Myotis davidii (David's myotis): 102760678 Help Entry 102760678         CDS       T02992                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism myd  Myotis davidii (David's myotis) Pathway myd00230   Purine metabolism myd01100   Metabolic pathways myd01522   Endocrine resistance myd04015   Rap1 signaling pathway myd04022   cGMP-PKG signaling pathway myd04024   cAMP signaling pathway myd04062   Chemokine signaling pathway myd04072   Phospholipase D signaling pathway myd04114   Oocyte meiosis myd04211   Longevity regulating pathway myd04213   Longevity regulating pathway - multiple species myd04261   Adrenergic signaling in cardiomyocytes myd04270   Vascular smooth muscle contraction myd04371   Apelin signaling pathway myd04540   Gap junction myd04611   Platelet activation myd04713   Circadian entrainment myd04714   Thermogenesis myd04723   Retrograde endocannabinoid signaling myd04724   Glutamatergic synapse myd04725   Cholinergic synapse myd04726   Serotonergic synapse myd04727   GABAergic synapse myd04728   Dopaminergic synapse myd04750   Inflammatory mediator regulation of TRP channels myd04911   Insulin secretion myd04912   GnRH signaling pathway myd04913   Ovarian steroidogenesis myd04914   Progesterone-mediated oocyte maturation myd04915   Estrogen signaling pathway myd04916   Melanogenesis myd04918   Thyroid hormone synthesis myd04921   Oxytocin signaling pathway myd04923   Regulation of lipolysis in adipocytes myd04924   Renin secretion myd04925   Aldosterone synthesis and secretion myd04926   Relaxin signaling pathway myd04927   Cortisol synthesis and secretion myd04928   Parathyroid hormone synthesis, secretion and action myd04934   Cushing syndrome myd04935   Growth hormone synthesis, secretion and action myd04970   Salivary secretion myd04971   Gastric acid secretion myd04972   Pancreatic secretion myd04976   Bile secretion myd05012   Parkinson disease myd05030   Cocaine addiction myd05031   Amphetamine addiction myd05032   Morphine addiction myd05034   Alcoholism myd05163   Human cytomegalovirus infection myd05166   Human T-cell leukemia virus 1 infection myd05200   Pathways in cancer myd05207   Chemical carcinogenesis - receptor activation myd05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:myd00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102760678 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102760678 (ADCY5)    04371 Apelin signaling pathway     102760678 (ADCY5)    04072 Phospholipase D signaling pathway     102760678 (ADCY5)    04024 cAMP signaling pathway     102760678 (ADCY5)    04022 cGMP-PKG signaling pathway     102760678 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102760678 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102760678 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102760678 (ADCY5)    04062 Chemokine signaling pathway     102760678 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102760678 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102760678 (ADCY5)    04912 GnRH signaling pathway     102760678 (ADCY5)    04913 Ovarian steroidogenesis     102760678 (ADCY5)    04915 Estrogen signaling pathway     102760678 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102760678 (ADCY5)    04921 Oxytocin signaling pathway     102760678 (ADCY5)    04926 Relaxin signaling pathway     102760678 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102760678 (ADCY5)    04918 Thyroid hormone synthesis     102760678 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102760678 (ADCY5)    04916 Melanogenesis     102760678 (ADCY5)    04924 Renin secretion     102760678 (ADCY5)    04925 Aldosterone synthesis and secretion     102760678 (ADCY5)    04927 Cortisol synthesis and secretion     102760678 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102760678 (ADCY5)    04270 Vascular smooth muscle contraction     102760678 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102760678 (ADCY5)    04971 Gastric acid secretion     102760678 (ADCY5)    04972 Pancreatic secretion     102760678 (ADCY5)    04976 Bile secretion     102760678 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102760678 (ADCY5)    04727 GABAergic synapse     102760678 (ADCY5)    04725 Cholinergic synapse     102760678 (ADCY5)    04728 Dopaminergic synapse     102760678 (ADCY5)    04726 Serotonergic synapse     102760678 (ADCY5)    04723 Retrograde endocannabinoid signaling     102760678 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102760678 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102760678 (ADCY5)    04213 Longevity regulating pathway - multiple species     102760678 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102760678 (ADCY5)    04714 Thermogenesis     102760678 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102760678 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102760678 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102760678 (ADCY5)    05163 Human