Sciurus carolinensis (gray squirrel): 124979930
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Entry
124979930 CDS
T08117
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar04140
Autophagy - animal
ncar04141
Protein processing in endoplasmic reticulum
ncar04210
Apoptosis
ncar04932
Non-alcoholic fatty liver disease
ncar05010
Alzheimer disease
ncar05012
Parkinson disease
ncar05014
Amyotrophic lateral sclerosis
ncar05016
Huntington disease
ncar05017
Spinocerebellar ataxia
ncar05022
Pathways of neurodegeneration - multiple diseases
ncar05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
124979930
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
124979930
09143 Cell growth and death
04210 Apoptosis
124979930
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
124979930
05012 Parkinson disease
124979930
05014 Amyotrophic lateral sclerosis
124979930
05016 Huntington disease
124979930
05017 Spinocerebellar ataxia
124979930
05022 Pathways of neurodegeneration - multiple diseases
124979930
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
124979930
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
124979930
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ncar01001
]
124979930
Enzymes [BR:
ncar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
124979930
Protein kinases [BR:
ncar01001
]
Serine/threonine kinases: Other
IRE family
124979930
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
124979930
NCBI-ProteinID:
XP_047400812
EnsemblRapid:
ENSSCRG00010010366
LinkDB
All DBs
Position
3:14500279..14578606
Genome browser
AA seq
976 aa
AA seq
DB search
MPAWRLLLLLLALLLPGPRIFGNTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEDVINLVDQTSENAPTTMS
QDVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQQLPFHPPGELTQDAELLDTSGPYSESSGTSSPSPSPRASNHSLHSGS
SASKAGASPFLEQDEEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRI
LPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFSHL
GLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVG
RHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQR
QANILLGAYSLECFHPEKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQF
FQDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLL
RAMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCSHERLFQPYY
FHEPLEPQPPLTPDAL
NT seq
2931 nt
NT seq
+upstream
nt +downstream
nt
atgccggcctggcggctgttgctgctgctgctggcgctgctattgcccggccccaggatt
tttggaaacaccagcacagtgacactgcctgaaaccttgttgttcgtgtcaacgctggat
gggagtttgcatgctgtcagcaagaggacaggctccatcaaatggactttaaaagaagac
ccagtgctgcaggttccgacacatgttgaagagcctgccttcctcccagatcccaatgat
ggcagcctatatacacttgggggcaagaataatgaaggcctaacgaaacttccctttacc
atcccagagttggtacaggcatccccatgccgaagttcagatggaatcctctacatgggt
aaaaagcaggacatttggtatgtcattgacctcttgactggtgagaagcagcagactttg
tcatcagcctttgctgatagtctctgcccatcaacctctcttctgtatcttggacggaca
gaatacaccatcaccatgtatgacaccaaaacccgcgagctccgctggaacgccacctac
tttgactatgcagcctcgctgcccgaggacgacatggactacaagatgtcccactttgtg
tccaatggtgatggactggtggtgactgtggatagtgaatctggggacgtcctgtggatt
caaaactatgcctccccagtggtggccttctacgtctggcagcgggagggtctgaggaag
gtgatgcacatcaatgttgctgtggagaccctgcgctacctgaccttcatgtctggggag
gtgggtcgcatcaccaagtggaagtacccgttccccaaagagacggaggccaagagcaaa
ctgacgcccaccctgtatgttgggaagtactccaccagcctctatgcctctccctcgatg
gtgcacgagggggttgccgttgtgccccgtggcagcacccttcctttgctggaaggcccc
cagactgatggtgtcaccattggggacaaaggggaatgtgtgatcacacccagcacggac
ctcaagtttgaccctggactgaaagggaagaacaagctcaactacttgaggaattactgg
ctcctaataggacaccatgaaaccccactgtctgcatctaccaagatgctggagagattt
cccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcggagaaaaagagc
tttgaggacgtaatcaacctggttgatcagacttcagaaaatgcaccaaccaccatgtct
caggatgtggaagagaagttggctcgtgcccctgccaagcccgaggcccctgtggactcc
atgctcaaggacatggccaccatcatcctgagcaccttcctgctggttggctgggtagcc
ttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcagttc
caaaaggaactggagaaaatccagctcctgcagcagcagcagctgcccttccacccacct
ggagaattgacccaggacgccgagctcctggacacatcaggcccctactcggaaagctca
ggcaccagcagccccagcccatctcccagagcttccaaccactcgctgcactctggcagt
tctgcctccaaggctggtgccagccccttcctggagcaggatgaggaagatgaggaaacc
agcatggtgatggttgggaaaatttcattctgtcccaaggatgtcctgggccatggagct
gagggcaccattgtgtaccggggcatgtttgacaaccgtgatgtggctgtgaagaggatt
ctccctgagtgtttcagctttgcagaccgtgaggtccagctgttacgagaatcagatgag
cacccaaatgtgatccgttacttctgcacagagagggaccggcagttccaatatattgcc
attgagctgtgtgcagccaccctgcaggagtatgtggagcagaaggacttctcccacctt
ggcctagagcccatcaccttgctgcagcagaccacctcaggcctggcacacctccactcg
ctcaacattgttcacagagatctgaagcctcacaacattctcctctccatgcccaatgca
cacggcaggatcaaggccatgatctctgactttggcctctgtaagaagctggcggtgggc
cggcacagcttcagtcgccgttccggggtgcctggcaccgaaggctggatcgccccagag
atgctgagcgaagactgcaaggagaaccccacctacacagtggacatcttctctgcaggc
tgcgtcttctactacgtcatctctgagggcagccacccctttggcaagtccctgcagcgg
caggccaacatcctcctcggcgcctacagccttgagtgcttccacccagagaagcacgaa
gatgtcattgcccgcgagttgatagagaaaatgattgccatggatccccagcagcggccc
tcagcgaagcacgtgctgaaacaccctttcttctggagtctggaaaagcagctgcagttc
tttcaggacgtgagcgaccgaatagaaaaggagtccctggatggcccgatagtgaggcag
ttagaaagaggcgggagagcggtggtgaagatggactggcgggagaacatcaccgtcccc
ctccagacagatctacgtaaattcagaacttacaaaggtggctccgtcagagatctcctt
cgagccatgagaaataagaagcaccactaccgggagctcccagtggaggtgcgggagacg
ctgggctccctcccggacgactttgtgcgctacttcacctcgcgcttcccccacctcctc
tcgcacacctaccgggccatggagctgtgcagccacgagagactcttccagccctactac
ttccatgagcccctggagcctcagcccccactgactccagatgccctctga
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