Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112394646
Help
Entry
112394646 CDS
T08872
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi01522
Endocrine resistance
nasi04010
MAPK signaling pathway
nasi04015
Rap1 signaling pathway
nasi04068
FoxO signaling pathway
nasi04071
Sphingolipid signaling pathway
nasi04114
Oocyte meiosis
nasi04148
Efferocytosis
nasi04218
Cellular senescence
nasi04261
Adrenergic signaling in cardiomyocytes
nasi04370
VEGF signaling pathway
nasi04380
Osteoclast differentiation
nasi04550
Signaling pathways regulating pluripotency of stem cells
nasi04611
Platelet activation
nasi04613
Neutrophil extracellular trap formation
nasi04620
Toll-like receptor signaling pathway
nasi04621
NOD-like receptor signaling pathway
nasi04622
RIG-I-like receptor signaling pathway
nasi04625
C-type lectin receptor signaling pathway
nasi04657
IL-17 signaling pathway
nasi04658
Th1 and Th2 cell differentiation
nasi04659
Th17 cell differentiation
nasi04660
T cell receptor signaling pathway
nasi04664
Fc epsilon RI signaling pathway
nasi04668
TNF signaling pathway
nasi04670
Leukocyte transendothelial migration
nasi04714
Thermogenesis
nasi04722
Neurotrophin signaling pathway
nasi04723
Retrograde endocannabinoid signaling
nasi04728
Dopaminergic synapse
nasi04750
Inflammatory mediator regulation of TRP channels
nasi04912
GnRH signaling pathway
nasi04914
Progesterone-mediated oocyte maturation
nasi04917
Prolactin signaling pathway
nasi04926
Relaxin signaling pathway
nasi04932
Non-alcoholic fatty liver disease
nasi04933
AGE-RAGE signaling pathway in diabetic complications
nasi04935
Growth hormone synthesis, secretion and action
nasi04936
Alcoholic liver disease
nasi05014
Amyotrophic lateral sclerosis
nasi05020
Prion disease
nasi05022
Pathways of neurodegeneration - multiple diseases
nasi05132
Salmonella infection
nasi05133
Pertussis
nasi05135
Yersinia infection
nasi05140
Leishmaniasis
nasi05142
Chagas disease
nasi05145
Toxoplasmosis
nasi05152
Tuberculosis
nasi05161
Hepatitis B
nasi05163
Human cytomegalovirus infection
nasi05167
Kaposi sarcoma-associated herpesvirus infection
nasi05169
Epstein-Barr virus infection
nasi05170
Human immunodeficiency virus 1 infection
nasi05171
Coronavirus disease - COVID-19
nasi05205
Proteoglycans in cancer
nasi05208
Chemical carcinogenesis - reactive oxygen species
nasi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
nasi05415
Diabetic cardiomyopathy
nasi05417
Lipid and atherosclerosis
nasi05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112394646 (MAPK12)
04015 Rap1 signaling pathway
112394646 (MAPK12)
04370 VEGF signaling pathway
112394646 (MAPK12)
04668 TNF signaling pathway
112394646 (MAPK12)
04068 FoxO signaling pathway
112394646 (MAPK12)
04071 Sphingolipid signaling pathway
112394646 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
112394646 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
112394646 (MAPK12)
04218 Cellular senescence
112394646 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112394646 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112394646 (MAPK12)
04613 Neutrophil extracellular trap formation
112394646 (MAPK12)
04620 Toll-like receptor signaling pathway
112394646 (MAPK12)
04621 NOD-like receptor signaling pathway
112394646 (MAPK12)
04622 RIG-I-like receptor signaling pathway
112394646 (MAPK12)
04625 C-type lectin receptor signaling pathway
112394646 (MAPK12)
04660 T cell receptor signaling pathway
112394646 (MAPK12)
04658 Th1 and Th2 cell differentiation
112394646 (MAPK12)
04659 Th17 cell differentiation
112394646 (MAPK12)
04657 IL-17 signaling pathway
112394646 (MAPK12)
04664 Fc epsilon RI signaling pathway
112394646 (MAPK12)
04670 Leukocyte transendothelial migration
112394646 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
112394646 (MAPK12)
04914 Progesterone-mediated oocyte maturation
112394646 (MAPK12)
04917 Prolactin signaling pathway
112394646 (MAPK12)
04926 Relaxin signaling pathway
112394646 (MAPK12)
04935 Growth hormone synthesis, secretion and action
