KEGG T03372: 103739734

Nannospalax galili (Upper Galilee mountains blind mole rat): 103739734

Entry

103739734         CDS       T03372

Symbol

Hsd17b8

Name

(RefSeq) hydroxysteroid 17-beta dehydrogenase 8

K13370

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Organism

ngi Nannospalax galili (Upper Galilee mountains blind mole rat)

Pathway

ngi00061

Fatty acid biosynthesis

ngi00140

Steroid hormone biosynthesis

ngi01100

Metabolic pathways

ngi01212

Fatty acid metabolism

Module

ngi_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:ngi00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    103739734 (Hsd17b8)
   00140 Steroid hormone biosynthesis
    103739734 (Hsd17b8)
Enzymes [BR:ngi01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     103739734 (Hsd17b8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     103739734 (Hsd17b8)

SSDB

Motif

Pfam:

adh_short_C2 adh_short KR Epimerase RmlD_sub_bind

Other DBs

NCBI-GeneID:

103739734

NCBI-ProteinID:

XP_008838433

UniProt:

A0A8C6R6E1

LinkDB

Position

AA seq 255 aa
MAAQLRLRSALALVTGAGRGIGRAVSVRLAQEGAAVAACDLDGAAALETVRLLGEHRAPG
GKHAAFQADVSQAPAARRLLEQVQACFSRPPSVVVSCAGITRDEFLLHMSEKDWDKVVAV
NLKGIYLVTQAAAQALVSSGCPGSIINISSIVGKVGNIGQTNYAASKAGVIGLTQTAARE
LGRHGIRCNSVLPGFITTSMTQKIPQKVKDKVTGMIPLGHMGDPEDVADVVAFLASEDSG
YITGASVEVTGGLFM

NT seq 768 nt +upstreamnt +downstreamnt
atggctgctcagctccggctccgctccgcgcttgccctggtcacaggtgcgggcagaggc
atcggccgcgcggtcagtgtgcgcctggctcaagagggcgctgccgtggccgcctgcgac
ctggacggggccgcggcactcgagaccgtgcggctgctgggcgagcaccgggcgcccggc
gggaagcacgccgccttccaggccgacgtgtcgcaggcccccgcggcccggcgcctgctg
gagcaagtgcaggcctgcttttctcgcccgccatctgtcgttgtgtcctgtgctggcatc
acgcgggatgagtttctgctccacatgtccgagaaagactgggacaaagtcgtagctgtc
aacctcaagggcatctacctagtcactcaggctgcagcccaggcattggtgtccagtggt
tgtcctggctccatcatcaacatcagtagcatcgttggaaaggtggggaacattgggcag
acaaactatgctgcctcgaaggcaggagtgatcgggctcacccagaccgcagcccgcgag
cttggacgacacgggatccgctgtaactcagtcctcccaggattcattacaacatccatg
acccagaaaatcccacagaaagtgaaggacaaggtgactggaatgatcccgttgggacac
atgggggaccctgaggatgtggcagatgtggttgcgttcttggcatctgaagacagtgga
tacatcacaggggcctcagtggaagtcactggaggtcttttcatgtaa

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