Neomonachus schauinslandi (Hawaiian monk seal): 110572122
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Entry
110572122 CDS
T08474
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00010
Glycolysis / Gluconeogenesis
nsu00020
Citrate cycle (TCA cycle)
nsu00620
Pyruvate metabolism
nsu00785
Lipoic acid metabolism
nsu01100
Metabolic pathways
nsu01200
Carbon metabolism
nsu01210
2-Oxocarboxylic acid metabolism
nsu04066
HIF-1 signaling pathway
nsu04922
Glucagon signaling pathway
nsu05230
Central carbon metabolism in cancer
nsu05415
Diabetic cardiomyopathy
Module
nsu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110572122 (PDHA2)
00020 Citrate cycle (TCA cycle)
110572122 (PDHA2)
00620 Pyruvate metabolism
110572122 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110572122 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110572122 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110572122 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110572122 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110572122 (PDHA2)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110572122 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
110572122
NCBI-ProteinID:
XP_021536067
EnsemblRapid:
ENSNSCG00000020009
UniProt:
A0A2Y9GAS0
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All DBs
Position
2:complement(125190224..125191399)
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AA seq
391 aa
AA seq
DB search
MKKMLAAAVSRVLSGVAQKPASRVLVASCNYSNDATFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGKKEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFVCENNLYGMGTSAERAAAS
TDYYKRGHFIPGLRVDGMDVLCVREATRFAADYCRSEKGPIVMELQTYRYHGHSMSDPGV
SYRTRQEIQNVRSKSDPIMLLKDRMVNSKLATVEEFKEIDVEVRKEINDAAHFATTDPEP
PLEELGHHIYWDNPPFEVRGASQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgccgccgcggtctcccgcgtgttgtccggggttgcccagaagccc
gctagcagagtgctggtggcatcctgtaactattccaatgatgccacatttgaaattaag
aaatgtgacctttatcgattagaagagggcccccctgtcacaacagtgctcacccgggag
gatgggcttaaatactacaggatgatgcagactattcgccgaatggaattgaaggcagat
cagctgtataaacaaaaatttattcgtgggttctgtcacttgtgcgatggtcaggaagct
tgttgtgtgggcctggaggccgggataaatcccactgatcatgtcatcacatcctatcgg
gctcacggcttgtgctatactcgtggactttctgtccgagcaattcttgcagaactgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggatctatgcatatgtatgcaaagaac
ttctatgggggcaacggcattgtcggcgcccaggggcccctgggagctggtgtcgccctg
gcctgtaaatataagggcaaaaaggaggtctgtttgaccctgtatggggatggtgctgcg
aatcagggtcagatatttgaagcttacaatatggctgctctgtggaaattaccttgtgtt
ttcgtctgtgagaataacctctatggaatgggcacgtctgctgagagagcagcagcaagc
actgattactataagagaggacactttatccccggactaagggtggatggaatggatgtt
ctgtgtgttcgggaggcaacgaggtttgccgcggactactgtagatctgaaaaggggccc
atagtgatggagctgcagacataccgttatcatggacacagcatgagtgaccccggagtt
agttaccgcacgcgacaagaaattcagaatgtaagaagtaagagtgatcctattatgctt
ctcaaagatagaatggtaaacagtaagcttgccactgttgaagaattcaaggaaattgat
gtagaagtgaggaaagaaattaacgatgcagcccactttgctacaactgatcctgaacca
cctttggaagaattaggtcatcacatctattgggataatccaccttttgaagttcgtggt
gcaagtcagtggatcaagtttaagtccctcagttaa
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