KEGG   Sciurus carolinensis (gray squirrel): 124958984
Entry
124958984         CDS       T08117                                 
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar00350  Tyrosine metabolism
ncar00790  Folate biosynthesis
ncar01100  Metabolic pathways
ncar04728  Dopaminergic synapse
ncar04917  Prolactin signaling pathway
ncar05012  Parkinson disease
ncar05030  Cocaine addiction
ncar05031  Amphetamine addiction
ncar05034  Alcoholism
Module
ncar_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    124958984
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    124958984
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    124958984
  09156 Nervous system
   04728 Dopaminergic synapse
    124958984
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    124958984
  09165 Substance dependence
   05030 Cocaine addiction
    124958984
   05031 Amphetamine addiction
    124958984
   05034 Alcoholism
    124958984
Enzymes [BR:ncar01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     124958984
SSDB
Motif
Pfam: Biopterin_H TH_ACT TOH_N LTP_2
Other DBs
NCBI-GeneID: 124958984
NCBI-ProteinID: XP_047373565
EnsemblRapid: ENSSCRG00010014046
LinkDB
Position
11:complement(5128172..5137118)
AA seq 496 aa
MPTPNATTPQPKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAAAAAAASS
LEPGDPLEAVAFQEKDGRALLSLLFSLKGSKSCSLSRAVKVFETFEAKIHHLETRPAQRP
RAGGPHLDYFVRFEVPSGDLAALLSSVRRVSDDVRSAGEDKVPWFPRKVSELDKCHHLVT
KFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKHGEPIPRVEYTAEEIATWKEVYSTLKG
LYATHACREHLEAFQLLELCSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLA
SLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDE
EIEKLSTLYWFTVEFGLCRQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPEAAAVQP
YQDQTYQPVYFVSESFSDAKDKLRGYASRIQRPFSVKFDPYTTAIDVLDSPHTIRRSLEG
VQDELHTLTHALSAIS
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgcccacacccaacgccaccacaccacagcccaagggcttccgaagggccgtctcagag
ctggacgccaagcaggcagaggccatcatgtccccgcgcttcatcgggcggcggcagagc
ctcatcgaggacgcccgcaaggagcgggaggcggcggcggcagcggcagcggcaagctcc
ttggagcccggggaccccctggaggccgtggcgttccaggagaaggacgggagggccctg
ctgagcctgctcttctccctgaagggctccaagtcctgctcgctgtcccgggccgtgaag
gtgtttgagacatttgaagccaaaatccaccacctggagacccggccagcccagaggcca
cgggcagggggccctcacctggactactttgtgcgctttgaggtgcccagcggggatctg
gctgccctgctcagctccgtgcgccgggtgtcagacgacgtgcgcagtgctggggaggac
aaggtcccatggttcccaaggaaggtgtcagagctggacaagtgtcaccacctggtcacc
aagtttgatcctgacttggacttggaccacccgggcttctcggaccaggcctaccgccag
cgcaggaagctgatcgctgagatagccttccagtacaagcatggtgaacccattccccgt
gtggagtacacagccgaggagattgccacctggaaggaggtctacagcacgctgaagggc
ctgtacgccacccatgcctgccgggagcacctggaagccttccagctgctggagctctgc
agcggctaccgcgaggacagcatccctcagctcgaggacgtctcgcgcttcctgaaggag
cggacaggcttccagcttcgacctgtggctggccttctgtctgccagggacttcctggcc
agcctggccttccgcgtgttccagtgcacccagtacatccgccacgcctcttcgcccatg
cactcgccggagccggactgctgccatgagctgctggggcacgtgcccatgctggctgac
cgcacgttcgcacagttctcccaggacatcggccttgcgtccctgggggcctcggatgag
gaaatcgagaagctgtccacgctgtattggttcacggtggagttcgggctgtgcagacag
aacggggaggtcaaggcttacggcgccgggctgctgtcgtcctacggggagctcctgcac
tccctgtcagaggagcccgagatccgggccttcgaccccgaggctgccgccgtgcagccc
taccaagatcagacctaccagcccgtctacttcgtgtctgagagcttcagtgacgccaag
gacaagctcaggggctatgcctctcgaatccagcgccctttctctgtgaagtttgaccca
tacacgacggccattgatgtgctggacagtccccacaccatccgtcgctcgctggagggc
gtccaggatgagctgcacaccctgacccacgcactgagcgccatcagctag

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