cytomegalovirus infection     102760678 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102760678 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102760678 (ADCY5)    05031 Amphetamine addiction     102760678 (ADCY5)    05032 Morphine addiction     102760678 (ADCY5)    05034 Alcoholism     102760678 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102760678 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102760678 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102760678 (ADCY5) Enzymes [BR:myd01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102760678 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC HILPDA Motif Other DBs NCBI-GeneID:  102760678 NCBI-ProteinID:  XP_006772960 LinkDB All DBs Position Un AA seq 994 aa AA seqDB search LSVLTAAVGAILVMAVLCNRAAFHQDHMGLACYALIAVVLVVQVVGLLLPQPRSASEGIW WTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALHTNAQDQFLLKQLVSNVLIFSCTN IVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINA KQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRV HCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNA YLKEHSIELFLIVSCSRSLIFKKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGSN QVSKEMKRMGFEDPKDKFAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREP DLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSVFMLSFYLTCFVLLTLVVFVS VIYSCVKLFPGPLQTLSRKIVRSKMNSTLVGVFTITLVFLSAFVNMFMCNSQDLFGCLAD EHNVSTSQVNACHVVESAFNYSLGDEQGFCSSPWPNCNFPEYFTYSVLLSLLACSVFLQI SCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLVTANAIDFNNNGTSQCPEHATKVALK VVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKD VAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADF DEIISEDRFKQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINE HSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQV LAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 2985 nt NT seq  +upstreamnt  +downstreamnt ctgtccgtgctgacggccgccgtgggcgccatcctcgtgatggccgtgctctgcaaccgc gccgccttccaccaggaccacatgggcctggcctgctatgcgctgattgcggtggtgctg gtggtccaggtggtgggcctgctgctgccccagccgcgcagcgcctccgagggcatctgg tggaccgtgttcttcatctacaccatctacacgctgctgcccgtgcgcatgcgggccgcg gtgctcagcggggtactcctgtctgccctccacttggcgattgccctgcacaccaacgcc caggaccagttcctgctcaagcagctcgtctccaatgtcctcattttctcctgcaccaac atcgtgggcgtctgcacccactacccggccgaggtctcccagagacaagccttccaggag acccgggagtgcatccaggcgcgactccactctcagcgggagaaccagcagcaggagcgg ctcctgctatctgtccttccccggcatgttgccatggagatgaaagcagacatcaacgcc aagcaggaggatatgatgttccataagatttacatccagaagcatgacaacgtgagcatc ctgttcgctgacatcgagggcttcaccagcctggcgtcccagtgcactgcccaggagctg gtcatgaccctcaacgagctctttgcccgcttcgacaagctggctgcggagaatcactgt ttacgtataaagatcctgggggattgttattactgcgtctcggggctgcctgaagcgagg gctgaccacgcccactgctgcgtggagatgggcatggacatgatcgaggccatctcgttg gtccgggaggtgacaggggtgaacgtgaacatgcgcgtgggaattcacagcgggcgagta cactgcggtgtccttggtctcaggaagtggcagttcgacgtctggtctaacgacgtcacg ctggccaaccacatggaggctggaggcaaggctggacgcatccacatcaccaaggccaca ctcaactacctgaacggggactacgaggtggagccaggctgtgggggcgagcgcaacgcc tacctcaaggagcacagcatcgagctatttttaatagtgtcatgttccaggtccttaatt tttaaaaaagaagagaaggccatgattgccaagatgaatcgccagagaaccaactccatc gggcacaacccgccacactggggagccgagcgccccttctacaaccacctgggcagcaac caggtgtccaaggagatgaagcggatgggctttgaagaccccaaggacaagtttgcccag gaaagtgcaaaccccgaagatgaagtggacgagtttctgggccgtgccattgacgccagg agcattgacaggctgcggtctgagcatgttcgcaagttcctcttgaccttcagggagcct gacttagagaagaagtactccaagcaggtggacgaccgattcggtgcctacgtggcgtgc gcctcgctcgtcttcctcttcatctgctttgtccagatcaccatcgtgccccactctgtg ttcatgctgagcttctacctgacctgtttcgtgctgctgaccttggtggtatttgtgtcc gtgatctactcctgcgtgaagctcttcccaggccccctgcagaccctctccaggaagatc gtgcggtctaagatgaacagcaccctggtcggggtgttcaccatcaccctggtgttcctg tcggcttttgtcaacatgttcatgtgcaactcccaggacctgttcggctgcctggcagat gaacacaacgtcagcaccagccaggtcaacgcgtgccatgtggtggagtccgccttcaac tacagcctgggggacgagcagggcttctgcagcagcccctggcccaactgcaacttcccc gagtacttcacctacagcgtgctgctgagcctgctggcctgctccgtgttcctgcaaatc agctgcatcgggaagctggtgctgatgctggccatcgagctcatatacgtgctcgtcgtc gaggtgcccggcgtaacgctctttgacaatgccgaccttctggtcaccgccaatgctata gacttcaacaacaacgggacctcccagtgccctgagcacgcgaccaaggtggcgctgaag gtggtgacgcccatcatcatctcagtcttcgtgctggccctgtacctgcacgcccagcag gtggagtccaccgcccgcctcgacttcctctggaaactgcaggccacggaggagaaggag gagatggaggagctgcaggcctacaaccggcggctgctgcacaacattctgcccaaggac gtggccgcccacttcctggcccgggagcggcgcaacgatgagctctactaccagtcgtgc gagtgcgtggccgtcatgttcgcctccatcgccaacttctccgagttctacgtggagctg gaggccaacaacgagggtgtcgagtgcctgcggctgctcaacgagatcattgccgacttc gatgagatcatcagcgaggatcggtttaagcagctggaaaagatcaagaccatcggcagc acctacatggctgcctccggccttaatgattccacctacgacaaggtgggcaagacgcac atcaaagctctggccgacttcgccatgaagctgatggaccaaatgaagtacatcaacgag cactccttcaacaacttccagatgaagattgggctcaatattggccccgtggtggctggg gtgatcggggcccgcaagcctcagtacgacatctggggcaatacggtgaacgtggccagc cgcatggacagcaccggtgtgccagaccgcatccaggtcaccacggacatgtaccaggtg ctggctgccaacacgtaccagctggagtgccggggtgtggtcaaggtcaagggcaaaggc gagatgatgacctacttcctcaacggagggcccccgctcagttag

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