KEGG   Myotis brandtii (Brandt's bat): 102254628
Entry
102254628         CDS       T02920                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
myb01522  Endocrine resistance
myb04010  MAPK signaling pathway
myb04015  Rap1 signaling pathway
myb04068  FoxO signaling pathway
myb04071  Sphingolipid signaling pathway
myb04114  Oocyte meiosis
myb04148  Efferocytosis
myb04218  Cellular senescence
myb04261  Adrenergic signaling in cardiomyocytes
myb04370  VEGF signaling pathway
myb04380  Osteoclast differentiation
myb04550  Signaling pathways regulating pluripotency of stem cells
myb04611  Platelet activation
myb04613  Neutrophil extracellular trap formation
myb04620  Toll-like receptor signaling pathway
myb04621  NOD-like receptor signaling pathway
myb04622  RIG-I-like receptor signaling pathway
myb04625  C-type lectin receptor signaling pathway
myb04657  IL-17 signaling pathway
myb04658  Th1 and Th2 cell differentiation
myb04659  Th17 cell differentiation
myb04660  T cell receptor signaling pathway
myb04664  Fc epsilon RI signaling pathway
myb04668  TNF signaling pathway
myb04670  Leukocyte transendothelial migration
myb04714  Thermogenesis
myb04722  Neurotrophin signaling pathway
myb04723  Retrograde endocannabinoid signaling
myb04728  Dopaminergic synapse
myb04750  Inflammatory mediator regulation of TRP channels
myb04912  GnRH signaling pathway
myb04914  Progesterone-mediated oocyte maturation
myb04917  Prolactin signaling pathway
myb04926  Relaxin signaling pathway
myb04932  Non-alcoholic fatty liver disease
myb04933  AGE-RAGE signaling pathway in diabetic complications
myb04935  Growth hormone synthesis, secretion and action
myb04936  Alcoholic liver disease
myb05014  Amyotrophic lateral sclerosis
myb05020  Prion disease
myb05022  Pathways of neurodegeneration - multiple diseases
myb05132  Salmonella infection
myb05133  Pertussis
myb05135  Yersinia infection
myb05140  Leishmaniasis
myb05142  Chagas disease
myb05145  Toxoplasmosis
myb05152  Tuberculosis
myb05161  Hepatitis B
myb05163  Human cytomegalovirus infection
myb05167  Kaposi sarcoma-associated herpesvirus infection
myb05169  Epstein-Barr virus infection
myb05170  Human immunodeficiency virus 1 infection
myb05171  Coronavirus disease - COVID-19
myb05205  Proteoglycans in cancer
myb05208  Chemical carcinogenesis - reactive oxygen species
myb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
myb05415  Diabetic cardiomyopathy
myb05417  Lipid and atherosclerosis
myb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:myb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102254628 (MAPK12)
   04015 Rap1 signaling pathway
    102254628 (MAPK12)
   04370 VEGF signaling pathway
    102254628 (MAPK12)
   04668 TNF signaling pathway
    102254628 (MAPK12)
   04068 FoxO signaling pathway
    102254628 (MAPK12)
   04071 Sphingolipid signaling pathway
    102254628 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102254628 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102254628 (MAPK12)
   04218 Cellular senescence
    102254628 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102254628 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102254628 (MAPK12)
   04613 Neutrophil extracellular trap formation
    102254628 (MAPK12)
   04620 Toll-like receptor signaling pathway
    102254628 (MAPK12)
   04621 NOD-like receptor signaling pathway
    102254628 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    102254628 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    102254628 (MAPK12)
   04660 T cell receptor signaling pathway
    102254628 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    102254628 (MAPK12)
   04659 Th17 cell differentiation
    102254628 (MAPK12)
   04657 IL-17 signaling pathway
    102254628 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    102254628 (MAPK12)
   04670 Leukocyte transendothelial migration
    102254628 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102254628 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    102254628 (MAPK12)
   04917 Prolactin signaling pathway
    102254628 (MAPK12)
   04926 Relaxin signaling pathway
    102254628 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    102254628 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102254628 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    102254628 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    102254628 (MAPK12)
   04722 Neurotrophin signaling pathway
    102254628 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102254628 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102254628 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    102254628 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102254628 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    102254628 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102254628 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102254628 (MAPK12)
   05161 Hepatitis B
    102254628 (MAPK12)
   05171 Coronavirus disease - COVID-19
    102254628 (MAPK12)
   05163 Human cytomegalovirus infection
    102254628 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102254628 (MAPK12)
   05169 Epstein-Barr virus infection
    102254628 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102254628 (MAPK12)
   05135 Yersinia infection
    102254628 (MAPK12)
   05133 Pertussis
    102254628 (MAPK12)
   05152 Tuberculosis
    102254628 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102254628 (MAPK12)
   05140 Leishmaniasis
    102254628 (MAPK12)
   05142 Chagas disease
    102254628 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102254628 (MAPK12)
   05020 Prion disease
    102254628 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    102254628 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102254628 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    102254628 (MAPK12)
   05415 Diabetic cardiomyopathy
    102254628 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102254628 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    102254628 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102254628 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102254628 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:myb01001]
    102254628 (MAPK12)
Enzymes [BR:myb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102254628 (MAPK12)
Protein kinases [BR:myb01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102254628 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 102254628
NCBI-ProteinID: XP_014404674
LinkDB
Position
Un
AA seq 340 aa
MLALPWEAVPILVPGFQWTGRARSGSSLDGRAPIQAGAAPPPQDPSCHRPKIACICGQVI
GLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRVQFLVYQMLKGLKYIHAA
GVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMHYTQTV
DIWSVGCIMAEMITGKTLFKXXXDLDQLKEILKVTGTPPDEFVQRLQSTDAKNYMKGLPE
LEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALTHPYFESLHDAEDEPQAQKYD
ESFDDVDRTLDEWKRDTYKEVLSFRPPRQLGAKSSKETAL
NT seq 1023 nt   +upstreamnt  +downstreamnt
atgctggctctcccctgggaggcggtccccatcctcgtcccaggttttcaatggacagga
agggcccggagcgggagctccttggatggccgggcaccgatccaggctggggctgcccct
cccccacaggatcccagctgtcaccgtcccaaaatagcctgcatctgtgggcaggtgatc
gggctgctggacgtattcactccagatgagaccctggatgacttcacagacttttacctg
gtcatgccgttcatgggcacggacctgggcaagctcatgaagcacgagacgctgagcgag
gaccgcgtccagttcctcgtctaccagatgctgaaggggctgaagtatatccatgcggct
ggcgtcattcacagggacctgaagcccggcaacctggcagtgaacgaggactgtgagctg
aagatcctggacttcggcctggccaggcaggccgacagcgagatgactggatacgtagtg
acgaggtggtaccgggcgcccgaggtcatcttgaactggatgcactacacacagacagtg
gacatctggtctgtgggctgcatcatggcggagatgatcacagggaagacgctgttcaag
nnnnnnngagatctggaccagctgaaggagatcttgaaggtgacgggcacaccacccgac
gagtttgtccagaggctgcagagcacggatgcgaagaactacatgaagggcctccccgag
ttggagaagaaggattttgcctccattctgaccaatgcaagccctctggcggtgaacctc
ctggagaaaatgctggtgctggacgcagagcagcgggtgacggcggccgaggccctgacc
cacccgtacttcgagtcgctgcacgacgcggaggacgagcctcaggcccagaagtacgac
gagtccttcgatgacgtggaccgtaccctggacgagtggaagcgtgacacgtataaagag
gtgctcagcttcaggcccccccggcagctgggggccaagtcctccaaggagacggccctg
tga

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