Neomonachus schauinslandi (Hawaiian monk seal): 110570364
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Entry
110570364 CDS
T08474
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04140
Autophagy - animal
nsu04141
Protein processing in endoplasmic reticulum
nsu04210
Apoptosis
nsu04932
Non-alcoholic fatty liver disease
nsu05010
Alzheimer disease
nsu05012
Parkinson disease
nsu05014
Amyotrophic lateral sclerosis
nsu05016
Huntington disease
nsu05017
Spinocerebellar ataxia
nsu05022
Pathways of neurodegeneration - multiple diseases
nsu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
110570364 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110570364 (ERN1)
09143 Cell growth and death
04210 Apoptosis
110570364 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110570364 (ERN1)
05012 Parkinson disease
110570364 (ERN1)
05014 Amyotrophic lateral sclerosis
110570364 (ERN1)
05016 Huntington disease
110570364 (ERN1)
05017 Spinocerebellar ataxia
110570364 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
110570364 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110570364 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110570364 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110570364 (ERN1)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110570364 (ERN1)
Protein kinases [BR:
nsu01001
]
Serine/threonine kinases: Other
IRE family
110570364 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Pkinase_fungal
Kdo
PQQ_2
PQQ
Motif
Other DBs
NCBI-GeneID:
110570364
NCBI-ProteinID:
XP_021534049
EnsemblRapid:
ENSNSCG00000017740
UniProt:
A0A2Y9G8F7
LinkDB
All DBs
Position
15:complement(45283461..45358959)
Genome browser
AA seq
857 aa
AA seq
DB search
MGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNA
TYFDYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGL
KKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASP
SMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRN
YWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTT
ISQDVEEKYEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQ
QFQKELEKIQLLQQQLPFHPPGDMAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHST
GSASKAGTSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRTKAMISDFGLCKKLAV
GRHSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQ
RQANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCGHERLFQPY
YFHEPPGPRPPLTPDTL
NT seq
2574 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaaaagcaggacatttggtacgttattgaccttctgaccggggagaagcagcag
actctgtcatcggcctttgcagacagcctctgcccttcaacctctctgctgtatcttggg
cgaacggagtacaccatcaccatgtacgacaccaaaacccgtgagctccggtggaacgcc
acctacttcgactacgcagcctctctgcccgaggacgacggggactacaagatgtcccac
tttgtgtccaacggcgacgggctggtggtgaccgtggacagtgaatccggcgacgtcctg
tggatccaaaactacgcttcccccgtggtggccttttatgtttggcagagggagggtctg
aagaaggtgatgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtct
ggggaggtgggccgcatcaccaagtggaagtacccgttccccaaggagacggaggccaag
agcaagctgacgcccaccctgtatgttgggaaatactctaccagcctgtatgcctccccc
tccatggttcacgagggggtcgccgttgtgccccgaggcagcactcttcctttgctggaa
ggcccccaaaccgacggggtcaccattggggacaaaggggagtgtgtgatcacgcccagc
acagacctcaagtttgaccctgggctcaaagggaagaacaagctcaactacctgaggaac
tactggcttctgatcggacaccatgaaacccccctgtctgcgtctaccaagatgctggag
agattccccaacaacctgcccaaacatcgggaaaacgtgattcctgccgattcagagaag
aagagctttgaggaagttatcaacctggttgaccagacttcagaaaacgcgcctaccacc
atctcacaggatgtggaagagaaatacgagcatgcccctgccaagcccgaggcccccgtg
gactccatgctcaaggatattgccaccatcatcctgagcaccttcctgctcatcggctgg
gtggccttcatcatcacctaccccttgagcatgcatcagcagcagcagctccagcaccag
cagttccagaaggaactagagaaaatccagctcctacaacagcagctgcccttccatcca
cctggagacatggctcaagatgctgagctcttggactcgtccggcctgtactccgagagc
tcaggcaccagcagccccagcacgtcccccagagcctccaaccactcgctgcactccact
ggctcagcctccaaggctggcaccagccccttcctggagcaggacgatgaggatgaggaa
accagcatggtgatcgttgggaagatttcattctgtcccaaggacgtgctgggtcacgga
gctgagggcacaattgtgtaccggggcatgtttgacaaccgcgatgtggccgtcaagagg
atcctcccggagtgtttcagttttgcggaccgcgaagttcagctgcttcgagaatcagat
gagcaccccaacgtgatccgttacttctgcacagagagggaccggcagttccagtacatt
gccatcgagctgtgtgcagccaccctgcaggagtacgtggagcagaaggactttgcccac
ctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccacctgcac
tccctcaacattgttcacagagacctgaagccccacaacattctcctctccatgcccaac
gcacatggcaggaccaaggccatgatctcggacttcggtctctgcaagaagctggcggta
ggccggcacagtttcagccgccgctcaggagttccgggcacggaaggctggatcgctcca
gagatgttgagcgaagactgcaaggacaacccgacctacacagtggacatcttctctgca
ggctgtgtcttttactacgtgatctcggagggcagccacccttttggcaagtccctgcag
cggcaggccaacatcctcctgggtgcctacagccttgactgcttgcaccccgagaagcac
gaagatgtcattgcccgggaattaatagagaagatgattgcgatggatcctcagaaacgc
ccgtccgcgaagcacgtgctgaaacatccgttcttctggagcctggaaaagcagctccag
ttctttcaggacgtgagtgaccgaatagaaaaggagtccctggacggcccgatagtgaag
cagctggagcgaggcgggagagctgtggtgaagatggactggagggaaaacatcaccgtc
cccctgcagacagatctgcggaaattcagaacctataaaggtggctctgttcgagacctc
ctccgagccatgagaaacaagaagcaccactaccgggagctccccgtggaggtgcgggag
acgctgggctccctccctgacgacttcgtgcgctacttcacgtcccgcttcccccacctc
ctctcccacacctaccgggccatggagccgtgcggccacgagcggctcttccagccctac
tacttccacgagcccccagggccccggcctccattgactccagacaccctttga
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