Nyctereutes procyonoides (raccoon dog): 129502672 Help Entry 129502672         CDS       T09008                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo00230   Purine metabolism npo01100   Metabolic pathways npo01522   Endocrine resistance npo04015   Rap1 signaling pathway npo04020   Calcium signaling pathway npo04022   cGMP-PKG signaling pathway npo04024   cAMP signaling pathway npo04062   Chemokine signaling pathway npo04072   Phospholipase D signaling pathway npo04114   Oocyte meiosis npo04211   Longevity regulating pathway npo04213   Longevity regulating pathway - multiple species npo04261   Adrenergic signaling in cardiomyocytes npo04270   Vascular smooth muscle contraction npo04371   Apelin signaling pathway npo04540   Gap junction npo04611   Platelet activation npo04713   Circadian entrainment npo04714   Thermogenesis npo04720   Long-term potentiation npo04723   Retrograde endocannabinoid signaling npo04724   Glutamatergic synapse npo04725   Cholinergic synapse npo04727   GABAergic synapse npo04742   Taste transduction npo04750   Inflammatory mediator regulation of TRP channels npo04911   Insulin secretion npo04912   GnRH signaling pathway npo04913   Ovarian steroidogenesis npo04914   Progesterone-mediated oocyte maturation npo04915   Estrogen signaling pathway npo04916   Melanogenesis npo04918   Thyroid hormone synthesis npo04921   Oxytocin signaling pathway npo04923   Regulation of lipolysis in adipocytes npo04925   Aldosterone synthesis and secretion npo04926   Relaxin signaling pathway npo04927   Cortisol synthesis and secretion npo04928   Parathyroid hormone synthesis, secretion and action npo04934   Cushing syndrome npo04935   Growth hormone synthesis, secretion and action npo04970   Salivary secretion npo04971   Gastric acid secretion npo04972   Pancreatic secretion npo04976   Bile secretion npo05032   Morphine addiction npo05163   Human cytomegalovirus infection npo05166   Human T-cell leukemia virus 1 infection npo05200   Pathways in cancer npo05207   Chemical carcinogenesis - receptor activation npo05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:npo00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     129502672 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     129502672 (ADCY8)    04371 Apelin signaling pathway     129502672 (ADCY8)    04020 Calcium signaling pathway     129502672 (ADCY8)    04072 Phospholipase D signaling pathway     129502672 (ADCY8)    04024 cAMP signaling pathway     129502672 (ADCY8)    04022 cGMP-PKG signaling pathway     129502672 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     129502672 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     129502672 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     129502672 (ADCY8)    04062 Chemokine signaling pathway     129502672 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     129502672 (ADCY8)    04923 Regulation of lipolysis in adipocytes     129502672 (ADCY8)    04912 GnRH signaling pathway     129502672 (ADCY8)    04913 Ovarian steroidogenesis     129502672 (ADCY8)    04915 Estrogen signaling pathway     129502672 (ADCY8)    04914 Progesterone-mediated oocyte maturation     129502672 (ADCY8)    04921 Oxytocin signaling pathway     129502672 (ADCY8)    04926 Relaxin signaling pathway     129502672 (ADCY8)    04935 Growth hormone synthesis, secretion and action     129502672 (ADCY8)    04918 Thyroid hormone synthesis     129502672 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     129502672 (ADCY8)    04916 Melanogenesis     129502672 (ADCY8)    04925 Aldosterone