Nonomuraea fuscirosea: OIE67_51485
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Entry
OIE67_51485 CDS
T09742
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
nfs
Nonomuraea fuscirosea
Pathway
nfs00280
Valine, leucine and isoleucine degradation
nfs00640
Propanoate metabolism
nfs00785
Lipoic acid metabolism
nfs01100
Metabolic pathways
nfs01110
Biosynthesis of secondary metabolites
nfs01210
2-Oxocarboxylic acid metabolism
Module
nfs_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nfs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
OIE67_51485 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
OIE67_51485 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OIE67_51485 (pdhA)
Enzymes [BR:
nfs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
OIE67_51485 (pdhA)
BRITE hierarchy
Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
WSA52358
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Position
11135361..11136452
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AA seq
363 aa
AA seq
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MTTDASRGAEAPPELVQLLTPEGERVEHPDYDIDLSPEEVRSLYRDLTLVRRIDLEAVAL
QRQGELGIWASLLGQEAAQIGSGRALTDSDMAFPTYREHGVAWCRDVDPVKLLGLFRGVN
HGGWDPEEHNFHLYTIVIGSQTLHAVGYAMGIQRDDANAATIVYFGDGATSQGDVNESFI
WASVFNAPIVFFCQNNQWAISEPLEKQTRIPLYRRASGFGFPGIRVDGNDVFACLAVTRK
ALEAARTGQGPTLIEAFTYRMGAHTTTDDPTRYRVASELEAWKLKDPIERVKSYLFKNEL
ADQAFFDSVDAEADQLGADLRRRCLAMPDPEPLDIFDHVYREPHSLIDRERAQFAGYLEG
FRD
NT seq
1092 nt
NT seq
+upstream
nt +downstream
nt
atgacaaccgacgcctctcgtggtgccgaagcacctccggagctcgtccagctgctcacc
cccgagggcgagcgggtcgagcaccccgactacgacatcgacctgagcccggaggaggtc
cggtcgctctaccgcgacctgacgctcgtccggcgcatcgacctggaggccgtggcgctg
cagcgccagggcgagctgggcatctgggcctcgctgctcggccaggaggccgcccagatc
ggctcgggccgcgctctgaccgactccgacatggccttccccacctaccgcgagcacggc
gtcgcctggtgccgcgacgtggacccggtgaagctgctggggctgttcaggggggtcaac
cacggcgggtgggaccccgaggagcacaacttccacctgtacacgatcgtgatcggcagc
cagaccctgcacgcggtcggctacgccatgggcatccagcgcgacgacgccaacgccgcc
acgatcgtctacttcggtgacggcgccacctcgcagggcgacgtcaacgagtcgttcatc
tgggccagcgtgttcaacgcgccgatcgtgttcttctgccagaacaaccagtgggccatc
tccgagccgctggagaagcagacccgcatcccgctctaccgccgggcctcgggcttcggc
ttccccggcatcagggtcgacggcaacgacgtgttcgcctgcctggccgtgacgcgcaag
gcgctcgaagccgcccgtacggggcaggggccgacgctcatcgaggcgttcacgtaccgg
atgggcgcccacaccaccaccgacgaccccacccgctaccgggtggccagcgagctggag
gcgtggaagctcaaggacccgatcgagcgggtcaagtcctacctgttcaagaacgagctg
gccgaccaggcgttcttcgactccgtggacgccgaggccgaccagctcggggccgacctg
cgcaggcgctgcctggccatgcccgacccggagccgctcgacatcttcgaccacgtctac
cgcgagccccactccctgatcgaccgggagcgcgcccagttcgccgggtacttggagggg
ttccgtgactga
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