Neomonachus schauinslandi (Hawaiian monk seal): 110592813
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Entry
110592813 CDS
T08474
Symbol
NOS2
Name
(RefSeq) LOW QUALITY PROTEIN: nitric oxide synthase, inducible
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00220
Arginine biosynthesis
nsu00330
Arginine and proline metabolism
nsu01100
Metabolic pathways
nsu04020
Calcium signaling pathway
nsu04066
HIF-1 signaling pathway
nsu04146
Peroxisome
nsu04371
Apelin signaling pathway
nsu04926
Relaxin signaling pathway
nsu05010
Alzheimer disease
nsu05014
Amyotrophic lateral sclerosis
nsu05022
Pathways of neurodegeneration - multiple diseases
nsu05133
Pertussis
nsu05140
Leishmaniasis
nsu05142
Chagas disease
nsu05145
Toxoplasmosis
nsu05146
Amoebiasis
nsu05152
Tuberculosis
nsu05200
Pathways in cancer
nsu05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
110592813 (NOS2)
00330 Arginine and proline metabolism
110592813 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
110592813 (NOS2)
04066 HIF-1 signaling pathway
110592813 (NOS2)
04020 Calcium signaling pathway
110592813 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
110592813 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
110592813 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110592813 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
110592813 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
110592813 (NOS2)
05152 Tuberculosis
110592813 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
110592813 (NOS2)
05145 Toxoplasmosis
110592813 (NOS2)
05140 Leishmaniasis
110592813 (NOS2)
05142 Chagas disease
110592813 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
110592813 (NOS2)
05014 Amyotrophic lateral sclerosis
110592813 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
110592813 (NOS2)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
110592813 (NOS2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
110592813
NCBI-ProteinID:
XP_021559634
EnsemblRapid:
ENSNSCG00000019471
UniProt:
A0A2Y9IBE4
LinkDB
All DBs
Position
15:18370347..18406673
Genome browser
AA seq
1157 aa
AA seq
DB search
MACPWQFLFKARAYRFDLTKETDINNNVGKASQVPSSLVTQDDPKYHGLGKHRNESPQSL
TGTVKTSPESLIKLDAPPSVCPRHVRIKNWGSGMTFQDTLHHKAKGYLACKSKSCLGAIM
NPKSLTRGPRDKPTPPDELLPQAIEFVNHYYSSFKEAKIEEHLARVEAVTKEIETTGTYL
LTADELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAKEMFEHICRHLRYATNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYG
RFDVVPLVLQADGQDPEFFEIPPDLVLEVPMEHPKYEWFRELQLKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEINV
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFYYYQVEAWKTHTWQDEKRRPRRRKIPFKVLVKAVLFTSMLMRRTMASRVRAT
ILFATETGKSEMLARDLGALFSCAFNPKVLCMDEYKLSHLEEEQLLLVVTSTFGNGDSPG
NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACEMFNVRGKHSVQIPKLYTCNVTWDPQHYRLVQDSRPLDL
NKALSSMHAKNVFTLRLKSQRNLQSPQSSRTTLLVELSCEDSCGLSYMPGEHLGVCPGNQ
PALVRGILERVVDGPAPHQPVHLETLSESGSYWVRDKRLPPCSLSQALTYFLDITTPPTQ
VLLRRLAHLATEEAERQRLKTLCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL
PILKPRYYSISSSRDRTPTEVHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCF
LRSAGNFQLPEDPSHPCILIGPGTGIAPFRGFWQQRLHDTKHKGLQAGRMTLVFGCRRPD
EDHLYQEEMLEMAQNGVLHEVHTAYSRLPGQPKVYVQDILQQQLASEVLRVLHEEHGHLY
VCGDVRMARDVAHTLKLLVAAKLSLSEEQVEDYFFQLKSQKRYHEDIFGSVFPYVVKKDG
AARQPSDPRVPAAHGSS
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtccctggcagttcttgttcaaggccagagcctaccggttcgacttgaccaag
gaaacagacatcaacaacaatgtggggaaagccagccaggtcccctccagtctagtgaca
