Neisseria dentiae: H3L92_04855
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Entry
H3L92_04855 CDS
T07671
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ndn
Neisseria dentiae
Pathway
ndn00790
Folate biosynthesis
ndn01100
Metabolic pathways
ndn01240
Biosynthesis of cofactors
Module
ndn_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ndn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
H3L92_04855 (folC)
Enzymes [BR:
ndn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
H3L92_04855 (folC)
6.3.2.17 tetrahydrofolate synthase
H3L92_04855 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Met_asp_mut_E
LSDAT_euk
Motif
Other DBs
NCBI-ProteinID:
QMT46110
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Position
1026457..1027743
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AA seq
428 aa
AA seq
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MKTLNDWLSHLETAHSAGLIDMGLARVGKVKNTMRLEPQCPVVVVAGTNGKGSVCAFLTQ
IYKQAGFKVGTLTSPHLLKYNERICINGGPVSDETITASFERIEAARGGVSLTYFEFNTL
AAVDIFMRENVDVMVLEVGLGGRLDAVNVFDADCAVVTSVDLDHQSFLGDTVEAVGYEKA
GVFRSGKPAVCGQNPPPESLRRHAESIGANLLLAKRDFDFSRMEQQQWSFHFHPTAASGL
SDGLKRNRNALPVPALRGAYQLGNAACALAVIECLNPRLPIDIGSIKRGLLLVHNPGRFQ
VLPGRPLTILDVAHNPHAARALRQGLIALPFAEKRTAVFSILADKDSDGVIDIVKDQFDQ
WYIAPLHLPRGMSGEEIAQKLNRCGIDAVQSFENIQAAYQAALAQAGENDRITVFGSFHT
VAEVMAIL
NT seq
1287 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacattaaacgactggttatcgcatctcgaaaccgcccacagcgcagggctgatt
gacatgggtctggcgcgcgtgggcaaagtgaaaaacaccatgcggctcgaaccgcaatgc
cccgtggtggtggtggcgggcaccaacggcaaaggctcggtgtgcgcattcctcacccag
atttacaagcaggccggttttaaagtcggcacgctcaccagcccgcacctgctcaaatac
aacgaacgcatctgcatcaacggcgggcctgtaagcgacgaaacgattacggcctcgttc
gagcgcatcgaagcagcgcgcggcggtgtttccctcacttatttcgagttcaacacgctg
gccgccgtcgatatttttatgcgcgaaaacgttgatgtgatggtgctcgaagtcggcctc
ggcgggcgtttggatgcggtaaacgttttcgatgccgactgcgccgtcgtaaccagcgtc
gatctcgaccaccaatcgtttctgggcgacaccgtcgaagctgtcggctacgaaaaagcc
ggcgtgttccgcagcggcaaacccgccgtttgcggccaaaacccgccgcccgaatcgctg
cgccggcacgccgaaagcataggagccaacctgctcttggccaaacgcgatttcgatttc
agccgcatggaacagcagcaatggtcgttccacttccatcccaccgccgcatcggggctt
tcagacggcctcaaacgcaaccgcaacgccctgcccgtgcccgccctgcgcggcgcctac
caactgggcaacgccgcctgcgcgctggccgttatcgaatgcctcaacccgcgcctgccc
atcgacatcggctccatcaagcgcgggctgctgctggttcacaaccccggccgcttccaa
gtgctgcccggccggccgctcaccatactcgacgtcgcccacaacccgcacgccgcgcgt
gccctgcgccaggggctgattgccctacctttcgccgaaaagcgcaccgccgtgttcagc
attctggccgacaaagattcagacggcgttatcgacatcgtgaaagaccagttcgaccaa
tggtatatcgccccgctgcatctgccgcgcggcatgagtggcgaagaaatagcgcaaaaa
ctcaaccgctgcggcatcgatgccgtgcaaagctttgaaaatattcaagcggcctatcaa
gccgctttggcgcaggccggggaaaatgatagaattaccgttttcggttctttccacacc
gttgccgaagtcatggccattttgtaa
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