Mycolicibacterium vanbaalenii: Mvan_4477
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Entry
Mvan_4477 CDS
T00449
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mva
Mycolicibacterium vanbaalenii
Pathway
mva00020
Citrate cycle (TCA cycle)
mva00630
Glyoxylate and dicarboxylate metabolism
mva00785
Lipoic acid metabolism
mva01100
Metabolic pathways
mva01110
Biosynthesis of secondary metabolites
mva01120
Microbial metabolism in diverse environments
mva01200
Carbon metabolism
mva01210
2-Oxocarboxylic acid metabolism
Module
mva_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mva_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mva00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Mvan_4477
00630 Glyoxylate and dicarboxylate metabolism
Mvan_4477
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mvan_4477
Enzymes [BR:
mva01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Mvan_4477
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Mvan_4477
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Mvan_4477
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Mvan_4477
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ABM15252
UniProt:
A1TDK2
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All DBs
Position
4810214..4814002
Genome browser
AA seq
1262 aa
AA seq
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MAGCRGVLARSEELRRKAAVNSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHEFLVDYSP
EPTNDAPAGNGKPAAAPTAPPEPASAPAPKPASTNGGAPPAKADTSTTRAPEKKPEEKTS
PAPKAKTAAPAGVSDDDETQVLRGAAAAVVKNMSASLDVPTATSVRAIPAKAMIDNRIVI
NNHLKRTRGGKISFTHLLGYAIVQAVKKFPNMNRHFAEIDGKPVAVTPAHTNLGLAIDLP
GKDGKRSLVVAAIKNCETMHFGQFIAAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGT
VHSVPRLMKGQGAIVGAGAMEYPAEFQGASEERIAELGVGKLMTLTSTYDHRIIQGAESG
DFLRTIHTLLLDDEFYDEIFRELGIPHEPVRWRIDNPDSIEDKNARVIELIAAYRNRGHL
MADIDPLRLDKTRFRSHPDLDVNTHGLTLWDLDREFKVNGFAGKTHKKLRDILGLLRDAY
CRHIGVEYTHILEPEQQQWLQERIEVKHEKPTVAEQKYILSKLNAAEAFETFLQTKYVGQ
KRFSLEGAETVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEG
NLNPSQAHGSGDVKYHLGANGTYIQMFGDNDIDVSLVANPSHLEAVDPVLEGLVRAKQDI
LDKGNGPDGFTVVPMMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTS
PYDSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVAKLAVDFRQKFKKDVVIDMLCYRRR
GHNEGDDPSMTQPTMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFN
EVRELEKHAIAPSSSVESDQMVPAGMSTAVDKSLLARIGDAHLGYPDDFNVHPRVKPVLE
KRREMAYEGKVDWAFAELLALGTFLAEGKTIRFTGQDTRRGTFTQRHSVIIDRQTGREFT
PLDLLTVDSDGNPTGGKFMAYDSALSEFAAVGFEYGYSVGNPNALVLWEAQFGDFVNGAQ
SIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLLLWAEGSMTIAMPSTP
ANYFHLLRRHGLDGIHRPLIVFTPKSMLRNKAAVSDLKDFTEMKFRSVLEEPTYTEGTGD
RSKAKRILLTSGKLYYELAARKSKEGRDDVAILRLEQLAPLPKRRLAATLDEYPNAEQYF
WVQEEPANQGAWPTLGLTLPEVLPEKLAGIKRISRRAMSAPSSGSSKVHAVEQQEIIDEA
FG
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
gtggccggctgccgcggggtgctggcccgaagcgaagaattgaggcgaaaagcagccgtg
aactcaccttcaccattcggtcagaacgagtggttggtcgaagagatgtaccgcaagttc
cgcgaggatccgtcgtcggtcgacccgagttggcacgagttcctcgtcgactactccccc
gaacccaccaatgacgcccccgcaggcaacggcaagccggccgctgcgcccaccgcaccg
ccggaacccgcttcggctccggcccccaaacccgcgagcaccaacggtggcgccccgccc
gccaaggccgacacgtcgaccacccgggcccccgagaagaagccggaggagaaaacctcg
ccggcacccaaggccaagaccgccgcaccggccggcgtgtccgacgacgacgagacccag
gtgctgcgcggcgccgcggcggccgtggtcaagaacatgtccgcctcgctggacgtgccg
accgcgacgagcgtgcgcgccatcccggccaaggcgatgatcgacaaccggatcgtcatc