112394646 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
112394646 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
112394646 (MAPK12)
04723 Retrograde endocannabinoid signaling
112394646 (MAPK12)
04722 Neurotrophin signaling pathway
112394646 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112394646 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
112394646 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
112394646 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
112394646 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
112394646 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112394646 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112394646 (MAPK12)
05161 Hepatitis B
112394646 (MAPK12)
05171 Coronavirus disease - COVID-19
112394646 (MAPK12)
05163 Human cytomegalovirus infection
112394646 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
112394646 (MAPK12)
05169 Epstein-Barr virus infection
112394646 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
112394646 (MAPK12)
05135 Yersinia infection
112394646 (MAPK12)
05133 Pertussis
112394646 (MAPK12)
05152 Tuberculosis
112394646 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112394646 (MAPK12)
05140 Leishmaniasis
112394646 (MAPK12)
05142 Chagas disease
112394646 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
112394646 (MAPK12)
05020 Prion disease
112394646 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
112394646 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112394646 (MAPK12)
05418 Fluid shear stress and atherosclerosis
112394646 (MAPK12)
05415 Diabetic cardiomyopathy
112394646 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
112394646 (MAPK12)
04932 Non-alcoholic fatty liver disease
112394646 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
112394646 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
112394646 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nasi01001
]
112394646 (MAPK12)
Enzymes [BR:
nasi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
112394646 (MAPK12)
Protein kinases [BR:
nasi01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
112394646 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Kdo
Kinase-like
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
112394646
NCBI-ProteinID:
XP_024593241
UniProt:
A0A341ARK2
LinkDB
All DBs
Position
Unknown
AA seq
424 aa
AA seq
DB search
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPNETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGETLFKGSDRILYLELGAG
EACLTPGAGCGGGLPYTCGGQARRTARAGWVGELCPLAPRCAPDLSQDLDQLKEIMKVTG
TPPAEFVQRLQSAEAQNYMNGLPELEKKDFAAILTNASPLAVNLLEKMLVLDAERRVTAA
KALTHPYFESLHDTEDEPKAQKYDESFDDVDRTLEEWKRVTYREVLSFKPPRQLGAKVSK
ETAL
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgccgcccgcccgcaagggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtaggctcgggcgcctatggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggtggccataaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccatgagaacgtaattgggctgctggatgtgttcacacccaatgagaccctggat
gatttcacagacttttacctggtgatgccgttcatgggcaccgacctggggaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttcctcgtctaccagatgctcaagggg
ctgaagtacatccatgctgctggcatcatccacagggacctgaagcccggcaacctggcc
gtgaacgaggactgtgagctcaagatcctggactttggcctggcccggcaggcagatagc
gagatgactgggtacgtggtgacccggtggtaccgggcgcctgaggtcatcttgaattgg
atgcactacacacagacggtggacatctggtcagtgggctgcatcatggctgagatgatc
acaggggagacgctcttcaaaggcagcgaccgtatcctatacctggagctgggtgcgggg
gaggcttgccttacacctggagctgggtgcgggggaggcttgccctacacctgcgggggg
caggccaggcgcactgcccgggctgggtgggtaggtgagctctgccctctggccccgcgc
tgtgctcctgacctcagccaagacctggaccagctgaaggagatcatgaaggtgacgggg
acgcctcccgccgagttcgtgcagaggctgcagagtgccgaggctcagaactacatgaac
ggcctccccgagctagagaaaaaggattttgccgccatcctgaccaacgcaagccctctg
gccgtgaacctcctggagaagatgctcgtgctggatgcggagcggcgggtgacggcggcc
aaggcgctgacccacccctacttcgagtcgctgcacgacacggaggacgagcccaaagcc
caaaagtacgatgaatcctttgatgacgtggaccgcacgctggaagagtggaagcgcgtc
acatacagagaggtgctcagcttcaagcctccccgacagctgggggccaaggtctccaag
gagacggccctgtga
DBGET
integrated database retrieval system