KEGG   Neogale vison (American mink): 122891909
Entry
122891909         CDS       T08764                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
nvs  Neogale vison (American mink)
Pathway
nvs01522  Endocrine resistance
nvs04010  MAPK signaling pathway
nvs04015  Rap1 signaling pathway
nvs04068  FoxO signaling pathway
nvs04071  Sphingolipid signaling pathway
nvs04114  Oocyte meiosis
nvs04148  Efferocytosis
nvs04218  Cellular senescence
nvs04261  Adrenergic signaling in cardiomyocytes
nvs04370  VEGF signaling pathway
nvs04380  Osteoclast differentiation
nvs04550  Signaling pathways regulating pluripotency of stem cells
nvs04611  Platelet activation
nvs04613  Neutrophil extracellular trap formation
nvs04620  Toll-like receptor signaling pathway
nvs04621  NOD-like receptor signaling pathway
nvs04622  RIG-I-like receptor signaling pathway
nvs04625  C-type lectin receptor signaling pathway
nvs04657  IL-17 signaling pathway
nvs04658  Th1 and Th2 cell differentiation
nvs04659  Th17 cell differentiation
nvs04660  T cell receptor signaling pathway
nvs04664  Fc epsilon RI signaling pathway
nvs04668  TNF signaling pathway
nvs04670  Leukocyte transendothelial migration
nvs04714  Thermogenesis
nvs04722  Neurotrophin signaling pathway
nvs04723  Retrograde endocannabinoid signaling
nvs04728  Dopaminergic synapse
nvs04750  Inflammatory mediator regulation of TRP channels
nvs04912  GnRH signaling pathway
nvs04914  Progesterone-mediated oocyte maturation
nvs04917  Prolactin signaling pathway
nvs04926  Relaxin signaling pathway
nvs04932  Non-alcoholic fatty liver disease
nvs04933  AGE-RAGE signaling pathway in diabetic complications
nvs04935  Growth hormone synthesis, secretion and action
nvs04936  Alcoholic liver disease
nvs05014  Amyotrophic lateral sclerosis
nvs05020  Prion disease
nvs05022  Pathways of neurodegeneration - multiple diseases
nvs05132  Salmonella infection
nvs05133  Pertussis
nvs05135  Yersinia infection
nvs05140  Leishmaniasis
nvs05142  Chagas disease
nvs05145  Toxoplasmosis
nvs05152  Tuberculosis
nvs05161  Hepatitis B
nvs05163  Human cytomegalovirus infection
nvs05167  Kaposi sarcoma-associated herpesvirus infection
nvs05169  Epstein-Barr virus infection
nvs05170  Human immunodeficiency virus 1 infection
nvs05171  Coronavirus disease - COVID-19
nvs05205  Proteoglycans in cancer
nvs05208  Chemical carcinogenesis - reactive oxygen species
nvs05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nvs05415  Diabetic cardiomyopathy
nvs05417  Lipid and atherosclerosis
nvs05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nvs00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122891909 (MAPK12)
   04015 Rap1 signaling pathway
    122891909 (MAPK12)
   04370 VEGF signaling pathway
    122891909 (MAPK12)
   04668 TNF signaling pathway
    122891909 (MAPK12)
   04068 FoxO signaling pathway
    122891909 (MAPK12)
   04071 Sphingolipid signaling pathway
    122891909 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    122891909 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    122891909 (MAPK12)
   04218 Cellular senescence
    122891909 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    122891909 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122891909 (MAPK12)
   04613 Neutrophil extracellular trap formation
    122891909 (MAPK12)
   04620 Toll-like receptor signaling pathway
    122891909 (MAPK12)
   04621 NOD-like receptor signaling pathway
    122891909 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    122891909 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    122891909 (MAPK12)
   04660 T cell receptor signaling pathway
    122891909 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    122891909 (MAPK12)
   04659 Th17 cell differentiation
    122891909 (MAPK12)
   04657 IL-17 signaling pathway
    122891909 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    122891909 (MAPK12)
   04670 Leukocyte transendothelial migration
    122891909 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122891909 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    122891909 (MAPK12)
   04917 Prolactin signaling pathway
    122891909 (MAPK12)
   04926 Relaxin signaling pathway
    122891909 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    122891909 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122891909 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    122891909 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    122891909 (MAPK12)
   04722 Neurotrophin signaling pathway
    122891909 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122891909 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122891909 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    122891909 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122891909 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    122891909 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122891909 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122891909 (MAPK12)
   05161 Hepatitis B
    122891909 (MAPK12)
   05171 Coronavirus disease - COVID-19
    122891909 (MAPK12)
   05163 Human cytomegalovirus infection
    122891909 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122891909 (MAPK12)
   05169 Epstein-Barr virus infection
    122891909 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122891909 (MAPK12)
   05135 Yersinia infection
    122891909 (MAPK12)
   05133 Pertussis
    122891909 (MAPK12)
   05152 Tuberculosis
    122891909 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122891909 (MAPK12)
   05140 Leishmaniasis
    122891909 (MAPK12)
   05142 Chagas disease
    122891909 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    122891909 (MAPK12)
   05020 Prion disease
    122891909 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    122891909 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122891909 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    122891909 (MAPK12)
   05415 Diabetic cardiomyopathy
    122891909 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    122891909 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    122891909 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122891909 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122891909 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nvs01001]
    122891909 (MAPK12)
Enzymes [BR:nvs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     122891909 (MAPK12)
Protein kinases [BR:nvs01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   122891909 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 122891909
NCBI-ProteinID: XP_044083888
LinkDB
Position
12:514739..523525
AA seq 287 aa
MRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLSEDRIQFLVYQMLKG
LKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNW
TRYTQTVDIWSAGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSADAKN
YMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAERRVTAAEALTHPYFESLQDTEDE
PAARKYDESFADTDHTLDEWKRVTYKEVLSFKPPRQLGTKVSKETAL
NT seq 864 nt   +upstreamnt  +downstreamnt
atgcgccacgagaacgtcatcgggctgctggatgtgttcactcctgatgaaaccctggat
gatttcacagacttttacctggtgatgccgttcatggggactgacctgggcaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttcctcgtctaccagatgctgaagggg
ctaaagtatatccatgctgctggcatcatccacagggacctgaagcccggcaatctggct
gtgaacgaggactgtgagctgaagatcctggactttggcctggcgaggcaggccgacagc
gagatgaccgggtatgtggtgacccggtggtaccgggcacccgaggtcatcttgaattgg
acgcgctacacgcagacagtggacatctggtcggcgggctgcatcatggcagagatgatc
acagggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatcatgaag
gtgaccgggacgcctcctgccgagtttgttcagaggctgcagagtgccgatgcgaagaac
tacatgaagggcctccccgagttggagaagaaggattttgcctccatcctgacgaatgca
agccctctggccgtgaaccttctggagaagatgctggtactggatgcagagcggcgggtg
accgcggccgaggcgctgacccacccctacttcgagtcactacaggacacggaggacgag
cccgcggcccggaagtacgacgagtcctttgctgatacggatcacacgctggacgagtgg
aagcgtgtcacatataaagaagtgctcagcttcaagcctccccggcagttggggaccaag
gtctccaaggagacggctctgtga

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