Nomascus leucogenys (northern white-cheeked gibbon): 100588574
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Entry
100588574 CDS
T03265
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00061
Fatty acid biosynthesis
nle00620
Pyruvate metabolism
nle00640
Propanoate metabolism
nle01100
Metabolic pathways
nle01212
Fatty acid metabolism
nle04152
AMPK signaling pathway
nle04910
Insulin signaling pathway
nle04922
Glucagon signaling pathway
nle04936
Alcoholic liver disease
Module
nle_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100588574 (ACACA)
00640 Propanoate metabolism
100588574 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100588574 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100588574 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100588574 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100588574 (ACACA)
04922 Glucagon signaling pathway
100588574 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100588574 (ACACA)
Enzymes [BR:
nle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100588574 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100588574 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100588574 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
100588574
NCBI-ProteinID:
XP_030663926
Ensembl:
ENSNLEG00000002421
LinkDB
All DBs
Position
Unknown
AA seq
2346 aa
AA seq
DB search
MDEPSHLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLS
DLGISSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLQA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNIMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDSSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLV
DHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA
FLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWID
PEDPYKGYRYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGS
GMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPFLNSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVLVYIPPQAELRGGSWVVIDSSI
NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAE
RKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTE
EDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVVRILST
MDSPST
NT seq
7041 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatctcacttggccaaacctctggagctgaaccagcactctcgattcata
ataggttctgtgtctgaagataactcagaggatgagatcagcaatctggtaaagctggac
ctactggaggagaaggagggctctttgtcacctgcttctgttggctcagatacactctct
gatttggggatctctagcctacaggatggcttggccttgcacataaggtccagcatgtct
ggcttgcacctagtaaagcagggccgagacagaaagaaaatagattctcaacgagatttc
actgtggcttctccagcagaatttgttactcgctttgggggaaataaagtgattgagaag
gttcttattgctaacaatggcattgcagcagtgaaatgcatgcggtctatccgtaggtgg
tcttatgaaatgtttcgaaatgaacgtgcaattcgattcgttgtcatggtcacacctgaa
gaccttaaagccaatgcagaatacattaagatggcagatcactatgtgccagtgcctgga
ggaccaaacaacaacaactatgcaaatgtggaattaattcttgatattgctaaaaggatc
ccagtacaagcagtgtgggctggctggggtcatgcttctgagaatcccaaactaccagaa
cttctcttgaaaaatggcattgccttcatgggtcctccaagccaggccatgtgggcttta
ggggataagattgcatcttccatagtggctcaaactgcaggtatcccaactcttccctgg
agtggcagtggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatcttaaat
gttccccaggagctatatgaaaaaggttatgtgaaagatgtggatgatgggctacaggca
