Nomascus leucogenys (northern white-cheeked gibbon): 100585467
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Entry
100585467 CDS
T03265
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X3
KO
K02085
adenomatosis polyposis coli protein
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04310
Wnt signaling pathway
nle04390
Hippo signaling pathway
nle04550
Signaling pathways regulating pluripotency of stem cells
nle04810
Regulation of actin cytoskeleton
nle04934
Cushing syndrome
nle05010
Alzheimer disease
nle05022
Pathways of neurodegeneration - multiple diseases
nle05165
Human papillomavirus infection
nle05200
Pathways in cancer
nle05206
MicroRNAs in cancer
nle05210
Colorectal cancer
nle05213
Endometrial cancer
nle05217
Basal cell carcinoma
nle05224
Breast cancer
nle05225
Hepatocellular carcinoma
nle05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100585467 (APC)
04390 Hippo signaling pathway
100585467 (APC)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100585467 (APC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100585467 (APC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100585467 (APC)
05206 MicroRNAs in cancer
100585467 (APC)
09162 Cancer: specific types
05210 Colorectal cancer
100585467 (APC)
05225 Hepatocellular carcinoma
100585467 (APC)
05226 Gastric cancer
100585467 (APC)
05217 Basal cell carcinoma
100585467 (APC)
05213 Endometrial cancer
100585467 (APC)
05224 Breast cancer
100585467 (APC)
09172 Infectious disease: viral
05165 Human papillomavirus infection
100585467 (APC)
09164 Neurodegenerative disease
05010 Alzheimer disease
100585467 (APC)
05022 Pathways of neurodegeneration - multiple diseases
100585467 (APC)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100585467 (APC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
nle01009
]
100585467 (APC)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
nle03036
]
100585467 (APC)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
nle04812
]
100585467 (APC)
Protein phosphatases and associated proteins [BR:
nle01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100585467 (APC)
Chromosome and associated proteins [BR:
nle03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
100585467 (APC)
Cytoskeleton proteins [BR:
nle04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
100585467 (APC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_u14
APC_rep
APC_u15
APC_u9
APC_N_CC
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
100585467
NCBI-ProteinID:
XP_004087472
Ensembl:
ENSNLEG00000011525
UniProt:
G1RLE9
LinkDB
All DBs
Position
2:120667465..120806975
Genome browser
AA seq
2844 aa
AA seq
DB search
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT
EAERSSQSKHETGSHDAERQNEGQGVGEINMATSGNGQGSATRVDHETASVLSSSSTHSA
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM
GSAAALRNLMANRPTKYKDANIMSPGSSVPSLHVRKQKALEAELDAQHLSETFDNIDNLS
PKASHRSKQRHKQSLYGDFVFDTNRHDDNRSDNFNAGNMTVLSPYLNTTVLPSSSSSRGS
LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQLSTTAAQIAKVMEEVSAIHTS
QEDRSSGSTTELHCVTDERNALRRSSAAHTHSSTYNFSKSENSNRTCSMPYAKLEYKRSS
NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDELKQSEQRQSRNQSTTYPVYTE
STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP
TNYSERYSEEEQHEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDIPSSQKQSFSFSKS
SSGQSTKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQTQKAATCKVSSINQETIQ
TYCVEDTPICFSRCSSLSSLSSAEDEIGCDQRTQEADSANTLQVVEIKEKIGTRSTEDPV
SEVPAVSQHTRTKSSRLQCSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF
SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE
KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS
QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ
SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKTEEGDILAECINSAMPKGKSHKP
FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN
AERVFSDNKDSKKQNLKNNSKDFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND
SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR
GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN
NNKENEPIKETEPTDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLL
QECISSAMPKKKKPSRLKGDNEKHSPRNMGGILAEDLTLDLKDIQRPDSEHGLSPDSENF
DWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPF
TSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQA
NMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVK
SELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPP
NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASK
GLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEES
ASFESLSPSSRPASPSRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYND
GRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSE
SSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEISPTNSTSQTVSSGATNGAE
SKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGNPNIKDSKD
NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTETKPGQNNPVPVSEANESSIVER
TPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSK
TDSTESNGTQSPKRHSGSYLVTSV
NT seq
8535 nt
NT seq
+upstream
nt +downstream
nt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaatcatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacaactacaaggaagtattgaagatgaagctatg
gcttcctctggacagattgatttattagagcgtcttaaagagcttaacttagatagcagt
aatttccctggagtaaaactacggtcaaaaatgtccctccgttcttatggaagccgggaa
ggatctgtatcaagccgttctggagagtgcagtcctgttcctatgggttcctttccaaga
agagggtttgtaaatggaagcagagaaagtactggatatttagaagaacttgagaaagag
aggtcattgcttcttgctgatcttgacaaagaagaaaaagaaaaagactggtattatgct
caacttcagaatctcactaaaagaatagatagtcttcctttaactgaaaatttttcctta
caaacagatatgaccagaaggcaattggagtatgaagcgaggcaaatcagagttgcaatg
gaagaacaactaggtacctgccaggatatggaaaaacgagcacagcgaagaatagccaga
attcagcaaatcgaaaaggacatacttcgtatacgacagcttttacagtcccaagcaaca
gaagcagagaggtcatctcagagcaagcatgaaaccggctcacatgatgctgagcggcag
aatgaaggtcaaggagtgggagaaatcaacatggcaacttctggtaatggtcagggttca
gctacacgagtggaccacgaaacagccagtgttttgagttctagtagcacacactctgca
cctcgaaggctgacaagtcatctgggaaccaaggtggaaatggtgtattcattgttgtca
atgcttggtactcatgataaggatgatatgtcgcgaactttgctagctatgtctagctcc
caagacagctgtatatccatgcgacagtctggatgtcttcctctcctcatccagctttta
catggcaatgacaaagactctgtattgttgggaaattcccggggcagtaaagaggctcgg
gccagggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggc
aggcgtgaaatccgagtccttcatcttttggaacagatacgcgcttactgtgaaacctgt
tgggagtggcaggaagctcatgaacaaggcatggaccaggacaaaaatccaatgccagct
cctgttgaacatcagatctgtcctgctgtgtgtgttctaatgaaactttcatttgatgaa
gagcatagacatgcaatgaatgaactagggggactacaggccattgcagaattattgcaa
gtggactgtgaaatgtatgggcttactaatgaccactacagtattacactaagacgatat
gctggaatggctttgacaaacttgactttcggagatgtagccaacaaggctacgctatgc
tctatgaaaggctgcatgagagcacttgtggcccaactaaaatctgaaagtgaagactta
cagcaggttattgcaagtgttttgaggaatttgtcttggcgagcagatgtaaatagtaag
aagacgttgcgggaagttggaagtgtgaaagcattgatggaatgtgctttagaagttaaa
aaggaatcaaccctcaaaagcgtattgagtgccttatggaatttgtcagcacattgcact
gagaataaagctgatatatgtgctgtagatggtgcacttgcatttttggttggcactctt
