Neogale vison (American mink): 122896073 Help Entry 122896073         CDS       T08764                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism nvs  Neogale vison (American mink) Pathway nvs00230   Purine metabolism nvs01100   Metabolic pathways nvs01522   Endocrine resistance nvs04015   Rap1 signaling pathway nvs04020   Calcium signaling pathway nvs04022   cGMP-PKG signaling pathway nvs04024   cAMP signaling pathway nvs04062   Chemokine signaling pathway nvs04072   Phospholipase D signaling pathway nvs04114   Oocyte meiosis nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04261   Adrenergic signaling in cardiomyocytes nvs04270   Vascular smooth muscle contraction nvs04371   Apelin signaling pathway nvs04540   Gap junction nvs04611   Platelet activation nvs04713   Circadian entrainment nvs04714   Thermogenesis nvs04723   Retrograde endocannabinoid signaling nvs04724   Glutamatergic synapse nvs04725   Cholinergic synapse nvs04727   GABAergic synapse nvs04750   Inflammatory mediator regulation of TRP channels nvs04911   Insulin secretion nvs04912   GnRH signaling pathway nvs04913   Ovarian steroidogenesis nvs04914   Progesterone-mediated oocyte maturation nvs04915   Estrogen signaling pathway nvs04916   Melanogenesis nvs04918   Thyroid hormone synthesis nvs04921   Oxytocin signaling pathway nvs04922   Glucagon signaling pathway nvs04923   Regulation of lipolysis in adipocytes nvs04925   Aldosterone synthesis and secretion nvs04926   Relaxin signaling pathway nvs04927   Cortisol synthesis and secretion nvs04928   Parathyroid hormone synthesis, secretion and action nvs04934   Cushing syndrome nvs04935   Growth hormone synthesis, secretion and action nvs04970   Salivary secretion nvs04971   Gastric acid secretion nvs04972   Pancreatic secretion nvs04976   Bile secretion nvs05032   Morphine addiction nvs05163   Human cytomegalovirus infection nvs05166   Human T-cell leukemia virus 1 infection nvs05200   Pathways in cancer nvs05207   Chemical carcinogenesis - receptor activation nvs05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:nvs00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122896073 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122896073 (ADCY2)    04371 Apelin signaling pathway     122896073 (ADCY2)    04020 Calcium signaling pathway     122896073 (ADCY2)    04072 Phospholipase D signaling pathway     122896073 (ADCY2)    04024 cAMP signaling pathway     122896073 (ADCY2)    04022 cGMP-PKG signaling pathway     122896073 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122896073 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     122896073 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122896073 (ADCY2)    04062 Chemokine signaling pathway     122896073 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     122896073 (ADCY2)    04922 Glucagon signaling pathway     122896073 (ADCY2)    04923 Regulation of lipolysis in adipocytes     122896073 (ADCY2)    04912 GnRH signaling pathway     122896073 (ADCY2)    04913 Ovarian steroidogenesis     122896073 (ADCY2)    04915 Estrogen signaling pathway     122896073 (ADCY2)    04914 Progesterone-mediated oocyte maturation     122896073 (ADCY2)    04921 Oxytocin signaling pathway     122896073 (ADCY2)    04926 Relaxin signaling pathway     122896073 (ADCY2)    04935 Growth hormone synthesis, secretion and action     122896073 (ADCY2)    04918 Thyroid hormone synthesis     122896073 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     122896073 (ADCY2)    04916 Melanogenesis     122896073 (ADCY2)    04925 Aldosterone synthesis and secretion     122896073 (ADCY2)    04927 Cortisol synthesis and secretion     122896073 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122896073 (ADCY2)    04270 Vascular smooth muscle contraction     122896073 (ADCY2)   09154 Digestive system    04970 Salivary secretion     122896073 (ADCY2)    04971 Gastric acid secretion     122896073 (ADCY2)    04972 Pancreatic secretion     122896073 (ADCY2)    04976 Bile secretion     122896073 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     122896073 (ADCY2)    04727 GABAergic synapse     122896073 (ADCY2)    04725 Cholinergic synapse     122896073 (ADCY2)    04723 Retrograde endocannabinoid signaling     122896073 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     122896073 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     122896073 (ADCY2)    04213 Longevity regulating pathway - multiple species     122896073 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     122896073 (ADCY2)    04714 Thermogenesis     122896073 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122896073 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     122896073 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122896073 (ADCY2)    05163 Human cytomegalovirus infection     122896073 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     122896073 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122896073 