Neisseria meningitidis G2136 (serogroup B): NMBG2136_1242
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Entry
NMBG2136_1242 CDS
T01929
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
nmd
Neisseria meningitidis G2136 (serogroup B)
Pathway
nmd00010
Glycolysis / Gluconeogenesis
nmd00020
Citrate cycle (TCA cycle)
nmd00620
Pyruvate metabolism
nmd00785
Lipoic acid metabolism
nmd01100
Metabolic pathways
nmd01110
Biosynthesis of secondary metabolites
nmd01120
Microbial metabolism in diverse environments
nmd01200
Carbon metabolism
nmd01210
2-Oxocarboxylic acid metabolism
Module
nmd_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nmd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NMBG2136_1242 (aceE)
00020 Citrate cycle (TCA cycle)
NMBG2136_1242 (aceE)
00620 Pyruvate metabolism
NMBG2136_1242 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NMBG2136_1242 (aceE)
Enzymes [BR:
nmd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NMBG2136_1242 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADY93943
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Position
1267207..1269870
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AA seq
887 aa
AA seq
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MSTQLHDVDPIETQEWLDALSSVLEYEGGERAQYLLENLVKYCRDKGVRMPHGTTTPYLN
TVSVENEKGIPGDQNIEHRIRAFVRWNAAAIVLRAGKKDLELGGHIASFQSAATMYEVGF
NHFWKAKGEGEEGDLVFFQGHVAPGIYARAFVEGRLTEDQLNNFRQEVDGHGLPSYPHPH
LLPDFWQFPTVSMGLGPIMAIYQARFLKYLESRGLAKTKGRKVWCFCGDGEMDEPESQGA
IALAAREGLDNLIFVINCNLQRLDGPVRGNGKIIQELEGNFAGAGWNVVKVIWGRRWDRL
LAKDKDGILRQRMEECLDGDYQTYKSKDGAYVREHFFNTPELKTLVADMTDEQLWALNRG
GHDPQKVYNAYDRAANHADGKPTVILAKTIKGYGMGASGEGQNVAHQAKKMDKASLKQFR
DRFDIPVTDEQIESGDLPYLTFAPDTEEYKYLHARRDALGGYLPQRKPTQEVLEVPELSA
FDAQLKSSGEREFSTTMAFVRILSTLLKDKKIGKRVVPIVPDESRTFGMEGMFRQYGIWN
PKGQQYTPQDKDQLMFYKESVDGQILQEGINEPGAMADWIAAATSYANSNFAMIPFYIYY
SMFGFQRVGDLAWAAGDMHARGFLLGGTAGRTTLNGEGLQHEDGHSHIQADLIPNCVSYD
PTFQYEVAVIVQDGLRRMYANNEDVFYYITLMNENYTHPDMPEGAEQDILKGMYLLKAGG
KGDKKVQLMGSGTILQEVIAGAELLKADFGVEADIWSCPSFNLLHRDAVEVERFNRLHPL
EAEKVPFVTSKLQGHDGPVIAATDYIRSYADRIRAYIPNDYHVLGTDGFGRSDSRANLRR
FFEVDRYNVAVAALSALAEQGKVSKETVQQAIEKYGIKADSAPSWKR
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtccacccaattacacgatgttgaccctatcgaaacccaagagtggctggacgcgtta
agctccgtcctcgaatatgaaggcggcgaacgcgcgcaatacctcttggaaaacctggtc
aaatactgccgcgacaagggcgtacgtatgccacacggcacgaccacaccgtatttgaat
accgtttcggttgaaaacgaaaaaggcattccgggcgaccaaaacatcgaacaccgcatc
cgcgcattcgtgcgctggaacgccgccgccatcgtattgcgcgccggcaagaaagatttg