acttaccggagccagacaaacactttagccattattgaaagtggaggtgggatattacgg
aatgtgtccagcttgatagctacaaatgaggaccacaggcaaatcctaagagagaacaac
tgtctacaaactttattacaacacttaaaatctcatagtttgacaatagtcagtaatgca
tgtggaactttgtggaatctctcagcaagaaatcctaaagaccaggaagcattatgggac
atgggggcagttagcatgctcaagaacctcattcattcaaagcacaaaatgattgctatg
ggaagtgctgcagctttaaggaatctcatggcaaataggcctacgaagtacaaggatgcc
aatattatgtctcctggctcaagcgtgccatctcttcatgttaggaaacaaaaagcccta
gaagcagaattagatgctcagcatttatcagaaacttttgacaatatagacaatttaagt
cccaaggcatctcatcgtagtaagcaaagacacaagcaaagtctctatggtgattttgtt
tttgacaccaatcgacatgatgataataggtcagacaattttaatgctggcaacatgact
gtcctttcaccatatttgaatactacagtgttacccagctcctcttcgtcaagaggaagc
ttagatagttctcgttctgaaaaagatagaagtttggagagagaacgaggaattggtcta
ggcaactaccatccagcaacagaaaatccaggaacctcttcaaagcgaggtttgcagctc
tccaccactgcagcccagattgccaaagtcatggaagaagtgtcagccattcatacctct
caggaagacagaagttctgggtctaccactgaattacattgtgtgacagatgagagaaat
gcacttagaagaagctctgctgcccatacacattcaagcacttacaatttcagtaagtca
gaaaattcaaataggacatgttctatgccttatgccaaattagaatacaagagatcttca
aatgatagtttaaatagtgtcagtagtagtgatggttatggtaaaagaggtcaaatgaaa
ccctcaattgaatcctattctgaagatgatgaaagtaagttttgcagttatggtcaatac
ccagccgacctagcccataaaatacatagtgcaaatcatatggatgataatgatggagaa
ctagatacaccaataaattatagtcttaaatattcagatgagcagttgaactctggaagg
caaagtccttcacagaatgaaagatgggcaagacccaaacacataatagaagatgaacta
aaacaaagtgagcaaagacaatcaaggaatcaaagtacaacttaccctgtttatactgag
agcactgatgataaacacctcaagttccaaccacattttggacagcaggaatgtgtttct
ccatacagatcacggggagccaatggttcagaaacaaatcgagtgggttctaatcatgga
attaatcaaaatgtaagccagtctttgtgtcaagaagatgactatgaagatgataagcct
accaactatagtgaacgttactctgaagaagaacagcatgaagaagaagagagaccaaca
aattatagcataaaatataatgaagagaaacaccatgtggatcagcctattgattatagt
ttaaaatatgccacagatattccttcgtcacagaaacagtcattttcattctcaaagagt
tcatctggacaaagcactaaaactgaacatatgtcttcaagcagtgagaatacgtccaca
ccttcatctaatgccaagaggcagaatcagctccatccaagttctgcacagagtagaagt
ggtcagactcaaaaggctgccacttgcaaagtttcttctattaaccaagaaacaatacag
acttattgtgtagaagatactccaatatgtttttcaagatgtagttcactgtcatctttg
tcatcagctgaagatgaaataggatgtgatcagaggacacaggaagcagattctgctaac
accctgcaagtagtagaaataaaagaaaagattggaactagatcaactgaagatcctgtg
agcgaagttccagcagtgtcgcagcacactagaaccaaatccagcagactgcagtgttct
agtttatcttcagaatcagccaggcacaaagctgttgaattttcttcaggagcaaaatct
ccctccaaaagtggtgctcagacacccaaaagtccacctgaacactatgttcaggagact
ccactcatgtttagcagatgtacttctgtcagttcacttgatagttttgagagtcgttcg
attgccagctctgttcagagtgaaccgtgcagtggaatggtaagtggcattataagcccc
agtgatcttccagatagccctggacaaaccatgccaccaagcagaagtaaaacccctcca
ccacctcctcaaacagctcaaaccaagcgagaagtacctaaaaataaagcacctactgct
gaaaagagagagagtggacctaagcaagctgcagtaaatgctgcagttcagagggtccag
gttcttccagatgctgatactttattacattttgccacggaaagtactccagatggattt
tcttgttcatccagcctgagtgctctgagcctcgatgagccatttatacagaaagatgtg
gaattaagaataatgcctccagttcaggaaaatgacaatggaaatgaaacagaatcagag
cagcctaaagaatcaaatgaaaaccaagagaaagaggcagaaaaaactattgattctgaa
aaggacctattagatgattcagatgatgatgatattgaaatactagaagaatgtattatt
tctgccatgccaacaaagtcatcacgtaaagcaaaaaagccagcccagactgcttcaaaa
ttacctccacctgtggcaaggaaaccaagtcagctgcctgtgtacaaacttctaccatca
caaaacaggttgcaaccccaaaagcatgttagttttacaccgggagatgatatgccacgg
gtgtattgtgtagaagggacacctataaacttttccacagctacatctctaagtgatcta
acaatagaatcccctccaaatgagttagctgctggagaaggagttagaggaggggcacag
tcaggtgaatttgaaaaacgagataccattcctacagaaggcagaagtacagatgaagct
caaggaggaaaaacctcgtctgtaaccatacctgaattggatgacaataaaacagaggaa
ggtgatattcttgcagaatgcattaattctgctatgcccaaagggaaaagtcacaagcct
