Neomonachus schauinslandi (Hawaiian monk seal): 110587338
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Entry
110587338 CDS
T08474
Symbol
TPO
Name
(RefSeq) LOW QUALITY PROTEIN: thyroid peroxidase
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00350
Tyrosine metabolism
nsu01100
Metabolic pathways
nsu04918
Thyroid hormone synthesis
nsu05320
Autoimmune thyroid disease
Module
nsu_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
110587338 (TPO)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
110587338 (TPO)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
110587338 (TPO)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
110587338 (TPO)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
EGF_CA
EGF_3
cEGF
FXa_inhibition
Sushi
Plasmod_Pvs28
Motif
Other DBs
NCBI-GeneID:
110587338
NCBI-ProteinID:
XP_021553252
UniProt:
A0A2Y9HNT2
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All DBs
Position
10:815667..859819
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AA seq
940 aa
AA seq
DB search
MRALAVLGVTLVAACTHSFFPFLLRGKDLLWGRNRDSPVISIVEASRRMVDSAIYHTMKR
DLSKREIPRPSQLLSFSKLPEPTSRAIARAAEIMEASMQALKTSVSGKLGRSWPPTDVLP
EDVLNTIANVSGCLPYMLPPKCPDTCLTSKYRLITGACNNRDHPRWGASNTALARWLPPA
YEDGVSEPRGWNPHLRYNGFPLPPVREVTRQVIQVPNEAVTEDDQYSDLLMVWGQYIDHD
IAFTPQSTSKAAFGGGADCQLTCENQNPCFPIQLPSNASGTAGGACLPFYRSSAACGSGI
QGAFFGNLTLANPRQQMNGLTSFLDASTVYGSSPASEKQLRNWTSAEGLLRVNTRYGDTG
RAYLPFTRPPAPTACAPEPGPRGTAGAPCFLAGDGRASEVPALTAVHTLWLREHNRLASA
LKALNTHWSADTTYQEARKVVGALHQIITMRDYVPKVLGPEAFQQHVGPYEGYDPAVDPT
VSNVFSTAAFRFGHATVHPLVRRLDARFQEHPGLPPLRLQDAFFSPWRLLKEGGLDPLVR
GLLARPAKLQVQDQLMNEELTERLFVLGSSGRLDLASINLQRGRDHGLPGYNAWREFCGL
PRLETWADLRTAMANASIAGRIMDLYGHPDNIDVWLGGLAETFLPQARTGPLFACLIGRQ
MKALRDGDRFWWESSGVFTEAQRRELARHSLSRVICDNTGLPSVPTDAFQIGRFPRDFES
CENIPGLNLDMWKEALPQGDACSLPDGVDNGGFALCGESGRRVLVFSCRHGFRLQGQEQV
ACSPRGADPQPPVCRDINECEDVTHPPCHPSARCRNTKGSFRCECTDPYVLGEDGRTCVD
SGRLPKASLVSIVLGALLVGGLAGLTWTAVCRWTLTGRKASLPIAETDGRGTCQPGRGAR
RDMMCCSLVPPLRAQGRTRPVDPKSFSASRNHSGVLGGRA
NT seq
2823 nt
NT seq
+upstream
nt +downstream
nt
atgagagcgctcgcggtcctgggcgtcacactggtggcggcctgcacacacagcttcttc
cccttcctcctgagaggcaaggacctcctgtggggacggaacagagactctcctgtcatc
agcatcgtggaagcgagcaggcgcatggtggacagcgccatctaccacaccatgaagagg
gacctcagcaaaagagagatccctcgtccatcacagcttctgtctttttccaaactccct
gagccaaccagccgagccattgcccgagcggccgagatcatggaagcttccatgcaggcc
ctgaagacaagcgtctccgggaagctcgggcgatcttggcctcccaccgacgtcctgccg
gaagatgtgctgaacacaattgcgaacgtgtccggatgcctgccctacatgctacccccc
