Neogale vison (American mink): 122890476
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Entry
122890476 CDS
T08764
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00010
Glycolysis / Gluconeogenesis
nvs00020
Citrate cycle (TCA cycle)
nvs00620
Pyruvate metabolism
nvs00785
Lipoic acid metabolism
nvs01100
Metabolic pathways
nvs01200
Carbon metabolism
nvs01210
2-Oxocarboxylic acid metabolism
nvs04066
HIF-1 signaling pathway
nvs04922
Glucagon signaling pathway
nvs05230
Central carbon metabolism in cancer
nvs05415
Diabetic cardiomyopathy
Module
nvs_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122890476 (PDHA2)
00020 Citrate cycle (TCA cycle)
122890476 (PDHA2)
00620 Pyruvate metabolism
122890476 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122890476 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122890476 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122890476 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122890476 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122890476 (PDHA2)
Enzymes [BR:
nvs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
122890476 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
122890476
NCBI-ProteinID:
XP_044082054
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All DBs
Position
11:complement(111744257..111745432)
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AA seq
391 aa
AA seq
DB search
MKKMLTAAVSRVWSGVAQKPASRVLVASCNLSKDATFEIKKCDLYRLEEGPPDTTVLTRE
DGLKYYRMMQTIRRMELRADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGIAL
ACKYKGENEVCLTLYGDGAANQGQIAEAYNMAALWKLPCVFICENNLYGMGTSAERAAAS
TDYYKRGNFIPGLRVDGMDVLCVREATRFAADYCRSEKGPIVMELLTYRYHGHSMSDPGV
SYRTRQEIQSVRSKSDPIMLLKNRMVDSKLATIEEFKEIDVEVRKEIDDAVHFATTDPEP
ALEELGHHIYCDNPPFEVRGTSQWIKFKSLP
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcaccgccgcggtctcccgcgtgtggtctggggtcgcccagaagccc
gctagcagagtgctcgtggcatcctgtaacctttcaaaagatgctacatttgaaattaag
aaatgtgacctttatcgattagaagagggtccccctgacacaacagtgctcacccgggag
gatgggcttaaatactacaggatgatgcagactattcgcagaatggaattgagggccgat
cagctgtataaacaaaagttcattcgtgggttctgtcacttatgcgatggtcaggaagct
tgttgcgtgggcctggaggctgggataaatcccacggatcatgtcatcacatcctacagg
gctcatggcttgtgctatactcgtgggctttctgtccgatcaattctcgcagagctgaca
ggacggaagggaggctgtgctaaaggaaagggagggtctatgcatatgtatgcaaagaac
ttctatgggggcaacggcattgttggcgcccagggacccctaggagctggtatcgccctg
gcctgtaaatataagggcgaaaatgaggtctgtttgacactctatggggatggtgctgcg
aatcagggccagatagctgaagcttacaatatggccgctttgtggaaattaccttgtgtt
ttcatctgtgagaataacctttatggaatgggcacctctgccgagagagcagcagccagc
actgattactacaagagaggaaattttatccctggactaagggtggatggaatggatgtt
ctatgtgttcgggaggcaactaggtttgcagctgactactgcagatctgaaaaggggccc
atagtgatggagctgctgacataccgttatcatggacacagcatgagtgaccctggagtg
agttatcgtacacgacaagaaattcagagcgtaagaagtaaaagtgatcctattatgctc
ctcaaaaatagaatggtagacagtaagcttgccaccattgaagaattcaaggaaattgat
gtggaagtgaggaaagaaattgacgatgcagtccactttgctacaactgatcctgaacca
gctttggaggaattaggtcatcacatttactgcgataatccgccttttgaagttcgtggt
acaagtcagtggatcaagtttaagtctctcccttaa
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