGAHV
VVTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAEQFVVKAGKLMGGLDMLIINHI
NIDHMSFFHGNVHSVRKTMEVNFLSYVVLSVAALPMLKQSNGSIAVVSSMAGKMTLPMTA
SYSASKFALDGFFSTIRKEYVMTKVNVSITLCILGLIDTETAMREVSGKINLPAAPKEGC
ALEIIKGTALRKDEVYYDASSWKPILLRNPGRKIMEFLTYRKYNLENIVNN
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggcatttatgaaaatatacctcctcccccttctggtgctcttcttgggctactactat
tctacagatgaagagttcaggccggaaatgctccaaggcaagaaagtgatcgtcacgggg
gccagcaaagggattggaagagaaatggcatatctcctgtcaaaaatgggcgcccacgtg
gtggtgactgcgagatcggaggaaggtctgcagaaggttgtgtctcgatgccttgaactt
ggagcagcctctgctcactacattgctggcactatggaagacatggcatttgcagagcaa
tttgttgtcaaagcaggaaagctcatgggtggactggacatgctcattatcaaccacatc
aacatcgaccatatgtctttttttcatgggaatgtccacagtgtgaggaaaaccatggag
gtcaacttcctcagctacgtggtcctgagcgtcgccgccttgcccatgctgaagcagagc
aacggcagcatcgccgtggtctcctccatggctgggaaaatgacgctgcccatgactgcg
tcctactctgcaagcaagtttgctctggatgggttcttttcaaccattaggaaagaatac
gtaatgaccaaggtcaacgtgtctatcacgctctgtatccttggcctcatagacacagaa
acagccatgagggaggtctctgggaaaataaacctcccagctgctcccaaggagggctgc
gccctggagatcatcaaagggacagctctgcgcaaagacgaggtgtactatgatgcctcc
agctggaagcccatcctgcttaggaacccaggaaggaagatcatggaatttcttacctat
aggaaatataaccttgagaacattgtaaacaactag
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