caggatgaccccaagtatcatggcctcggcaagcaccggaatgagtccccccagtccctc
acagggacggtcaagacgtctccagaatccctgatcaaactggatgcgcccccatcggtc
tgcccgcgacatgtgaggatcaaaaactggggcagtgggatgaccttccaagacacactt
caccacaaggccaaagggtatcttgcttgcaagtccaagtcttgtctgggagccatcatg
aaccccaaaagtttgaccagaggacccagggacaagcctacccccccagacgagctccta
cctcaagctattgaatttgtcaaccactattacagctccttcaaagaggcaaaaatagag
gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctatctg
ctgacggcggatgagctcatctttgctaccaagcaggcctggcgcaacgccccccgctgc
atcgggaggatccagtggtccaacctgcaggtctttgatgcccggagctgttccactgcc
aaggaaatgttcgagcacatctgcagacacctgcgttatgccaccaacaacggcaacatc
aggtcggccatcactgtgttcccccagcggagcgatgggaagcatgacttccgggtctgg
aatgctcagctcatccggtatgccggctaccagatgccggacggcaccatcctgggggac
cccgccagcgtggagttcactcagctgtgcatcgacctgggctggaagcccaagtacggc
cgcttcgatgtggtgcccctggtgctacaggcggatggccaggaccctgagttctttgaa
attccgcctgaccttgtgctcgaggtgcccatggaacatcccaagtatgagtggttccgt
gagctgcagctgaagtggtacgccctgcctgcagtggccaacatgctgctcgaggtgggt
ggcctcgagttcccagggtgccccttcaacggctggtacatgggcacggagatcggggtc
cgggacttctgtgacgttcagcgctacaacattctggaggaagtgggcagaaggatgggc
ctggaaacgcacaagctggcctcactctggaaggaccgggctgtcattgagatcaatgtt
gctgtgctccacagcttccagaagcagaatgtgaccatcatggaccaccactcagctgca
gagtccttcatgaagtacatgcagaacgagtaccgctcccgagggggctgcccggctgac
tggatttggctggtccccccgatttctgggagcatcactcctgtgttccaccaggagatg
ttaaactatgtcctgtcccctttctactactaccaggtggaggcctggaaaacccacacc
tggcaggacgagaagcggagaccccggagaagaaagattccgttcaaagtcttggttaaa
gctgtgctcttcacctccatgctgatgcgcaggaccatggcgtcccgagtcagggccaca
atcctctttgcgacggagacaggaaagtctgaaatgctggcccgggacctgggggccttg
ttcagctgtgccttcaaccccaaggtcctctgcatggacgagtacaagctgagtcatctg
gaggaggagcagctgcttctggtggtgaccagcacgtttgggaatggagactcgcccggc
aatggagagaaactgaaaaaatctctcttcatgctgaaagagcttaccaacaagttcagg
tatgctgtgttcggcctcggctccagcatgtaccctcagttctgtgcctttgctcatgac
atcgaccagaagctgtcccatctgggggcctctcagctcgccccaacaggggagggggac
gagctcagtggacaggaggaagccttccgcagctgggccgtgcagaccttcaaggcagcc
tgtgagatgttcaatgtgcgaggcaaacacagcgttcagatccccaagctctacacctgc
aatgtgacctgggacccacagcactacaggctcgtgcaggactcgcggcctctggacctc
aacaaagccctcagcagtatgcacgccaagaacgtgttcaccctgaggctcaaatcacaa
cggaatctacagagtccccaatccagccgcaccaccctcctggtggagctttcctgtgag
gacagctgcgggctgagctacatgcccggagagcacctcggggtttgcccgggcaaccag
ccagccctggtgcgaggcatcttggagcgagtggtagatggccctgcaccccaccagcct
gtgcacctggagacgctcagtgagagtggaagctattgggtcagagacaagcggctgccc
ccgtgctcactcagccaggccctcacctacttcctggacatcaccaccccccctacccag
gtgctgctccgaaggctggcacacctggccacggaagaggccgagaggcagaggctgaag
accctgtgccagccctcagaatacaacaagtggaagttcaccaacagccccacattcctg
gaggtgctagaggagttcccatccctgcgggtgtctgctggcttcctactctcccagctc
cctattctgaaaccccggtactactccatcagctcctccagggaccgcacacccacggag
gtccacctcacggtggctgtgctcacctaccgcacccgagatggccaaggtcccttgcac
catggtgtctgtagcacatggctcagcagcctgaagccccaagacccagtaccctgcttc
ctgagaagtgccggcaacttccagctccctgaggacccctcccatccttgcatcctcatc
ggacctggcacaggcattgcccccttccgtggtttctggcagcagcggctccatgacacc
aagcacaaagggctccaggccggccgcatgaccctggtgttcgggtgccgccgcccagat
gaggaccacctgtatcaggaggagatgttggagatggcccagaatggagtgctgcatgag
gtgcacacagcctattctcgcctgcctggccagcccaaggtctatgttcaagacatcctg
cagcagcagctggccagtgaggtgctccgcgtgctccatgaggagcatggccacctttat
gtctgtggggatgtgcgtatggcccgggatgtggcccataccctgaagctcctggtggct
gccaagctgagcctgagtgaggagcaggtggaggactattttttccagcttaagagccag
aagcgctatcatgaggatatctttggctctgtgtttccctatgtggtgaaaaaagatggg
gcagcaaggcagcccagcgatcccagagttccagcagcccacgggagtagttaa
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