Nannospalax galili (Upper Galilee mountains blind mole rat): 103741428
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Entry
103741428 CDS
T03372
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00010
Glycolysis / Gluconeogenesis
ngi00020
Citrate cycle (TCA cycle)
ngi00620
Pyruvate metabolism
ngi00785
Lipoic acid metabolism
ngi01100
Metabolic pathways
ngi01200
Carbon metabolism
ngi01210
2-Oxocarboxylic acid metabolism
ngi04066
HIF-1 signaling pathway
ngi04922
Glucagon signaling pathway
ngi05230
Central carbon metabolism in cancer
ngi05415
Diabetic cardiomyopathy
Module
ngi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103741428
00020 Citrate cycle (TCA cycle)
103741428
00620 Pyruvate metabolism
103741428
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103741428
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103741428
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103741428
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103741428
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103741428
Enzymes [BR:
ngi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
103741428
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
103741428
NCBI-ProteinID:
XP_008840405
UniProt:
A0A8C6R147
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All DBs
Position
Un
AA seq
391 aa
AA seq
DB search
MRKMLAAVVSRVLFGVVQTPACRGLLASQNFSNHATCDIKRCDLYRLDDGPATSTVLTRE
DALKYYRAMQVVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAAINPSDHVITSYR
AHGLCYTRGLSVKSILAELTGRLGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGVAM
ACKYLGTGEICLALYGDGAANQGQVAEAYNLSALWKLPCVFICENNRYGMGTANERSAAS
TEYHKRGNFIPGLRVNGMDVLCVREAVRFAADYCRSGKGPIVMELQTYRFHGHSMSDPGI
SYRSREEIHDMRSKSDPVVLLREQMISNNLSNVEELKEIDTDVKREIEEAAQFATTDPEP
PLEDLANHLFTTQPPFEVRGTNKWIKYKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggcagctgtggtgtcccgcgtgttgttcggagttgtccagactcca
gcctgccgagggctgctggcctcccagaacttctcaaaccacgccacctgcgacattaag
agatgtgacctgtaccggctggacgacggcccggccacctccacggtgctcacccgggag
gacgccctcaagtactaccgcgccatgcaggtggttcgccggatggagctgaaggccgac
cagctgtacaagcagaagttcatccgtggcttctgccacctgtgcgacgggcaggaggcc
tgctgcgtggggctggaggccgccatcaacccctcggatcacgtcatcacgtcctaccgc
gctcacggcctgtgctacacgcgcggcctgtcggtcaagtccatcctggcggagctgacc
ggacgcctgggaggctgtgccaaaggcaagggcggctccatgcacatgtacgccaagaac
ttctatgggggcaacggcattgtcggggcccaggttcccctgggagccggggttgctatg
gcctgtaagtacctgggaaccggcgagatctgcctggccctgtatggcgatggcgcggcc
aaccagggccaggtggccgaggcttacaacttgtcagcgctgtggaaactgccttgcgtc
ttcatctgcgagaataaccgctacggcatggggacggcgaatgaaaggtcggcggccagc
accgagtaccacaagagaggcaacttcatccccgggctgcgcgtgaacgggatggatgtg
ctctgtgttcgcgaggcagtgaggttcgctgccgactactgccgatccggaaaggggccc
atcgtgatggagctgcagacctaccgttttcacggacacagtatgagcgacccaggcatc
agctaccgttcgcgagaagaaattcacgacatgagaagtaaaagtgatcctgttgtgctt
cttcgagagcaaatgatcagcaacaacctcagcaatgtggaagaactgaaggaaattgat
acagatgtgaaaagagaaatcgaggaagcggcccagtttgctacaactgatccagagcca
cctttggaggatttggccaatcacctcttcaccactcagccaccttttgaagttcgcggt
acaaacaagtggatcaagtacaaatctatcagttag
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