Neogale vison (American mink): 122889248
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Entry
122889248 CDS
T08764
Symbol
PDE4D
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00230
Purine metabolism
nvs01100
Metabolic pathways
nvs04024
cAMP signaling pathway
nvs04928
Parathyroid hormone synthesis, secretion and action
nvs05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122889248 (PDE4D)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122889248 (PDE4D)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
122889248 (PDE4D)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122889248 (PDE4D)
Enzymes [BR:
nvs01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122889248 (PDE4D)
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GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
122889248
NCBI-ProteinID:
XP_044080173
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Position
1:227043295..228344189
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AA seq
809 aa
AA seq
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MEAEGSSVPARAGSDEGSDGAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPSSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRA
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEETVGEEEDSQPEPCGIEDHSPDT
NT seq
2430 nt
NT seq
+upstream
nt +downstream
nt
atggaggcagagggcagcagcgtgccggcccgtgcgggcagcgacgagggcagcgacggc
gccggaggggccacactcaaagcccccaagcacctctggaggcacgagcagcaccaccag
tacccgctccggcagccccagttccgccttctgcacccccatcaccacctgcccccgcca
ccgccgtcctcaccccagccccagccccagtgtccgctgcagccgccaccgccaccccct
ctgccaccgcccccgccgcctccgggggctgctcgcggccgctacgcctcgagcggggcc
accggccgggtccgacatcgcggctactcggacaccgagcgctacctgtactgccgtgcc
atggaccgcacctcctacgccgtggagaccggccaccggcccggcctaaagaaatccagg
atgtcctggccctcctccttccagggactcaggcgttttgatgtggacaatggcacatct
gcgggacggagtcccttggatcccatgaccagcccaggatccgggctaattctccaagca
aactttgtccacagtcagcgtcgcgagtcttttctgtatcgatctgacagcgattatgac
ctgtctccaaagtctatgtcccggaactcctccattgccagtgatatacatggagatgac
ttgattgtgactccatttgctcaggtcttggccagcctgcgaactgtacgaaacaacttt
gctgcattaactaatttgcaagatcgagcacctagcaaaagatcacccatgtgcaaccag
ccatccatcaacaaagccaccataacagaggaggcctaccagaaactggccagcgagacc
ctggaggagctggactggtgtctggaccagctagagaccctgcagaccaggcactccgtc
agtgagatggcctccaacaagtttaaaaggatgcttaatcgggagctcacccatctctct
gaaatgagtcggtctggaaatcaagtgtcagagtatatatcaaacacattcttagataag
caacatgaagtggaaattccttctccaactcagaaggaaaaggagaaaaagaaaaggcca
atgtctcagatcagtggggtcaagaagttgatgcacagctccagtttgacgaattcaagc
atcccgagatttggggttaaaactgaacaagaggatgtccttgccaaggaactagaagat
gtgaacaaatggggtcttcatgttttcagaatagcagagctgtccggtaaccggcctttg
actgttatcatgcatactatttttcaggaacgggatttattaaaaacatttaaaattcca
gtagacactttaattacataccttatgactctggaagaccattaccacgctgacgtggcc
taccacaataatattcatgctgcagatgttgtccagtcgacacatgtgctattatctaca
cctgctttggaggctgtgtttacagatttggagattcttgcagcaatttttgccagtgca
atacatgatgtagatcatcccggtgtgtcaaatcagtttctcatcaatacaaactctgaa
cttgccttgatgtacaatgattcttctgtcttggagaaccaccatttggctgtgggcttt
aagttgcttcaggaagaaaactgtgatattttccagaatttgaccaaaaagcaaagacaa
tcattaaggaagatggtcattgacattgtacttgcaacagacatgtcaaaacacatgaat
ctactggctgatttgaaaactatggttgaaactaagaaagtgacaagttctggagttctt
cttcttgataactattctgataggattcaggtccttcagaatatggtgcactgtgcagac
ctgagcaaccccacgaagccgctccagctgtaccgccagtggacagaccgcatcatggag
gagttcttccgccaaggagacagagagagggagcgaggcatggagatcagtcccatgtgt
gacaagcacaatgcatccgtggaaaagtcacaggtgggcttcatagactatattgttcat
cctctctgggagacatgggccgacctcgtgcatcctgatgcccaggacattctggacact
ttggaggacaatcgtgaatggtaccagagcacaattcctcagagcccctccccagcacct
gatgaccaggaggaaggccggcagggtcaaaccgagaagttccagtttgaactaacttta
gaagaagatggcgagtctgacaccgaaaaggacagtggaagtcaggtggaagaagacact
agctgcagtgactccaagactctctgtactcaagactcggagtctactgaaattcccctt
gatgagcaggtggaagaggaaacagtgggggaggaagaagacagccagcctgaaccctgt
ggaatagaagatcattctcctgacacgtaa
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