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122896073 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122896073 (ADCY2) Enzymes [BR:nvs01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122896073 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  122896073 NCBI-ProteinID:  XP_044089951 LinkDB All DBs Position 1:complement(311236659..311642750) Genome browser AA seq 1093 aa AA seqDB search MWREAMRRRRYLRDRAEAAAAAAGGGDGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMGA CLALLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWLCL VAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCL SATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEK RQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIV GFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKN CVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHME AGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPHLFR PRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNR TLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATALP AFKYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLVLAFTLFICFAGQLLQCSKKA SASLLWLLKSSGIIADRPWPRVSLTVLTTAIILTMAVFNMFFLSDPEETIPPTANTSNAS LSALSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVAYNTILL HTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFVTLLVLGRQSEYYCRLDFLWKNKF KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFKE FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE HTQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY DIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGELKTYFVNT EMSRSLSQSNLAS NT seq 3282 nt NT seq  +upstreamnt  +downstreamnt atgtggcgggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggcggcggcg gcggcggcgggcggcggcgacgggctgcagcggtcccgggactggctctacgagtcctac tactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcc tgcctcgccctgctcgccgtcttcttcgcgctccggctggaagtcgaagaccacgtggca tttttaataacggtcccgacagccctggcgattttcttcgcgatattcatccttgtgtgc atcgagtccgtgtttaagaagctgctccgtcttttttccttggtgatatggctgtgtctc gtggccatggggtacctgttcatgtgctttggaggcaccgtctctccctgggaccaggtg tcattcttcctcttcatcatcttcgtggtgtacaccatgctccccttcaacatgcgagat gccatcatcgctagcgtgctcacctcttcctcccacaccatcgtgctgagcgtctgcctc tctgcgaccccgggggccaaggagcacctggtctggcagatcctggccaacgtgatcatt ttcatctgtgggaacctggcgggcgcgtaccacaagcatctcatggagctcgccctgcag cagacctaccaggacacgtgcaactgtatcaagtctcgaatcaagctggaatttgaaaag cggcagcaggagcggctcctgctctctctgctgccagcgcacatagccatggagatgaaa gccgagatcatccagaggctgcagggccccaaggccggccaaatggaaaacacaaacaac ttccacaacctgtatgtcaagcggcacaccaacgtgagcatcctgtacgctgacatcgtg ggcttcacccggctggccagtgactgctctccgggagaactcgtccacatgctgaatgag ctctttggaaagtttgaccaaattgcaaaggagaatgaatgcatgagaataaagattttg ggagactgctactactgtgtgtccggactccccatatctctcccgaaccacgccaagaac tgtgtgaaaatggggctggacatgtgtgaagctataaagaaagtgagggacgccaccgga gtggatatcaacatgcgcgtgggagtgcattctggcaatgtcctctgcggggtgattggt ctgcagaagtggcagtatgatgtgtggtcacatgatgttaccttggccaatcacatggaa gccggaggggttcctggacgtgttcacatttcttccgtcactctggagcacttgaacggc gcttataaagtggaggaaggagacggtgacatccgagacccgtatttaaaacagcacctg gtgaaaacctactttgtaatcaaccccaagggagagcgaaggagtcctcacctcttcaga cctcgccacactctcgatggagccaagatgagggcctccgtgcgcatgacccggtacctg gagtcctggggagcagccaagcccttcgcacacctgcaccaccgagacagcatgaccaca gagaacggcaagatcagcaccacggatgtaccaatgggccagcataattttcagaatcgc accttgagaaccaagtcccaaaagaagagatttgaagaagaattaaatgaaaggatgatt caagcaattgatggaattaatgcccaaaagcagtggctgaagtctgaagacattcagagg atctcactcctattctacaataaaatactagagaaagaataccgagccaccgccctgcca gcgtttaagtactacgtgacctgcgcgtgtctcattttcttctgcatcttcattgtgcag atcctagtattaccgaaaacgtccgtcctggggatctcctttggagctgcatttctcgtg ctcgccttcaccctcttcatctgctttgcaggacagcttttgcaatgcagcaagaaagcc tcggcctctctcctgtggctgctgaagtcgtcgggcatcatcgcggaccggccctggccg cgcgtctccctcaccgtcctcaccacggccatcattctgaccatggccgtgttcaacatg tttttcctgagtgacccagaggaaacaattcctccaactgccaatacatccaacgccagt ctttccgccttaagtaatcaggcagcgatcctgcgggcacaaaatctgtttttcctcccg tacttcatctacagctgcatcctgggactgatttcctgctcagtcttcctgagggtcaac tacgagctgaagatgttgatcatgatggtggctttggtggcctacaacaccatcctgctg cacactcacgcccacgtcctggacgactacagccaggtcttattcgagagaccaggcatt tggaaagacctgaagaccatgggctcagtgtctctctttatattcttcgtcacactgctc gttctgggtagacagagtgaatattactgtaggttagacttcttgtggaagaacaagttc aaaaaagagcgggaggagatagaaaccatggagaacctgaaccgcgtgctgctggagaac gtgctgcccgcgcacgtggcggagcatttcctggcccggagcctgaagaacgaggactta taccaccagtcctatgactgtgtctgcgtcatgtttgcctctattccggatttcaaagaa ttctacacggaatcagatgtgaacaaggagggcttggaatgccttcggctcctgaatgag atcatcgctgactttgatgatctgctctccaagccgaaattcagtggcgttgaaaagatc aagaccattggcagcacatacatggcagcgacgggtctgagcgccgtgcctagccaggag cacacccaggagcccgagcggcagtacatgcacatcggcaccatggtggagttcgccttc gcgctggtggccaagctggacgccatcaacaagcactccttcaacgacttcaagctgcgc gtcggtattaaccacggacctgtgatagcgggtgtcattggagctcagaagccgcagtat gatatctggggcaacaccgtaaatgtggccagcaggatggacagcactggtgtattggac aaaatacaggtcaccgaggagacaagcctcgtcctccagaccctgggctacacgtgcacc tgcagaggaataatcaacgtgaaaggcaagggggagctgaagacgtactttgtaaacaca gaaatgtcacggtccctttcccagagcaacctggcgtcctga

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