Nannospalax galili (Upper Galilee mountains blind mole rat): 103726981
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Entry
103726981 CDS
T03372
Symbol
Hk2
Name
(RefSeq) hexokinase 2
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00010
Glycolysis / Gluconeogenesis
ngi00051
Fructose and mannose metabolism
ngi00052
Galactose metabolism
ngi00500
Starch and sucrose metabolism
ngi00520
Amino sugar and nucleotide sugar metabolism
ngi00524
Neomycin, kanamycin and gentamicin biosynthesis
ngi01100
Metabolic pathways
ngi01200
Carbon metabolism
ngi01250
Biosynthesis of nucleotide sugars
ngi04066
HIF-1 signaling pathway
ngi04910
Insulin signaling pathway
ngi04930
Type II diabetes mellitus
ngi04973
Carbohydrate digestion and absorption
ngi05230
Central carbon metabolism in cancer
Module
ngi_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ngi_M00549
Nucleotide sugar biosynthesis, glucose => UDP-glucose
ngi_M00892
UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103726981 (Hk2)
00051 Fructose and mannose metabolism
103726981 (Hk2)
00052 Galactose metabolism
103726981 (Hk2)
00500 Starch and sucrose metabolism
103726981 (Hk2)
00520 Amino sugar and nucleotide sugar metabolism
103726981 (Hk2)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
103726981 (Hk2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103726981 (Hk2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103726981 (Hk2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
103726981 (Hk2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103726981 (Hk2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103726981 (Hk2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103726981 (Hk2)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
103726981 (Hk2)
Membrane trafficking [BR:
ngi04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
103726981 (Hk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
FGGY_N
Motif
Other DBs
NCBI-GeneID:
103726981
NCBI-ProteinID:
XP_008822951
UniProt:
A0A8C6W6K5
LinkDB
All DBs
Position
Un
AA seq
917 aa
AA seq
DB search
MIASHMIACLFTELNQNQVQKVDQYLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAT
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDTVEGDEGRMCINMEWGAFGDDGTLNDVRTEFDREIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFQGKLSPELLTTGSFETKDVSDIEEEKDGIRKAYQVLVRLG
LNPLQEDCVATHRVCQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKVVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLKLS
HEQLLEVKRRMKVEMEQGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGYEDPQCEVGLIVGTGSNACYMEEMRNVELVDGEEGRMCVNMEWGAFGDNGCLDD
LCTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcctcgcatatgatcgcctgcttattcacagagcttaaccaaaaccaagtgcag
aaggttgaccaatatctctaccacatgcgcctctctgatgagacccttctggagatttct
aggcggttccggaaggaaatggagaaaggtcttggagccaccacacaccctactgcaact
gtgaagatgctgcccacctttgtgaggtcaactccggatgggacagaacatggagagttc
ttagctctggaccttggagggaccaacttccgtgtgctccgagtaagagtgacagacaat
ggcctccagagggtggagatggagaaccagatctatgccatcccagaggacatcatgcgt
ggcagtggcacccagctgtttgatcacattgctgaatgcctggccaacttcatggacaag
ctacaaatcaaagaaaagaagctccccctgggctttaccttctcattcccctgccaccag
acaaagctcgatgagagtttcttggtctcatggaccaaggggttcaagtccagtggtgta
gaaggcagagatgtggtggatctgatccggaaggccatccagcgcagaggggattttgat
attgacattgtggccgtggtgaacgacacagtggggaccatgatgacctgtggttatgat
gatcagaactgtgaaatcggcctcatcgtgggcacaggaagcaatgcctgttacatggag
gagatgcgccacatcgacacggtggagggtgatgagggccggatgtgcatcaacatggag
tggggggcctttggggatgatggcacactcaatgacgtccgcaccgagtttgaccgagag
atcgacatgggctcactgaaccctgggaagcaactgtttgagaagatgattagtgggatg
tacatgggcgagctggtcaggctcatcctggtgaagatggccaaggaggagctgctcttc
caggggaagctcagcccagaactcctcaccactggctccttcgagaccaaagatgtctca
gatattgaggaggagaaagatggcatccggaaggcctaccaggtccttgtaaggctgggc
ctgaatcccttgcaggaggactgcgtggccacgcaccgcgtctgtcagatcgtgtccaca
cgctcggccagtctgtgtgcagccaccctggctgccgtgctgtggcgcatcaaggagaac
aagggcgaggagcgcctacgctccaccattggcgtcgatggctctgtctacaagaaacac
ccccactttgccaagcgtcttcacaaggtggtgaggaggctggtgcctgactgcgatgtt
cgtttcctccgctccgaggatggcagcggcaaaggggcagccatggtgacagcagtggct
taccggctggctgaccagcaccgagcccgccagaagaccctggagcctctgaagctgagc
catgagcaactgctggaggtcaagaggaggatgaaggtggaaatggagcaaggtctgagc
aaggagacacatgccattgcccctgtgaaaatgctgcccacctatgtgtgcgccacccct
gatggtacagagaaaggggacttcctggccttggacctcggaggaacgaatttccgagta
ctactggtgcgtgtgcggaatgggaagcggcggggagtggagatgcacaataagatttac
tctatccctcaggaagtcatgcatggcacaggggaggagctctttgaccacatagtccag
tgcattgctgacttcctggagtacatgggcatgaagggcgtgtccctgcctctgggtttc
accttctcattcccctgccagcagaacagcctggatgagagcatcctcctcaagtggaca
aaaggcttcaaggcatctggctgcgagggtgaagacgtggtcaccctgctgaaagaagca
attcaccggcgagaggagtttgacctggatgtggttgctgtggtgaatgacacagttgga
actatgatgacctgtggctatgaagacccacagtgtgaagttggcctcatcgttggcaca
ggcagtaatgcttgctacatggaagagatgcgcaatgtggagctggtggatggcgaggag
gggcggatgtgtgtcaacatggagtggggggcttttggggacaacggatgcctggacgac
ctctgcacggagtttgatgtggctgtggatgaactctctctcaaccctggcaaacagagg
tttgagaagatgatcagcggcatgtacctgggtgaaattgtgcgcaacattctcatagat
ttcactaaacgtggtctgctcttccgaggccgcatctcagagcgcctcaagacaagggga
atctttgaaactaagttcctgtctcagattgagagtgactgcctggccctgctacaggtc
cgagccatcctgcgccacctgggtctggagagcacgtgtgacgacagcatcatcgtcaag
gaggtgtgcaccgtggtagcacggcgagctgcccagctctgtggtgcaggcatggctgcc
gttgtggacaagatacgagaaaatcgtgggctggataccctcaaagtgacagtgggtgtg
gatgggaccctctacaagctccatccccactttgcaaaagtcatgcatgaaacagtgaag
gatctggctccaaaatgcgacgtgtccttcctggaatctgaggacggcagcgggaaggga
gcagctctcatcactgcggtggcctgccgcatccgtgaggctggacagcgatag
DBGET
integrated database retrieval system
