Myotis brandtii (Brandt's bat): 102253056 Help Entry 102253056         CDS       T02920                                  Symbol JAK2 Name (RefSeq) Janus kinase 2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb01521   EGFR tyrosine kinase inhibitor resistance myb04062   Chemokine signaling pathway myb04148   Efferocytosis myb04151   PI3K-Akt signaling pathway myb04217   Necroptosis myb04550   Signaling pathways regulating pluripotency of stem cells myb04630   JAK-STAT signaling pathway myb04658   Th1 and Th2 cell differentiation myb04659   Th17 cell differentiation myb04725   Cholinergic synapse myb04917   Prolactin signaling pathway myb04920   Adipocytokine signaling pathway myb04933   AGE-RAGE signaling pathway in diabetic complications myb04935   Growth hormone synthesis, secretion and action myb05140   Leishmaniasis myb05145   Toxoplasmosis myb05152   Tuberculosis myb05161   Hepatitis B myb05164   Influenza A myb05167   Kaposi sarcoma-associated herpesvirus infection myb05168   Herpes simplex virus 1 infection myb05200   Pathways in cancer myb05207   Chemical carcinogenesis - receptor activation myb05235   PD-L1 expression and PD-1 checkpoint pathway in cancer myb05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102253056 (JAK2)    04151 PI3K-Akt signaling pathway     102253056 (JAK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     102253056 (JAK2)   09143 Cell growth and death    04217 Necroptosis     102253056 (JAK2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102253056 (JAK2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     102253056 (JAK2)    04659 Th17 cell differentiation     102253056 (JAK2)    04062 Chemokine signaling pathway     102253056 (JAK2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     102253056 (JAK2)    04917 Prolactin signaling pathway     102253056 (JAK2)    04935 Growth hormone synthesis, secretion and action     102253056 (JAK2)   09156 Nervous system    04725 Cholinergic synapse     102253056 (JAK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102253056 (JAK2)    05207 Chemical carcinogenesis - receptor activation     102253056 (JAK2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102253056 (JAK2)   09172 Infectious disease: viral    05161 Hepatitis B     102253056 (JAK2)    05164 Influenza A     102253056 (JAK2)    05168 Herpes simplex virus 1 infection     102253056 (JAK2)    05167 Kaposi sarcoma-associated herpesvirus infection     102253056 (JAK2)   09171 Infectious disease: bacterial    05152 Tuberculosis     102253056 (JAK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102253056 (JAK2)    05140 Leishmaniasis     102253056 (JAK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102253056 (JAK2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102253056 (JAK2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102253056 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myb01001]     102253056 (JAK2) Enzymes [BR:myb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102253056 (JAK2) Protein kinases [BR:myb01001]  Non-receptor tyrosine kinases   JAK family [OT]    102253056 (JAK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl SH2 Kdo ABC1 FERM_C_FAK1 RIO1 Kinase-like FERM_M Motif Other DBs NCBI-GeneID:  102253056 NCBI-ProteinID:  XP_005861389 LinkDB All DBs Position Un AA seq 1132 aa AA seqDB search MEMACLTMTEMEGTCTPPMHQNGDIPGITDSVKQIDPVLQVYLYHSLGKTEGDYLKFSTG EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNYVFHIDESTRHNVLYRIRFYF PYWYCSGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG MAVLDMMRIAKENDQTPLDVYSSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIEQF SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR GKHKESETLTEQDLQLYCDFPDIIDVSIKQASQEGSNESRIVTIHKQDGKNLEIELISLK EALSFVSLIDGYYRLTADAHHYLCKEVASPVVLENIQSNCHGPISMDFAISKLKKAGNQT GLYVLRCSPKEFNKYFLTFAVERDNVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNSVSDVPTSPTLQRHNNVNQMVFHKI RNEDLVFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA MHFLEEKNLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISVTVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRNLALRVDQIRDNIAG NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atggaaatggcttgcctcacaatgacagaaatggaaggaacatgcacacctcctatgcat cagaatggagatattcctggaattactgattctgtgaagcaaatagatccagtccttcag gtgtatctttatcattcccttgggaaaactgagggagattacctgaagttttcaactggg gaatatgttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctgtg tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccgcccaactat gtcttccatatagatgagtcaaccaggcacaatgtactctacagaataagattttacttt ccttactggtattgtagcggcagcaacagaacttatcggcatggaatatctcgaggtgct gaagctcctcttcttgatgactttgttatgtcttacctttttgctcagtggcggcatgat tttttgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg atggcagtgttagatatgatgagaatagccaaagaaaatgatcaaactccactcgacgtc tatagctctatcagctataagacattcttaccaaaatgtattcgagcaaagatccaagac tatcatattttgacaagaaagcgaataaggtaccgatttcgcagatttattgagcaattc agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggaaacataaagaaagtgaaacactgacagaacaggatttacagttatattgtgacttt cccgatattattgatgtcagtattaagcaggcaagccaagaaggctcaaatgaaagcaga attgtaactatccataaacaagatggtaaaaatctggaaattgaacttatttcattaaag gaggctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat cattacctctgtaaagaagtagcatctccagtggtgcttgaaaatatacaaagcaattgt catggcccaatttcaatggattttgccataagtaaactgaagaaagcaggtaatcagact ggactttatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgct gtcgagcgtgataatgtcattgaatataagcactgtctgattacaaaaaatgagaatgga gaatacaacctcagtgggactaagaagaacttcagtaatcttaaagatcttttgaattgc taccagatggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtcct ccaaagccaaaagataaatcaaaccttctagtctttagaacaaatagtgtttctgatgta ccaacctcaccaacattacagagacataataatgtgaaccaaatggtgtttcacaaaatc agaaatgaagatttagtatttaatgaaagtcttggccaaggcacttttacaaaaattttt aaaggtgtaagaagagaagtaggagattatggtcaactgcatgaaacagaagttctttta aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg atgagccagctttctcacaaacatctggttttaaattatggagtatgtgtctgtggagag gagaatattctggttcaggagtttgtgaaatttggatcactagatacatatttgaaaaag aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc atgcattttctagaagaaaaaaaccttattcatgggaatgtgtgtgccaaaaacattcta cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct ggcattagtgttacagttttgccaaaggacattcttcaggagagaataccatgggtacca cctgaatgtattgaaaatcctaaaaacttaaacttggcaacagacaaatggagttttggt accactttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaa agaaagctacagttttatgaagatagacaccagcttcctgcaccaaagtggacagaatta gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc atcatacgagatcttaatagtttgtttactccagattatgaattgttaacagagaatgac atgttaccaaatatgaggataggtgccctagggttttctggagcttttgaagaccgagac cctactcagtttgaagagagacacttgaaatttctgcagcaacttggcaagggtaacttt gggagtgttgagatgtgccggtatgaccctctacaagacaacactggggaggtggtggct gtgaaaaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaa atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactat ctccaaaagcataaagaacgaatagatcataagaaacttctgcaatatacatctcaaata tgcaagggtatggaatatcttggtacaaaaaggtatatccacagggatctggcaacaagg aatatattggtagagaatgaaaacagagttaaaattggagattttgggttaaccaaagtc ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcctatattctgg tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt ggagtggttctatatgaacttttcacctatattgagaagagtaaaagtccaccagcggaa ttcatgcgtatgattggcaacgacaaacaaggacagatgattgtgtttcatttgatagaa ctcttgaagaataatggaagattaccaagaccagatggatgcccagatgagatctatgtg atcatgacagaatgctggaataataatgtaaatcagcgtccgtctttcagaaacctagct cttcgagttgatcaaataagggacaacatagctggatga

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