synthesis and secretion     129502672 (ADCY8)    04927 Cortisol synthesis and secretion     129502672 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     129502672 (ADCY8)    04270 Vascular smooth muscle contraction     129502672 (ADCY8)   09154 Digestive system    04970 Salivary secretion     129502672 (ADCY8)    04971 Gastric acid secretion     129502672 (ADCY8)    04972 Pancreatic secretion     129502672 (ADCY8)    04976 Bile secretion     129502672 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     129502672 (ADCY8)    04727 GABAergic synapse     129502672 (ADCY8)    04725 Cholinergic synapse     129502672 (ADCY8)    04720 Long-term potentiation     129502672 (ADCY8)    04723 Retrograde endocannabinoid signaling     129502672 (ADCY8)   09157 Sensory system    04742 Taste transduction     129502672 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     129502672 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     129502672 (ADCY8)    04213 Longevity regulating pathway - multiple species     129502672 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     129502672 (ADCY8)    04714 Thermogenesis     129502672 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129502672 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     129502672 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129502672 (ADCY8)    05163 Human cytomegalovirus infection     129502672 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     129502672 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     129502672 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     129502672 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     129502672 (ADCY8) Enzymes [BR:npo01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      129502672 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  129502672 NCBI-ProteinID:  XP_055170425 LinkDB All DBs Position Unknown AA seq 1262 aa AA seqDB search MELSEVRCLGGSEELYTIHPTPPAGDGGGSARPQRLLWQTAVRHITEQRFIHGHRGGGGG GGGGGGSRGSGKAAAPAGGGPNHPAAQRCGDAALPLYSLGPGERAHGTGGTKVFPERSGS GSGRGSGGGGGSGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERL YQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICAL VVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPL TWAILAGLGTSLLQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQA FLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHR YENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVS GLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDV WSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQ PEESLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINL LPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRD EVFKSNLVCAFILLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPL VLRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDI CSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNH SGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNEN MLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLR LLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLA LTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGR IQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQ YSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAQAEGTDKSD LP NT seq 3789 nt NT seq  +upstreamnt  +downstreamnt atggagctctcggaggtgcgctgcctgggcggcagcgaggagctctacaccatccacccg acgcccccggccggcgacggcggcggcagcgctcggccgcagcggctgctatggcaaacg gcggtgcggcacatcaccgagcagcgcttcatccacgggcaccggggcggcggcggcggc ggcggcggcggcggcgggagcagaggctcgggcaaagccgcggcccctgcgggcggcggc cccaaccaccccgcggcgcagcggtgcggagacgcggcgctgccgctctactcgctgggc