gctgaggaagttggatatccagtaatgatcaaggcctcagagggaggaggagggaaggga
attagaaaagtcaacaatgcagatgacttccctaatctcttcagacaggttcaagctgaa
gttcctggatctcccatatttgtgatgagactagccaaacaatctcgtcatctggaggtg
cagatcttagcagaccaatatggcaatgctatctctttgtttggtcgtgattgctctgta
caacgcaggcatcagaagattattgaagaagcccctgctactattgctactccagcagta
tttgaacacatggaacagtgtgcggtgaaacttgccaaaatggtgggttatgtgagtgct
gggactgtggaatacctgtacagccaggatggcagcttctactttctggaattgaatcct
cggctacaggtagagcacccttgtacagagatggtggctgatgtcaatctccctgcagca
cagctccagattgccatggggattcctctatatagaatcaaggatatccgtatgatgtac
ggggtatctccctggggtgattctcccattgattttgaagattctgcacacgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaggaactaaatttccgcagcaataagaatgtttggggatat
ttcagtgttgctgctgcagggggacttcatgaatttgctgattctcagtttggtcactgc
ttttcttggggagaaaacagagaggaggcaatttcaaacatggtggtggctttgaaggag
ctgtctattcggggtgactttcgaactacagttgaatacctgatcaaattgttagagact
gaaagctttcagatgaacagaattgatactggctggctggacagactgatagcagaaaaa
gtacaggctgagcgacctgacaccatgttgggggttgtgtgtggggccctccacgtggca
gatgtgagcctgcggaatagcatctctaacttccttcactccttagaaaggggtcaagtt
cttcctgctcatacacttctgaatacagtagatgttgaacttatctatgagggagtcaag
tatgtacttaaggtgactcgacagtcccccaactcctatgtggtgatcatgaatggctca
tgtgtagaagtagatgtacatcggctgagtgacggtggactgctcttgtcctatgatggc
agcagttatactacgtatatgaaagaggaagtggatagatatcgcatcacgattggcaat
aaaacctgtgtgtttgagaaggaaaatgacccatcagtgatgcgctcaccttctgctggg
aagttaatccagtacattgtagaagatggaggtcatgtgtttgctggccagtgctatgct
gagattgaggtgatgaagatggtaatgaccttaacagctgtggagtctggctgtatccat
tacgtcaagcgacctggagcagctcttgaccctggctgtgtactagccaaaatgcaactg
gacaaccctagcaaggttcagcaggctgaacttcacacaggtagtctgccacggatccag
agcacggcactcagaggcgagaaactccatcgagtgttccattatgtcctggataatctg
gtcaacataatgaatggatactgccttccagatcctttctttagcagcaaggtaaaagac
tgggtagagcgattgatgaaaaccctcagagatccctccctgcctctcctagaattgcaa
gatatcatgaccagtgtgtctggccgcattccccccaatgtggagaagtctatcaagaag
gaaatggctcagtatgctagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctagatagccatgcagctacattgaaccggaaatctgaacgagaagtc
ttctttatgaatactcagagcattgttcagctggtacagaggtaccgaagtggcatccga
ggccacatgaaggctgtggtgatggatctgctccggcagtacctgcgagtagagacgcaa
ttccagaatggtcactatgacaaatgtgtattcgccctccgggaagagaataaaagtgac
atgaacactgtactgaactacatcttctctcacgctcaagtcaccaagaagaatcttctg
gtcacaatgcttattgatcagttgtgtggccgagaccctactctcactgatgagcttctg
aatattctcacagagctaactcaactcagtaagaccaccaatgccaaagtagcacttcga
gcacgccaggttcttattgcctcccatttgccatcatatgagcttcgccataaccaagta
gagtctatcttcctatcagctattgacatgtatggacatcaattttgcattgagaacctg
cagaaactcatcctatcagaaacatctatttttgatgtcctaccaaacttcttctatcac
agcaaccaagtagtgaggatggcagctctggaggtgtatgttcgaagggcttatattgcc
tacgaacttaacagcgtacaacaccgccagcttaaggacaacacctgtgtggtggaattc
cagttcatgctgcccacatctcatccaaacagagggaacatccctacgctaaacagaatg
tccttctcctccaacctcaaccactacggcatgacccatgtggctagtgtcagcgatgta
ctgttggacagctcattcactccaccttgtcagcggatgggcggaatggtctcttttcgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctctgactcccca
ccccagagtcccacattccctgaggcgggtcacacatctctttatgatgaagataaggtt
cccagggatgaaccaattcacattctcaatgtggctatcaagactgactgtgatattgag
gatgacaggctggcagctatgttcagagaatttacccagcaaaataaagctaccctggtt
gaccatgggatccggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtc
aactatgaggtggatcggagatttcatagagaattccctaaattttttacattccgagca
agggataagtttgaggaggatcgtatctatcgtcacctggaacctgctctggctttccag
ttagagctgaaccggatgagaaattttgacctcactgccattccatgtgctaatcacaag
atgcacctgtatctcggggcagccaaggtggaagtgggtacagaagtgacagactacagg
ttctttgttcgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcttttgaa
tatctgcaaaatgaaggggagcggctactcctggaagccatggatgagttggaagttgct
tttaacaatacaaatgtccgtactgactgtaaccacatcttcctcaactttgtgcccacg
gttatcatggacccgtcaaagattgaggaatctgtgcggagcatggtaatgcggtatgga
agtcgcctgtggaaattgcgtgtcctgcaggcagaactgaaaatcaacattcgcctgacg
ccaactggaaaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttg
gatatcagcctatacaaggaagtgactgactccaggacagcacagatcatgtttcaggca
tatggagacaaacagggaccactgcatggaatgttaatcaatactccttatgtgaccaaa
gacctgctgcaatcaaagaggttccaggcgcaatccttagggacaacatacatatatgat
atcccagagatgtttcggcagtccctgatcaaactctgggagtctatgtccactcaagca
tttcttccatctccccctctgccttctgacatgctgacttacaccgaactggtattggat
gatcaaggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgacctttaaaagtcctgaatatccagaaggccgagatatcattgttatt
ggcaatgacatcacataccgaattgggtcctttgggcctcaagaggatttgttatttctc
agagcttctgaacttgctagggcagaaggtattccacgcatctatgtatcagccaacagt
ggagcaagaatcggactggcagaagaaattcgtcatatgtttcatgtggcctggatagat
cctgaggatccttacaagggatacagatatttatatctgacccctcaagattataagaga
gtcagtgctctcaactctgtccattgtgaacacgtggaggatgaaggagaatccaggtac
aagataacagatattattgggaaagaagagggaattggacccgagaaccttcgaggttct
ggaatgattgctggagaatcctcattggcctataatgagatcattaccatcagcctggtg
acgtgccgggccattgggattggggcttaccttgtccggctgggacagagaaccatccag
gttgagaattctcacttaattctaacaggagctggagccctcaacaaagttcttgggcgg
gaagtgtatacctccaataaccagctggggggcatccagattatgcacaacaatggggtg
acccactgcactgtgtgtgatgactttgaaggggttttcactgtcctgcactggctgtct
tacatgcccaagagcgtgcacagttcagttccttttctgaactcaaaggatcctatagac
agaatcatcgagtttgttcccacaaaggccccatacgatcctcgatggatgctagcaggc
cgtcctcacccaacccaaaaaggtcaatggttgagtggcttttttgactatggatctttc
tcagagattatgcagccctgggcacagactgtggtggttggtagagccaggctaggagga
atacctgtgggagttgttgctgtagaaacccgaacagtagaactaagtatcccagctgat
ccagcaaacctggattctgaagccaagataatccagcaggctggccaggtttggttccca
gattctgcgtttaagacatatcaggccatcaaggacttcaacagggaagggctgcctctg
atggtctttgccaactggagaggcttctctggtggaatgaaagacatgtacgaccaagtg
ctgaagtttggtgcttacattgtggacggcttgagggagtgctcccagcctgtgctggtt
tacattcctccccaggctgagctgcggggtggctcctgggtagtgattgactcctccatc
aacccccggcacatggagatgtatgctgaccgagaaagcaggggatctgttctggagcca
gaagggacagtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtg
gatccagtctacatccacttggctgagcgattggggaccccagagctaagcacggctgag
cggaaggagttggagaacaagttgaaggagcgggaggaattcctaattcccatttaccat
caggtagccgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggt
gttattagcgatatcctggattggaaaacatcccgtaccttcttctactggcggctgagg
cgtcttctgctggaggacctggtcaagaagaaaatccacaatgccaaccctgagctgact
gacggccagattcaagccatgttaaggcgctggtttgtggaagtggaaggaacagtgaag
gcctatgtttgggacaataataaggatctggcggagtggctagagaaacagctgacagag
gaggatggtgttcactcggtaatagaggaaaacatcaaatgcatcagcagagactacgtc
ctcaagcaaatccgcagcttggtccaggccaatccagaggttgccatggattccatcatc
catatgacccagcatatatcacccactcagcgagcagaagtcgtacggatcctctccaca
atggattccccttccacgtag
DBGET
integrated database retrieval system