gaactgggtgggcacatcgcatctttccaatctgccgccaccatgtacgaagtcggtttc
aaccacttttggaaagccaaaggcgaaggcgaagaaggcgatttggtcttcttccaaggt
cacgtcgccccgggcatctatgcacgcgcattcgtcgagggccgtctgaccgaagaccag
ctgaacaacttccgccaagaagtggacggacacggtctgccttcctatccgcacccccac
ctcttgcccgacttttggcagttcccgaccgtatccatgggcttggggcccatcatggcg
atttatcaggcgcgtttcctgaaatacttggaatcgcgtggtttggcaaaaaccaaaggc
cgtaaagtatggtgtttctgcggcgacggcgaaatggacgaacccgaatctcaaggtgca
atcgcactggctgcacgcgaaggcttggacaacctgattttcgtcatcaactgcaatctg
caacgcttggacggtccggtacgcggcaacggcaaaatcatccaagaattggaaggcaac
tttgccggcgccggctggaatgtcgtcaaagtcatttggggccgccgctgggaccgcctc
ttggcgaaagacaaagacggtatcctgcgccaacgtatggaagaatgtttggacggcgac
taccaaacttacaaatccaaagacggcgcgtatgtgcgcgaacacttcttcaatacgccc
gaactgaaaacattggttgccgatatgaccgatgagcaactctgggcattgaaccgcggc
ggccacgacccgcaaaaagtgtacaacgcctacgaccgcgcagcgaaccatgccgacggc
aaacctaccgtcatcttggcgaaaaccattaaaggttacggtatgggcgcatccggcgaa
ggtcagaacgttgcccaccaagccaaaaaaatggacaaagcgtccctgaaacaattccgc
gaccgctttgacattccggttaccgacgaacaaatcgaaagcggcgatctgccttacctg
acttttgcccccgatacggaagaatacaaatacctgcacgcacgccgcgatgctttgggt
ggctacctgccgcaacgcaaaccgacgcaggaagtattggaagtgcccgagctgtcagca
ttcgacgcacaactcaaatccagcggtgaacgcgagttctcgaccacgatggcattcgtc
cgcatcctgtccactttgctgaaagacaaaaaaatcggcaaacgcgtcgtacctatcgtt
cccgacgaaagccgtactttcggcatggaaggtatgttccgccaatacggtatttggaat
ccgaaaggtcagcaatatacccctcaagacaaagaccaactgatgttctataaagaatcc
gttgacggtcaaatcttgcaagaaggtattaacgaaccgggcgcgatggccgactggatt
gcggctgcaaccagctacgccaacagcaacttcgcgatgattccgttctacatttactat
tctatgttcggtttccaacgtgtcggcgacttggcatgggcagccggtgatatgcacgcg
cgcggcttcctgctgggcggtactgccggccgtacgacgctgaacggcgaaggcctgcaa
cacgaagacggccacagccacatccaggccgacctgattccgaactgcgtatcttatgac
ccgactttccaatacgaagtcgccgtcatcgtacaagacggtctgcgccgtatgtatgcc
aataatgaagacgtgttctactacatcaccctgatgaacgagaactacacccatccggat
atgcccgaaggtgcggaacaagacatcctgaaaggtatgtatctgctgaaagccggcggc
aaaggcgacaagaaagttcaattgatgggctccggtaccatcctgcaagaagtcattgcc
ggtgccgagctgctgaaagccgacttcggcgtagaagcagacatctggtcttgcccgtcc
ttcaacctgctgcaccgcgacgctgtcgaggtagaacgcttcaaccgcctgcatccgctg
gaagccgaaaaagtacctttcgttacttccaaattgcaaggtcatgacggtccggttatt
gccgctaccgactatatccgcagctatgctgaccgtatccgcgcctacatcccgaacgac
taccacgtcttgggtactgacggcttcggccgctccgacagccgcgccaacctgcgccgc
ttctttgaagtggatcgctacaacgttgccgtggcagcattgagcgcattggcggaacaa
ggcaaagtcagcaaagaaaccgttcaacaagccattgagaaatacggcatcaaagccgat
tcagctcctagctggaaacgctga
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