KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103748431
Entry
103748431         CDS       T03372                                 
Name
(RefSeq) cytochrome P450 11B2, mitochondrial-like
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00140  Steroid hormone biosynthesis
ngi01100  Metabolic pathways
ngi04927  Cortisol synthesis and secretion
ngi04934  Cushing syndrome
Module
ngi_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103748431
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    103748431
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103748431
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ngi00199]
    103748431
Enzymes [BR:ngi01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     103748431
Cytochrome P450 [BR:ngi00199]
 Cytochrome P450, animal type
  CYP11 family
   103748431
SSDB
Motif
Pfam: p450 Nup188_SH3-like DUF1641
Other DBs
NCBI-GeneID: 103748431
NCBI-ProteinID: XP_008849298
LinkDB
Position
Un
AA seq 500 aa
MALRTRADVWLAGGWQCLHRTRALGTTTVPVPKTVLPFEAIPQYSTNKWLKMLQIWKDQG
YENLHLEMHQAFQDLGPIFRYNTGRTQTVSVMLPEDAERLYQVDSVHPCRLPVEPWVVHR
EHRRLKLGLFLLNGPEWHFNRLRLNPKVLSPKAVEKFVPMVDTVARDFSEALKKKVLQNA
RGSLTLDIQPSIFNYTIEASNFALFGERLGLLGHDISPGSLKFIHALKSMFKSTSQLMFL
PRSLTSWTSTQVWKEHFEAWDDITEYANNRIWKVHQELRLGSHQHYSGIVAELMSKGDLP
LESIKANSIELTAGSVDTTAMPSLMTLFELARNPDVQRALRQESLAAEASISANPRRVIS
DLPLLRGALKETLRLYPVGSTVERVLSSDLVLQNYHIPAGTLVLFNLYSMGRNPAVFPRP
ERYSPQRWLDRRRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHVLRSFQVETLRQEDVRM
VYRFVLLPSSYPLLTFRPVG
NT seq 1503 nt   +upstreamnt  +downstreamnt
atggcactcaggacgagagcagatgtgtggctggcaggaggctggcagtgcttgcatagg
acaagggcactgggcaccacaacagtaccagtccccaagacggtgctgcccttcgaagcc
atacctcagtacagcaccaacaagtggctgaagatgctgcagatctggaaggatcagggc
tatgagaacctgcacctggagatgcaccaggccttccaggacctggggcccattttcagg
tataacacgggaagaacacagacagtgtctgtgatgctgccagaggatgctgagaggctg
taccaggtggatagtgtacatccctgccgattgccagtggagccctgggtggtccaccgg
gagcaccgcagactgaagctaggcctgttcctgctaaacgggcctgaatggcatttcaac
cgactgaggctgaacccaaaggtgctgtcaccaaaggctgttgaaaagtttgtccccatg
gtggacacagtggcaagggacttctcagaggccctaaagaagaaggtgctgcagaacgcc
cgtgggagcctcaccttggacattcagcccagcatcttcaactataccatagaagccagc
aactttgctctttttggagagcggctgggcctccttggccatgacataagtcctggtagc
ctgaagttcatccatgccttgaagtccatgttcaagtccacctcacagctcatgttcctg
cccaggagtctgaccagctggacaagcacccaagtgtggaaggagcactttgaggcctgg
gatgacattactgagtatgccaacaatcgcatctggaaggttcaccaggagctcagactc
ggcagccatcagcactatagtggtattgtggcagagctaatgtccaagggagatttgcca
cttgagtccatcaaggccaactccatagaactcacagctgggagtgtggacacgacagct
atgccctcgctaatgaccctctttgagctggctcggaacccggacgtgcagcgggccctg
cggcaggagagcctggcagctgaggccagcatctctgcgaatcctcggagggtcatctcg
gacttgcccctgctgcggggtgccctcaaagagactttgaggctctatcccgtgggaagc
actgtagagagagttctaagctcagacttggtgctccagaactaccacatccctgccggg
acattggtcctgtttaatctgtactcgatgggccgaaaccctgcagtgttcccgaggccc
gagcgctacagcccccagcgctggctggacaggaggagatctttccagcacctggccttt
ggctttggggtgcggcagtgcctggggcggcgcctggcagaggtggagatgctgcttctg
ctgcaccacgtgctgagatccttccaggtggagacactgaggcaagaggacgtgcggatg
gtctaccgctttgttttgttgcccagctcttatcccctcctcactttccggcctgtcggc
tag

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