aaatgtccagacacctgcctgaccagcaagtacagactcatcacgggcgcttgcaacaac
agagaccaccccaggtggggagcctccaacacagccctggcgcgatggcttccgcccgcc
tacgaagacggggtcagtgagcccagaggctggaacccccacttgcggtacaacggcttc
ccactgcccccggtccgggaggtgacaagacaagtcattcaagttcccaacgaggccgtc
acagaggatgaccaatattctgatctcctgatggtgtgggggcaatatattgatcacgac
attgcgttcacacctcagagcaccagcaaagctgcatttgggggaggagctgattgccag
ctgacctgtgaaaaccaaaacccatgtttccccatacagctgcccagcaacgcctcgggg
actgcaggtggcgcctgtttgccattttaccgctcctctgccgcctgtggctccgggatc
caaggcgccttctttggcaacctgaccttggccaacccgcgacagcagatgaacgggctg
acctcgttcctggacgcgtccacggtgtatggcagctccccggcctcggagaagcagctg
cgcaactggaccagcgccgaggggctgctccgggtcaacacgcgctacggggacacgggc
cgcgcctacctgcccttcacgcggccgcccgcgcccacggcctgcgcgcctgagcccggc
ccccgcgggacggccggagcgccctgcttcctggcgggggacggccgtgccagcgaggtc
cccgctctgacagccgtgcacacgctctggctgcgtgagcacaaccgcctggcgtccgcg
ctcaaggctctcaacacgcactggagtgccgacaccacctaccaggaggcgcgcaaggtg
gtgggcgccctgcaccagatcattaccatgcgagactatgttcccaaagtcctgggccct
gaggccttccagcagcacgtgggcccctatgagggctacgaccccgctgtggaccccacc
gtgtccaatgtgttttccacggccgccttccgcttcggccacgccacggtgcacccgctg
gtgaggcggctggacgcccgcttccaggagcaccccggccttccccctctgcggctgcag
gacgccttcttcagcccgtggaggcttctcaaggaaggtggtttggaccccctggtgagg
ggccttctcgcgagaccagccaagctgcaggtgcaggaccagctgatgaacgaggagctg
acggagaggctgttcgtgctggggagctcgggcaggctggacctggcgtccatcaacctg
caacgcggccgggaccacggcctgccaggctacaatgcgtggagggagttctgcggcctg
cccagactggagacgtgggccgacctgcgcaccgccatggccaacgcgagcattgccggc
cggataatggacctgtatgggcaccccgacaacatcgacgtctggctgggcggcctggcc
gagaccttcctcccccaggcccgcacgggtccgctgtttgcatgcctcattgggaggcag
atgaaggccctgcgggacggggatcggttctggtgggagagcagcggggtgttcaccgag
gcccagcggcgcgagctggcgaggcattccctgtcccgggtcatctgtgacaacacgggc
ctccccagcgtgcccactgacgccttccagatcgggagattcccgcgggactttgagtca
tgcgagaacattccgggtctgaacctggacatgtggaaggaggcccttcctcaaggggac
gcgtgcagcctcccggacggcgtggacaacgggggcttcgcgctctgtggcgagtctggg
cggcgcgtgctcgtgttctcctgccgccatgggttccggctgcaaggccaggagcaggtg
gcctgctccccccgcggcgcggatccccagccccctgtctgcagagatatcaacgagtgt
gaagacgtcacacaccctccctgccatccgtcggcccggtgcaggaacaccaagggcagc
ttcaggtgtgagtgcacggatccctacgtgctgggggaggacggaaggacatgtgtagac
tccgggaggctcccgaaggcgtccctggtctccatcgtgttgggcgctctgttggtcggc
ggcctggcaggcctcacctggacggcggtttgccggtggacgctcacgggccgtaaagcc
tcactgcccatcgcggagacagatggaagagggacctgccagccgggccgtggagcacgc
cgggacatgatgtgctgcagcctggtgcccccactccgggcgcagggcaggacccggcct
gtggatcccaaatccttctctgccagtaggaaccacagtggtgtgcttggaggccgggcg
tga
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