Naegleria gruberi: NAEGRDRAFT_56281
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Entry
NAEGRDRAFT_56281 CDS
T01241
Name
(RefSeq) pyruvate dehydrogenase E1 alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ngr
Naegleria gruberi
Pathway
ngr00010
Glycolysis / Gluconeogenesis
ngr00020
Citrate cycle (TCA cycle)
ngr00620
Pyruvate metabolism
ngr00785
Lipoic acid metabolism
ngr01100
Metabolic pathways
ngr01110
Biosynthesis of secondary metabolites
ngr01200
Carbon metabolism
ngr01210
2-Oxocarboxylic acid metabolism
Module
ngr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ngr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NAEGRDRAFT_56281
00020 Citrate cycle (TCA cycle)
NAEGRDRAFT_56281
00620 Pyruvate metabolism
NAEGRDRAFT_56281
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NAEGRDRAFT_56281
Enzymes [BR:
ngr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NAEGRDRAFT_56281
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
PE-PPE
Motif
Other DBs
NCBI-GeneID:
8855602
NCBI-ProteinID:
XP_002673628
JGI:
Naegr1_56281
UniProt:
D2VQJ9
LinkDB
All DBs
AA seq
411 aa
AA seq
DB search
MMKKIVSGTSASRRITSVETVKKMLFAQQSRFESKVYSFNIDKEKAFKFHLPTKHMEGIN
WEGPKSEVKLTKEELIAMYRMMALIRRFELVSDQQYKARNIRGFCHLYSGQEAICVGIEH
ATNRADSVITAYRDHGFQLCRGGSVESTMAEQLGRATGCSKGKGGSMHMYKIDQNFFGGN
GIVGAQVPVGAGLAFAHSYLDRLNNKQTKDKNVTFALYGDGAANQGQIYEAFNMAKLWHI
PVIFVCENNKYGMGTSMQRSSASTDYYTRGDFIPGIWVDGMDIIAVYEAARYAKEYSQQF
GPIVLEPETYRYYGHSMSDPGISYRTRDEVNEVRNTRDPIARLKARMIEQGIATEDELKE
IDNQVKEEVQQGTEKAIAAPLPPLHELVEDVMVGPHVVRGRTVDEMYSFSK
NT seq
1236 nt
NT seq
+upstream
nt +downstream
nt
atgatgaagaaaatcgtttctggtacctctgctagcagacgtatcacttctgttgaaact
gtaaagaagatgttgttcgctcaacaaagcagatttgaatccaaagtttattcattcaat
attgataaggaaaaggctttcaagttccatctcccaaccaaacatatggaaggtattaac
tgggaaggtccaaagtctgaagttaaactcactaaggaagaattgattgccatgtaccgt
atgatggctttgattagaagatttgaattggtttctgaccaacaatacaaggctcgtaac
attcgtggtttctgccatttgtacagtggtcaagaagctatctgtgttggtattgaacat
gccaccaatcgtgctgactctgtcattactgcttatcgtgatcacggtttccaattgtgt
agaggtggttctgttgaaagcaccatggctgaacaattaggtcgtgccactggttgctca
aagggtaagggtggttctatgcacatgtacaagattgaccaaaacttctttggtggtaac
ggtattgtcggtgctcaagtcccagttggtgctggtcttgcctttgctcactcctatttg
gatagattgaataacaagcaaaccaaggataagaatgttacttttgctctctatggtgat
ggtgctgctaaccaagggcaaatctatgaagctttcaacatggccaagttgtggcacatt
ccagttatctttgtctgtgaaaacaacaagtatggtatgggtacttccatgcaacgttct
tctgcttctactgattactacactagaggtgatttcattccaggtatttgggttgatggt
atggacattattgctgtctatgaagctgctcgttatgctaaggaatattctcaacaattt
ggtccaatcgttcttgaaccagaaacttacagatattatggtcactccatgtctgatcct
ggtatttcttacagaaccagagatgaagtcaatgaagtcagaaatactagagatcctatt
gccagattgaaggctagaatgatcgaacaaggtattgctactgaagatgaattgaaggaa
attgataaccaagttaaggaagaagttcaacaaggtactgaaaaggctattgctgctcca
ctcccacctctccacgaactcgttgaagatgtcatggttggtccacacgttgtcagaggt
agaactgttgacgaaatgtactcattcagtaaataa
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