Natronobacterium gregoryi: Natgr_0994
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Entry
Natgr_0994 CDS
T02383
Name
(GenBank) AICAR transformylase/IMP cyclohydrolase PurH
KO
K01492
phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:
2.1.2.2
2.1.2.3
]
Organism
nge
Natronobacterium gregoryi
Pathway
nge00230
Purine metabolism
nge00670
One carbon pool by folate
nge01100
Metabolic pathways
nge01110
Biosynthesis of secondary metabolites
Module
nge_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nge00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Natgr_0994
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
Natgr_0994
Enzymes [BR:
nge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
Natgr_0994
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
Natgr_0994
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
Formyl_trans_N
Motif
Other DBs
NCBI-ProteinID:
AFZ72225
UniProt:
L0AGM7
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All DBs
Position
982280..983905
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AA seq
541 aa
AA seq
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MTRIAGMAGNRGRNLLNIADRRPGGAEVAVVLTTDEDAPVLEAAAERDIPTEVVPLAEEL
SRQEHETAVNDALADYEYDLVCLDGYMQILSDTFLEAQPTTLNVHPSLLPAFPGTDAWGD
ALEADVSVTGCTVHIVTDATDEDGGVIESEIDAGPVVTQEPIPVYEGDDAASLKERVLYE
GEFRAYPRAVKWFAEDAVEVDLEAGEVDLPVDRTDEDGLPARRVVSSDRVDTLRYGENPH
QDAAVYADYTCDEASVVHADQLNEGAKDLSYNNYNDADGALNLITEFDDPAAAVIKHTNP
AGCATADSLAEAYEKALSTDPQSAFGGIVALNRECDAETAEQIIDSFKEIVVAPSYTDDA
LEVLCEKDNLRVLDVGELDGEPADRFTEKPLVGGRLVQERDLQSISVDDLEVVTEREPTE
EELESMVFAWQTLKHVKSNGILFADGTETVGIGMGQVSRVDAVRLAAMKADEHAEEKDAE
GAVMASDAFFPFPDGIEEAAAAGIEAVIQPGGSVNDDDVIEAADEHGMAMAFTGQRSFRH
D
NT seq
1626 nt
NT seq
+upstream
nt +downstream
nt
atgacgcgaatcgccgggatggccggcaaccgagggcgtaacctgttgaacatcgccgac
agacgacctggtggggccgaggtcgccgtcgtcctgacgaccgacgaagacgcgccggta
ctcgaagccgccgccgagcgagacattccgaccgaagtcgtcccgctcgccgaggagttg
agccgacaagaacacgagacagctgtcaacgacgcactcgccgactacgagtacgatctg
gtctgtctcgacggctacatgcaaattctctcggacacattcctcgaggcccagccgacg
acgctgaacgtccacccgtcgctgttgcccgcgttccccggcacggacgcctggggcgac
gcactcgaggcagacgtctccgtgaccggctgtaccgtccacatcgtgacagacgcgacc
gacgaggacggtggcgtgatcgagagcgaaatcgacgcgggtccggtcgtcacccaggag
ccgattccggtctacgagggcgacgacgcggcgtcgctgaaagaacgcgtgctctacgag
ggggagttccgcgcgtacccgcgagccgtgaagtggttcgccgaggacgcagtcgaggtg
gatctcgaggcaggcgaggtcgacctgcccgtcgaccgaaccgacgaagacggccttccc
gcccggcgcgtcgtctcgagcgatcgcgtcgatacccttcgctacggcgagaacccacac
caggacgccgcggtatacgccgactacacctgcgacgaggcaagtgtcgtccacgccgac
cagttgaacgagggcgcgaaggacctctcgtacaacaactacaacgatgccgacggcgca
ctcaacctgatcacggagttcgacgaccccgccgcggcggtcatcaagcacacgaatccg
gcgggctgtgccacggccgattcgctcgccgaggcctacgagaaggctctctcgacggac
ccacagagcgccttcggcggcatcgtcgcgctaaaccgtgagtgcgatgccgagacagcc
gaacagatcatcgactcgttcaaagagatcgtcgtcgcccccagctacaccgacgacgcc
ctcgaagtgctctgcgagaaggacaacctgcgtgtactcgacgtgggggaactggacggc
gagccggccgatcgattcaccgagaaaccgctcgtcggcggccgcctcgtccaggaacgg
gacctgcagtcgatctcggtcgacgacctcgaggtcgtcaccgaacgcgagccgaccgag
gaggaactcgagtcgatggtcttcgcctggcagacactgaaacacgtcaagtcgaacggc
attctcttcgccgacggtacggagacggtcggcatcgggatgggacaggtctcccgcgtc
gacgcagtccgactggcggcgatgaaagccgacgaacacgccgaagagaaagatgccgag
ggtgcggtcatggcctcggacgccttcttcccgttcccggacggtatcgaggaagccgcg
gcggccggcatcgaagccgtaatacagcccggcggttcggtcaacgacgacgacgtgatc
gaggctgcagacgaacacgggatggcgatggcgtttacgggacagcggagtttccggcac
gactag
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