Neisseria meningitidis MC58 (serogroup B): NMB0693
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Entry
NMB0693 CDS
T00027
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nme
Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00790
Folate biosynthesis
nme01100
Metabolic pathways
nme01240
Biosynthesis of cofactors
Module
nme_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nme00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NMB0693 (folC)
Enzymes [BR:
nme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NMB0693 (folC)
6.3.2.17 tetrahydrofolate synthase
NMB0693 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AAF41110
UniProt:
Q9K0C1
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Position
complement(719490..720764)
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AA seq
424 aa
AA seq
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MKTLQDWLSHLETAHSGGLIDMGLERTSEVKKRMKLEPQCPVVVVAGTNGKGSVCAYLTQ
IYKQAGYKIGTLTSPHLLRYNERIAINAEPVSDDTIIASFERIEAARGEISLTYFEFNAL
AAVDIFMREQVDVMILEVGLGGRLDAVNAFDGDCAVVTSVDLDHQAFLGDTVEQVGFEKA
GVFRSGKPAICGQNPAPKSLLSHAEAIGAKLLMVQRDFEFHAMENIQWNYRFRPQHSDDP
ARNRNALPFPALRGTYQLSNAACALTVLECLNDKLPVDIGAIKRGLLLVENPGRFQVLPG
RPLTVLDVGHNPHAARALRRSLINLAFAQKRTAVFSMLSDKDIDGVLETVKDQFDEWYIA
PLDVPRGMTLESLQNKLHEHSIENIQTFAAVREAYRAAASKAGENDRIVVFGSFHTVADV
MSVL
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacactacaagactggctctcgcatttggaaaccgcccacagcggcggtttgatc
gacatgggtttggagcgcacgagcgaagtgaaaaaacgcatgaagctcgagccgcaatgc
cccgtcgtcgttgtcgcgggaaccaacggcaaaggttcggtctgtgcctacctgacacag
atttacaaacaggcgggctacaaaatcggtacgctgaccagcccgcatttattgcgttac
aacgaacgcatcgccatcaacgccgaacccgtttcggacgatacgattattgcctctttc
gagcgcatcgaagccgcgcgcggcgaaatatcactgacttattttgaattcaatgccttg
gcggctgtcgacatcttcatgcgcgaacaggttgacgtgatgatattggaagtcggcttg
ggcggccgcttggacgcggtcaacgcgtttgacggcgattgcgcggtggttaccagcgtg
gatttggaccatcaggcatttttgggcgatacggtcgagcaggtcggctttgaaaaagca
ggcgtgttccgtagcggcaaacccgccatctgcggtcaaaaccccgcgcccaaatcgttg
ctttcacacgccgaagccataggcgcgaaactgctgatggtgcagcgcgatttcgagttt
cacgcgatggaaaacatccaatggaactaccgcttccggccgcaacattcagacgacccc
gcgcgcaaccgcaatgccctgcccttccccgcattgcgcggcacataccagctttccaat
gccgcctgcgcgctgaccgtattggaatgcttgaacgacaaattgccggtggacatcggt
gccatcaagcgcggtttgttgctggttgaaaatcccggacgcttccaagtcctgcccggc
cggccgctgaccgttttggatgtcggacacaatccccacgccgcccgcgccctgcgccgc
agcctgattaatttggcgtttgcgcaaaaacgcaccgccgtgttcagcatgttgtccgac
aaagacatagacggcgtgttggaaaccgttaaagaccagtttgacgagtggtatatcgca
ccgttggatgtaccgcgcggcatgacgctcgagagcctgcaaaacaaactgcacgaacac
agcatcgaaaacatacaaacattcgccgccgtccgcgaagcataccgggcggcagcctca
aaagcgggcgagaacgacagaatcgtcgttttcggctcatttcataccgttgccgatgtc
atgtcggtactttaa
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