Sciurus carolinensis (gray squirrel): 124988811
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Entry
124988811 CDS
T08117
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar00270
Cysteine and methionine metabolism
ncar00480
Glutathione metabolism
ncar01100
Metabolic pathways
ncar01240
Biosynthesis of cofactors
ncar04216
Ferroptosis
Module
ncar_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
124988811
09106 Metabolism of other amino acids
00480 Glutathione metabolism
124988811
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
124988811
Enzymes [BR:
ncar01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
124988811
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
124988811
NCBI-ProteinID:
XP_047414542
EnsemblRapid:
ENSSCRG00010008639
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Position
7:102521017..102568366
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRYADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSVLEENQALCTITSFPRLGCPGFTLPEYKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKKNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYQQLLQ
EGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGNAVVDGRGKAQSSSELAAEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSIITDEMNYS
LIVKCNQIANELCECPELLGPAFRKVKYSGSKTDASN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctactgtcccagggctcgcctctgagctgggaggagacccagcgctacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcatttgatcat
gaaaataaaaaggtccagttggtcctgtctggagaagatgttcttgaaactttacaagag
aaaggggaaaggacaaacccaaaccatcctaccctttggagaccagagtatgggagttac
atgattgaaggaacacctgggcagccctatggaggaacaatgtctgagttcaacacagtt
gaggataacatgagaaaacgccggaaggaggctacttctgtactagaagaaaatcaggct
ctttgcactataacttcatttcccagattaggctgccctgggttcacactgcctgagtac
aaacccaacccagttgaaggaggagcttccaagtccctcttctttcctgatgaagcgata
aacaagcacccccgcttcagtaccctaacgagaaatattcggcataggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaacacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttccaagccagatcatatttacatggatgcc
atgggatttgggatgggaaattgctgtcttcaggtgacattccaagcctgcagcatatct
gaagccagatacctttatgatcagttggccactatctgtccaattgttatggctttgagt
gctgcatctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggaaagaggactggagccactgaagaagaat
aattataggattagtaaatcccggtatgattcaatagacagctacttatctaagtgtggt
gagaaatacaatgacatcgacttgaccatagataaagaaatctaccagcagctgctgcag
gaaggccttgatcatctcctggcccaacacgttgcccatctctttattagagacccactg
actctgtttgaagagaaaatacatctggatgatgccaatgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagacatt
ggatggagagtagagttccgacccatggaggtgcaattaacagactttgagaactctgcc
tatgtggtgtttgtggtcctgctcaccagggtgatcctatcgtacaaattggattttctc
attccactgtcaaaggttgatgaaaacatgaaagtagcacagaaacgagatgctgttctg
cagggaatgttttatttcaggaaagatatttgcaaaggtggtaatgctgtggtggacggt
cgtggcaaagcccagagcagctcggagctggctgcggaggagtacaccctcatgagcata
gacaccatcatcaatgggaaggaaggtgtgtttcctggactcatcccaattctgaattct
tatcttgaaaacatggaagtggatgtggacaccagatgtagtattctgaactacttaaag
ctaattaagaagagagcttctggtgaactgatgacggtagccagatggatgagagagttt
atcgcaaaccatccggactacaagcaagacagtataataactgatgaaatgaactatagc
cttattgtgaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttactagga
ccagcatttaggaaagtaaaatacagtggaagtaaaactgacgcttccaactaa
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