Nannospalax galili (Upper Galilee mountains blind mole rat): 103749845
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Entry
103749845 CDS
T03372
Symbol
Pde2a
Name
(RefSeq) phosphodiesterase 2A
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi04022
cGMP-PKG signaling pathway
ngi04740
Olfactory transduction
ngi04925
Aldosterone synthesis and secretion
ngi05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103749845 (Pde2a)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
103749845 (Pde2a)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
103749845 (Pde2a)
09157 Sensory system
04740 Olfactory transduction
103749845 (Pde2a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103749845 (Pde2a)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
103749845 (Pde2a)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
103749845
NCBI-ProteinID:
XP_008850958
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All DBs
Position
Un
AA seq
941 aa
AA seq
DB search
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPQPCADSLQDALLSLGAIIDVA
GLRQAAKDALSAVLPRVETVYTYLLDGESRLVCEDPPHELPQEGKVREAVISQKRLSCNG
LDPSDLPGKPLARLVAPLAPDTQVLVIPLLDKEAGTVAAVILVHCGQLSDSEERSLQVVE
KHTLVALRRVQALQQRGLGAAPGAVQNSPEGSKEDQKVGEKYTDRDQKILQLCGELYDLD
ATSLQLKVLRYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLGEEISFPLTMGRLGQVV
EDKKSIQLKDLTSEDIQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKPGGDLFTD
QDEHVIQHCFYYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
ANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
QKMAEVGYDRTNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
KFTIRGLPSNNSLDFLDEEYEVPGLDGTGTPVNGCCSLEAE
NT seq
2826 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgaaccgcggggccagcaggtcttcctcaagccggacgagccgccaccaccgcag
ccatgcgccgacagcctgcaggatgctttgctgagcttgggtgccatcatcgatgttgcg
ggtctgcgacaggctgccaaggatgccctctcagctgtgctccccagagtggagactgtc
tacacctatctattggatggggagtcccggctggtttgtgaggaccccccacatgagctg
ccacaggaaggaaaagtccgagaggctgtgatttctcagaagcgactgagctgcaatgga
ctggacccctcggacctaccagggaagcccttggccaggctggtggctccgctggctcct
gacacccaagtgctggtcatacccctgctggacaaggaggctggaactgtggcagctgtg
atcttggtgcactgtggccagctgagtgacagtgaggagaggagtctgcaggtggtagag
aagcatacccttgtggccctgcggagggtgcaggccctgcagcagcgcgggctcggtgcg
gctcctggagcggttcagaattccccggaagggtccaaggaagatcagaaggttggggag
aagtacaccgaccgtgaccaaaagatcctgcaactgtgcggggaactctacgacctggat
gccacttccctgcagctcaaagtcctccgatatctgcagcaggagacccaggcatcccgc
tgctgcctcctgctagtgtcagaggacaatctgcagctttcctgcaaggtcattggagat
aaagtgctgggggaagagatcagctttcctttgaccatgggacgcctgggccaggtggtg
gaagacaagaagtccatccagctgaaggacctcacatctgaggatatacaacagctgcaa
aacatgctgggctgtgagctgcaggctatgctgtgtgttcctgtcatcagccgggccact
gaccaggtggtggccctggcctgcgcctttaacaagccgggaggagacttgttcacagac
caggatgaacatgtgatccagcactgcttctattacactggcacagtgctcactagcact
ttggccttccagaaggagcagaagctcaagtgtgagtgccaggctcttctccaagtggca
aagaacctcttcactcatttggatgatgtctctgtcctgctacaggagatcatcaccgag
gccagaaacctcagcaatgccgagatctgctccgtgttcttgctggatcagaacgaactg
gtggccaaggtgttcgacgggggcgtggtggacgatgagagctatgagatccgcatcccg
gcggaccaaggcatcgcgggccacgtggcgaccacgggacagatcctgaacatccccgac
gcgtatgcccatccgcttttctaccgcggcgtggacgacagcaccggtttccgcacgcgc
aacatcctctgtttcccgatcaagaatgagaaccaggaggtcatcggtgtggccgagctg
gtgaacaagatcaatgggccatggttcagcaagttcgatgaggacctggccacagctttc
tccatctactgcggcatcagcatcgcccattctctcctatacaagaaggtgaatgaggct
cagtatcgcagccacctggcaaatgagatgatgatgtaccacatgaaggtctctgatgat
gaatacaccaaactgctccacgatgggatccaacctgtggctgccattgattccaacttt
gccaacttcacctacactcctcgctctctgcctgaggacgacacttccatggccatcctg
agcatgctgcaggacatgaacttcatcaataactacaaaattgactgcccaactctggcc
cggttctgcttgatggtgaagaagggctaccgggatccaccctaccacaactggatgcat
gccttttctgtctcccacttctgttacctgctgtacaagaacctggagctcaccaactac
ctcgaggacatcgagatctttgccttgtttatttcctgcatgtgtcacgacctggaccac
agaggcacaaacaactccttccaggtggcctcgaaatctgtgctggctgcgctctacagc
tcagagggctctgtcatggagaggcaccactttgctcaggcaatcgccatcctcaatacc
cacggctgcaacatctttgaccacttttcccggaaggactatcagcgtatgctagacttg
atgagagacatcattttggccacagacctggcccaccacctccgaatcttcaaggacctt
cagaagatggctgaagtgggctatgacagaaccaacaagcagcaccacaggctcctcctc
tgcctcctcatgacctcctgtgatctctctgaccagaccaagggctggaagaccaccaga
aagattgcggaactcatctacaaagagttcttctcccagggagacttggaaaaggccatg
ggcaacaggccaatggagatgatggaccgggagaaagcctacatccctgagctgcagatc
agcttcatggaacacattgcaatgcccatctacaagctattgcaagacctattccccaag
gcagctgaactgtatgagcgggtggcctccaaccgtgagcactggaccaaggtgtctcac
aagttcaccatccgcggcctcccaagcaacaactcgctggacttcctggatgaggaatac
gaggtgcccggtttggatggtactgggactcctgtcaatggctgctgcagcctcgaggct
gagtga
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