cccggggagagggcgcacggcaccgggggcaccaaagtcttcccggagcgcagcggcagc ggcagcggcaggggcagcggcggcggcggcggcagcggcggcgggggcgacctgggcttc ctgcacctcgactgcgccccgagcaactcggatttcttcctcagcggcggctacagctac cgaggggtcattttccccactctgcgcaactctttcaagtcccgggatctggagcgcctc taccagcgctatttcctgggccagaggcgcaaatccgaagtggtgatgaacgtgctggac gtgctgaccaaactcaccctcttggtcctccacttgagcctggcctcggcccccatggac ccgctcaagggcatcctcctgggcttcttcacgggcatcgaggtggtgatctgcgccctg gtggtggtcaggaaggacaccacctcgcacacgtacctgcagtacagcggtgtggtcact tgggtggccatgaccacccagatcttggcagcaggcctcggctatgggcttctgggtgat ggcatcggctacgtcctcttcacgctgttcgccacctacagcatgctgccactgccgctc acctgggccatcctggccggcctgggcacctcgctgctgcaggtggtcctgcaggtggtc atcccccggctggcggtcatttccatcaaccaggtggtggcccaggcggtgttattcatg tgtatgaacacggctggaatctttatcagttacctgtcagatcgggcccagcgccaagcc ttcctagagactcggaggtgtgtggaggccaggctgcgcctggagacagaaaaccagaga caggaacggctcgttctatctgtgcttcctcggtttgtcgtcctggaaatgatcaatgac atgaccaatgttgaagacgaacacttgcagcaccagttccatcggatctacatccatcgt tacgagaatgtcagtattctttttgcagatgttaaaggatttaccaacctctccacgacc ttatccgcccaggagctggtcaggatgctcaacgagctctttgccagatttgatcgactg gcccatgagcatcactgccttcgcattaaaatcctgggggactgttactactgtgtttca gggcttcctgagccccgccaggaccacgcccactgctgcgttgaaatgggcctcagcatg atcaaaaccatcaggtatgtgaggtcaaggacaaagcatgatgttgacatgcggatcgga atccactcgggctcggtgctgtgtggagtgttgggcctacggaagtggcagtttgatgtc tggtcttgggatgtggacattgcgaacaaacttgaatctggaggaatccccgggaggatt cacatttccaaagccacgctggactgcctcaacggtgactataatgtggaagagggtcat gggaaagaaagaaacgaattcttgaggaagcataatatagagacctatttgattaagcag cctgaggagagtctgctgtcgttgcccgaagacattgtcaaggagtcggtgagctcctca gacaggagaaacagtggggcgacgttcacagaaggatcctggagccccgaactgcccttt gataacatagtggggaaacagaatactctggctgccctaacaagaaattcaataaatcta cttccaaaccatcttgcacaagctttgcatgtccagtctgggcctgaggaaattaacaag agaatagaacataccatcgacttgcggagtggcgataaattgagaagagagcatatcaag ccattctcactgatgtttaaagactccagcctggagcacaagtattctcaaatgagggat gaagtattcaagtcaaacttggtgtgtgcatttatccttcttctgtttatcacggccata caaagtttgcttccttcttcaagggtgatgccaatggccatccagttttccatcctgatt atgctgcattcggctctggtcctcatcacgacagcagaggattataagtgtttgcccctt gtcctccggaagacatgctgttggattaacgagacctatttggcccggaatgtcatcatc tttgcatccatcctgattaacttcctgggcgccatcctgaatattctgtggtgtgatttt gacaagtcgatacccttgaagaacctgactttcaattcctcagctgtgtttacagatatc tgctcctacccagagtactttgtcttcactggggtgttggccatggtgacctgtgcagtg ttcctccgcctaaactctgtcctgaagctggctgtgctgctgattatgattgccatctac gccctgctgactgagaccatctatgcaggcctctttctgcgctacgacaacctgaaccac agtggagaagattttctggggaccaaggaggcatcgctgctgctaatggccatgtttctc cttgctgtgttttaccacggacagcagctggagtacacagcccgccttgacttcctttgg cgagtacaggccaaagaggagatcaacgagatgaaagagctaagagaacacaatgagaac atgctccggaacattctacccagccacgtagcccgccacttcctggagaaagaccgggac aacgaggagctgtattctcaatcctatgatgccgtcggggtgatgttcgcctccatcccc gggtttgctgacttttactctcagactgaaatgaataaccaaggagtggaatgcctgcgc ctgctgaatgagatcattgctgacttcgatgagctgctcggtgaagaccggtttcaagac attgaaaagatcaagacaattggcagcacctacatggctgtgtcaggcctgtcacctgaa aaacagcaatgtgaagacaagtggggccatttgtgtgccctggccgacttctccctcgcc ctgactgagagcatacaggagatcaacaagcattccttcaacaattttgaactccggatt ggcatcagccacggctcggtggtagctggcgtcatcggcgcaaagaagccacagtatgac atttggggcaaaaccgtgaatctggcgagtcgaatggacagcacgggggtcagtggcagg atccaagtccccgaggagacctatcttatcctgaaggatcagggctttgcctttgactac cgaggggagatctacgtgaagggcatcagtgaacaggaaggaaagatcaaaacgtacttt ctgctgggaagagtccaacccaacccattcatcctgcctccgagaagattgcccgggcag tactccctggccgcggtggtcctgggcctggtccagtccctcaacaggcaaaggcagaag cagcttctcaatgagaacaacaacacggggattatcaagggtcattacaaccggcggact ttgttgacacccagcggaccagagcctggagcccaagctgaaggcaccgacaagtccgat ttgccataa

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