Nomascus leucogenys (northern white-cheeked gibbon): 100595000
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Entry
100595000 CDS
T03265
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00010
Glycolysis / Gluconeogenesis
nle00020
Citrate cycle (TCA cycle)
nle00620
Pyruvate metabolism
nle00785
Lipoic acid metabolism
nle01100
Metabolic pathways
nle01200
Carbon metabolism
nle01210
2-Oxocarboxylic acid metabolism
nle04066
HIF-1 signaling pathway
nle04922
Glucagon signaling pathway
nle05230
Central carbon metabolism in cancer
nle05415
Diabetic cardiomyopathy
Module
nle_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100595000 (PDHA2)
00020 Citrate cycle (TCA cycle)
100595000 (PDHA2)
00620 Pyruvate metabolism
100595000 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100595000 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100595000 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100595000 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100595000 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100595000 (PDHA2)
Enzymes [BR:
nle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100595000 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100595000
NCBI-ProteinID:
XP_003257567
Ensembl:
ENSNLEG00000018620
LinkDB
All DBs
Position
9:78367267..78368649
Genome browser
AA seq
391 aa
AA seq
DB search
MKNMLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKQCDLYLLEEGPPVTTVLTRA
EGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYR
AHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNDEICLTLYGDGAANQGQMAEAFNMAALWKLPCVFICENNLYAMGTSTERAAAS
SDYYKRGNFIPGLKVDGMDVLCVREATKFAADYCRSGKGPILMELQTYRFHGHSMSDPGV
SYRTREEIQEVRSKRDPIMILQDRIVSSKLATVEELKEIGTEVRKEIDDASQFATTDIEP
HLEELGHHIYSSDSSFEVRGANPWIKFKSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaatatgctggctgccttcatctcccgcgtgttgaggcgagttgcccagaaatca
gctcgcagagtgctggtggcatcccgtaactcctcaaatgacgctacatttgaaattaag
caatgtgatctttatctgttggaagagggtccccctgtcactacagtgctcactagggcg
gaggggcttaaatactacaggatgatgctgactgttcgccgcatggaattgaaggcagat
cagctgtacaaacagaaattcattcgcggtttctgtcacctgtgtgatggtcaggaagcc
tgctgcgtgggccttgaggccggcataaacccctcggaccacgtcatcacatcatatagg
gctcatggtgtgtgctatactcgggggctttctgtccgatccattctcgcagagctgacg
ggaagaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtataccaagaac
ttctacgggggcaatggcatcgtcggtgcgcagggccccctgggcgctggcattgctctg
gcctgtaaatataaaggaaacgatgagatctgtttgactttatatggggatggggctgcg
aatcaggggcagatggccgaagctttcaatatggcagctttatggaaattaccttgtgtt
ttcatctgtgagaataacctatatgcaatgggaacatctactgagagagcagcagccagc
tctgattactacaagaggggcaattttatccctgggctaaaggtcgatggaatggatgtt
ctgtgtgttcgtgaggcaacaaaatttgcagccgactactgtagatctggaaaggggccc
atactgatggagctgcagacctaccgttttcatggacacagtatgagtgatcctggagtc
agttatcgtacacgagaagaaattcaggaagtaagaagtaagagggatcctataatgatt
ctccaagatagaattgtaagcagcaagctcgccactgtggaagaattaaaggaaattggg
actgaggtgaggaaagaaattgatgatgcttcccagtttgctaccactgatattgagcca
catttggaagaattaggccatcacatctacagcagtgattcatcttttgaagttcgtggt
gcaaatccatggatcaagtttaagtccgtcagttaa
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