aacaaccacctcaagcgcacccggggcggcaagatctcgttcacccacctgctggggtac
gcgatcgtgcaggcggtcaagaagttccccaacatgaaccggcacttcgccgagatcgac
ggcaagccggttgcggtcacaccagcccacacgaacctgggcctggcgatcgacctgccc
ggcaaggacgggaagcgctcgctggtggtcgccgcgatcaagaactgcgagaccatgcac
ttcggtcagttcatcgcggcctacgaggacatcgtgcgtcgcgcccgcgacggcaaactg
accgccgaagactttgcgggcgtgacgatttcgctgaccaaccccggcaccatcggcacc
gtccactcggtaccgcggctgatgaagggccagggcgcgatcgtcggtgccggcgcgatg
gagtacccggcggagttccagggcgccagcgaggagcgcatcgccgagctcggcgtgggc
aagctgatgaccctgacgtcgacctacgaccaccgcatcatccagggcgcggagtccggc
gacttcctgcgcacgatccacaccctgctgctcgatgacgagttctacgacgagatcttc
cgcgagctgggcatcccccacgagccggtgcgctggcgcatcgacaacccggattccatc
gaggacaagaacgcccgcgtcatcgagctcatcgcggcataccgcaaccgtggccacctg
atggcagacatcgatccgctgcggctggacaagacccgcttccgcagccatcccgacctc
gacgtcaacacccacgggctgacgctgtgggacctcgaccgcgagttcaaggtcaacggt
ttcgccggcaagacccacaagaagctgcgcgacatcctgggtctgctgcgcgatgcctac
tgccgccacatcggcgtggagtacacgcacatcctcgagcccgagcaacagcagtggctg
caggagcgcatcgaggtcaagcacgagaagcccacggtcgccgagcagaagtacatcttg
agcaagctcaacgccgccgaggcgttcgagaccttcctgcagaccaaatacgttgggcag
aaacggttctcactcgaaggagcggagaccgtcatcccgatgatggacgccgcgatcgac
cagtgcgccgaacacggcctcgatgaggtcgtcatcgggatgccgcaccgcggccggctc
aacgtgctggccaacatcgtcggcaagccgtactcgcagatcttcaccgagttcgagggc
aacctgaacccgtcgcaggcccacggctccggtgacgtgaagtaccacctgggcgccaac
ggcacctacatccagatgttcggcgacaacgacatcgacgtgtcgctggtcgccaacccc
agccacctcgaggccgtcgacccggtgctggaaggactggtccgcgccaagcaggacatc
ctggacaagggcaacggccccgacggcttcaccgtcgtgccgatgatgctgcacggcgac
gccgcgttcgccggacagggtgtggtcgccgaaacactgaacctggcgctgctgcgcggc
taccgcaccggcgggacgatccacatcatcgtcaacaaccagatcggcttcaccacgtcc
ccgtacgactcgcggtcgtcggagtactgcaccgacgtcgccaagatgatcggcgccccg
atcttccacgtcaacggcgacgaccccgaagcctgcgtctgggtggccaagctggccgtc
gacttccggcagaagttcaagaaggacgtcgtcatcgacatgctgtgctaccgcaggcgc
ggccacaacgagggcgacgacccgtcgatgacgcagccgaccatgtacgacgtcatcgac
accaagcgcggcgtgcgcaagagctacaccgaggcgctgatcggtcgcggcgacatctcg
atgaaggaagccgaagacgcgctgcgcgactaccagggccagctcgagcgggtgttcaac
gaggtacgcgagctggagaagcacgcgatcgcacccagttcgtcggtggagtccgaccag
atggtccctgccggcatgagcaccgcggtcgacaagtcgctgctggcccgcatcggtgac
gcgcacctgggctaccccgacgacttcaacgtccacccgcgcgtcaagccggtgctggag
aagcgccgagagatggcctacgagggcaaggtcgactgggccttcgccgaactgctggcc
ctcggcacgttcctcgccgaaggcaagacgatccgcttcaccgggcaggacaccagacgc
ggcacgttcacccagcggcattcggtgatcatcgaccgccagaccgggcgcgagttcacc
cccttggacctgctcaccgtcgactccgacggcaacccgaccggcggcaagttcatggca
tacgactcggcgctgtcggagttcgcggcggtcggcttcgagtacggctactcggtcggc
aacccgaacgcattggtgttgtgggaggcgcagttcggtgacttcgtcaacggcgcgcag
tcgatcatcgacgagttcatcagctccggcgaggccaagtggggccagctctccgacgtg
gtgctgctgctgccgcacggccacgagggccagggcccggaccacacgtcgggccgcatc
gagcggttcctgctgttgtgggccgagggctcgatgaccatcgcgatgccgtccacgccg
gcgaactacttccatctgctgcgccgccacgggctcgacgggatccaccggccgctgatc
gtgttcacgccgaagtcgatgctgcgcaacaaggctgcggtcagcgatctgaaggacttc
accgagatgaagttccggtcggtgctggaggagcccacctacaccgagggcaccggagac
cggagcaaggccaagcggatcctgctgaccagcggcaagctgtactacgagctggcggcg
cgcaagagcaaggagggtcgcgacgatgtggcgatcctgcggctggaacagttggccccg
ctgccgaagcgtcggctcgccgcgacgctggacgagtacccgaacgccgaacagtacttc
tgggtgcaggaggagccggcgaaccagggggcgtggccgacgctggggttgacgttgccc
gaagtgcttccggagaagcttgcgggcatcaagcggatctcgcggcgcgcgatgtcggcc
ccgtcgtctggctcgtcgaaggtgcacgccgtcgagcagcaggagatcatcgacgaagcc
ttcggctga
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