ttccgtgtgaaaaagataatggaccaggtccagcaagcatctgcgtcttcctctgcaccc
aacaaaaatcagttagatggtaagaaaaagaaaccaacttcaccagtaaaacctatacca
caaaatactgaatataggacacgtgtaagaaaaaatgcagactcgaaaaataatttaaat
gccgagagagttttctcagacaacaaagattcaaagaaacagaatttgaaaaataattcc
aaggacttcaatgataagctgccaaataatgaagatagagtcagaggaagttttgctttt
gattcacctcatcattacacacctattgaaggaactccttactgtttttcacgaaatgat
tctttgagttctctagattttgatgatgatgatgttgacctttccagggaaaaggctgag
ttaagaaaggcaaaagaaaataaggaatcagaagctaaagttaccagccacacggaacta
acctccaaccaacaatcagctaataagacacaagctattgcaaagcagccaataaatcga
ggtcagcctaaacccatacttcagaaacaatccacttttccccagtcatccaaagacata
ccagacagaggggcagcaactgatgaaaagttacagaattttgctattgaaaatactcca
gtttgcttttctcataattcctctctgagttctctcagtgacattgaccaagaaaacaac
aacaataaagaaaatgaacctatcaaagagactgagcccactgactcacagggagaacca
agtaaacctcaagcatcaggctatgctcctaaatcgtttcatgttgaagataccccagtt
tgtttctcaagaaacagttctctcagttctcttagtattgactctgaagatgacctgttg
caggaatgtataagctctgcaatgccaaaaaagaaaaagccttcaagactcaagggtgat
aatgaaaaacatagtcccagaaatatgggtggcatattagctgaagatctgacacttgat
ttgaaagatatacagagaccagattcagaacatggtctatcccctgattcagaaaatttt
gattggaaagctattcaggaaggtgcaaattccatagtaagtagtttacatcaagctgct
gctgctgcatgtttatctagacaagcttcgtctgattcagattccatcctttccctgaaa
tcaggaatctctctgggatcaccatttcatcttacacctgatcaagaagaaaaacccttt
acaagtaataaaggcccacgaattctaaaaccaggagagaaaagtacattggaaactaaa
aagatagaatctgaaagtaaaggaatcaaaggaggaaaaaaagtttataaaagtttgatt
actggaaaagttcgatctaattcagaaatttcaggccaaatgaaacagccccttcaagca
aacatgccttcaatctctcgaggcaggacaatgattcatattccaggagttcgaaatagc
tcctcaagtacaagtcctgtttctaaaaaaggcccaccccttaagactccagcctccaaa
agccctagtgaaggtcaaacggccaccacttctcctagaggagccaagccatctgtgaaa
tcagaattaagccctgttgccaggcagacatcccaaataggtgggtcaagtaaagcacct
tctagatcaggatctagagattcaaccccttcaagacctgcccagcaaccattaagtaga
cctatacagtctcctggccgaaactcaatttcccctggtagaaatggaataagtcctcct
aacaaattatctcaacttccaaggacatcatcccctagtactgcttcaactaagtcctca
ggttctggaaaaatgtcatatacatctccaggtagacagatgagccaacagaaccttacc
aaacaaacaggtttatccaagaatgccagtagtattccaagaagtgagtctgcctccaaa
ggactaaatcagatgaataatggtaatggagccaataaaaaggtagaactttctagaatg
tcttcaactaaatcaagtggaagtgaatctgatcgatcagaaagacctgtattagtacgc
cagtcaactttcatcaaagaagctccaagcccaaccttaagaagaaaattggaggaatct
gcttcatttgaatctctttctccatcatctagaccagcttctcccagtaggtcccaggca
caaactccagttttaagtccttcccttcctgatatgtctctatctacacattcatctgtt
caggctggtggatggcgaaaactcccacctaatctcagtcccactatagagtataatgat
ggaagaccagcaaagcgccatgatattgcacggtctcattctgaaagtccttctagactt
ccaatcaataggtcaggaacctggaaacgtgagcacagcaaacattcatcatcccttcct
cgagtaagcacttggagaagaactggaagttcatcttcaattctttctgcttcatcagaa
tccagtgaaaaagcaaaaagtgaggatgaaaaacatgtgaactctatttcaggaaccaaa
caaagtaaagaaaaccaagtatccgcaaagggaacatggagaaaaataaaagaaaatgaa
atttctcccacaaatagtacttctcagaccgtttcctcaggtgctacaaatggtgctgaa
tcaaagactctaatttatcaaatggcacctgctgtttctaaaacagaggatgtttgggtg
agaattgaggactgtcccattaacaatcctagatctggaagatctcccacaggtaatact
ccccctgtgattgacagtgtttcagaaaagggaaatccaaacattaaagattcaaaagat
aatcaggcaaaacaaaatgtgggtaatggcagtgttcccatgcgtaccgtgggtttggaa
aatcgcctgaactcctttattcaggtagatgcccctgaccaaaaaggaactgagacaaaa
ccaggacaaaataatcctgtccctgtatcagaggctaatgaaagttctatagtggaacgt
accccattcagttctagcagctcaagcaaacacagttcacctagtgggactgttgctgcc
agagtgactccttttaattacaacccaagccctaggaaaagcagcgcagatagcacttca
gctcggccatctcaaatcccaactccagtgaataacaacacaaagaagcgagattccaaa
actgacagcacagaatccaatggaacccaaagtcctaagcgccattctgggtcttacctt
gtgacatccgtttaa
DBGET
integrated database retrieval system
