Nomascus leucogenys (northern white-cheeked gibbon): 100590035
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Entry
100590035 CDS
T03265
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X1
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00120
Primary bile acid biosynthesis
nle01040
Biosynthesis of unsaturated fatty acids
nle01100
Metabolic pathways
nle01212
Fatty acid metabolism
nle04146
Peroxisome
Module
nle_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
nle_M00861
beta-Oxidation, peroxisome, VLCFA
nle_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
100590035 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
100590035 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100590035 (HSD17B4)
Enzymes [BR:
nle01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
100590035 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
100590035 (HSD17B4)
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Gene cluster
GFIT
Motif
Pfam:
adh_short
MaoC_dehydratas
adh_short_C2
SCP2
KR
Alkyl_sulf_C
MaoC_dehydrat_N
AbrB-like
Motif
Other DBs
NCBI-GeneID:
100590035
NCBI-ProteinID:
XP_030674040
Ensembl:
ENSNLEG00000011926
LinkDB
All DBs
Position
2:127446260..127534968
Genome browser
AA seq
763 aa
AA seq
DB search
MGSPLRFDGRVVVVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
RVHLRGSFQVTRAAWEHMRKQKYGRIIMTSSASGIYGNFGQANYGAAKLGLLGLANSLAI
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
KIDSEGGVSANHTSRATSIATSGFAGAIGQKLPPFSYVYTELEAIMYALGVGASIKDPKD
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
AVAIPNRPPDAVLTDTTSLNQAVVTVFHPDIILGFPFYIFFSLLLILVAALYRLSGDWNP
LHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTL
QTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPSEGGKLQSTLVFEEIGR
RLKDVGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDE
DFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atgggctcaccgctgaggttcgacggccgggtggtagtggtcaccggcgctggggcagga
ttgggccgagcctatgccctggcttttgcagaaagaggagcgttagttgttgtgaatgat
ttgggaggggacttcaaaggagttggtaaaggctccttagctgctgataaggttgttgaa
gaaataagaaggagaggtggaaaagcagtggccaactatgattcagtggaagaaggagag
aaggttgtgaagacagccctggatgcttttggaagaatagatgttgtggtcaacaatgct
ggaattctgagggatcgttcctttgctaggataagtgatgaagactgggatataatccac
agagttcatttgcggggttcattccaagtgacacgggcagcatgggaacacatgaggaaa
cagaaatatggaaggattattatgacttcatcagcttcaggaatatatggcaactttggc
caggccaattatggtgctgcaaagttgggtcttctgggccttgcaaattctcttgcaatt
gaaggcaggaaaagcaacattcattgtaacaccattgctcctaatgcgggatcacggatg
actcagacagttatgcctgaagatctcgtggaagccctgaagccagagtatgtggcaccc
cttgtcctttggctttgtcacgagagttgtgaggagaatggtggcttgtttgaggttgga
gcaggatggattggaaaattacgctgggagcggactcttggagctattgtaagacaaaag
aatcacccaatgactcctgaggcagtcaaggctaactggaagaagatctgtgactttgag
aatgccagcaagcctcagagtatccaagaatcaactggcagtataattgaagttctgagt
aaaatagattcagaaggaggagtttcagcaaatcatactagtcgtgcaacgtctatagca
acatcaggatttgctggagctattggccagaaactccctccattttcttatgtttatacg
gaactggaagctattatgtatgcccttggagtgggagcatcaatcaaggatccaaaagat
ttgaaatttatttatgaaggaagttctgatttctcctgtttgcccaccttcggagttatc
ataggtcagaaatctatgatgggtggaggattagcagaaattcctggactttcaatcaac
tttgcaaaggttcttcatggagagcagtacttagagttatataaaccacttcccagagca
ggaaaattaaaatgtgaagcagttgttgctgatgtcctagataaaggatccggtgtagtg
attattatggatgtgtattcttattctgagaaggaacttatatgccacaatcagttctct
ctctttcttgttggctctggaggctttggtggaaaacggacatcagacaaagtcaaggta
gctgtagccatacctaatagacctcctgatgctgtacttacggataccacctctcttaat
caggcagtagtaacagtgtttcacccagatataattcttggcttccccttctacattttt
ttttccctcctactgattttagtggctgctttgtaccgcctcagtggagactggaatccc
ttacacatcgatcctaactttgctagtctagcaggttttgacaagcccatattacatgga
ttatgtacattcggattttctgccaggcgtgttttacagcagtttgcagataatgatgtg
tcaagattcaaggcaattaaggctcgttttgcaaagccagtatatccaggacaaactcta
caaactgagatgtggaaggaaggaaacagaattcattttcaaaccaaggtccaagaaact
ggagacattgtcatttcaaatgcatatgtggatcttgcaccaacatctgatacttcagct
aagacaccctctgagggcgggaagcttcagagtactctcgtatttgaggaaataggacgc
cgcctaaaggatgttgggcctgaggtggtgaagaaagtaaatgctgtatttgagtggcat
ataaccaaaggcggaaatattggggctaagtggactattgacctgaaaagtggttctgga
aaagtgtaccaaggccctgcaaaaggagctgctgatacaacaatcatactttcagatgaa
gatttcatggaggtggtcctgggcaagcttgaccctcagaaggcattctttagtggcaga
ctgaaggccagagggaacatcatgctgagccagaaacttcagatgattcttaaagactat
gccaagctctga
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