Neogale vison (American mink): 122897651
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Entry
122897651 CDS
T08764
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00010
Glycolysis / Gluconeogenesis
nvs00020
Citrate cycle (TCA cycle)
nvs00620
Pyruvate metabolism
nvs00785
Lipoic acid metabolism
nvs01100
Metabolic pathways
nvs01200
Carbon metabolism
nvs01210
2-Oxocarboxylic acid metabolism
nvs04066
HIF-1 signaling pathway
nvs04922
Glucagon signaling pathway
nvs05230
Central carbon metabolism in cancer
nvs05415
Diabetic cardiomyopathy
Module
nvs_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122897651 (PDHA1)
00020 Citrate cycle (TCA cycle)
122897651 (PDHA1)
00620 Pyruvate metabolism
122897651 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122897651 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122897651 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122897651 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122897651 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122897651 (PDHA1)
Enzymes [BR:
nvs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
122897651 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
MIF4G_like
Motif
Other DBs
NCBI-GeneID:
122897651
NCBI-ProteinID:
XP_044091943
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All DBs
Position
X:complement(116526541..116541848)
Genome browser
AA seq
389 aa
AA seq
DB search
MRKMLAAVSRVLGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDG
LKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAH
GFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALAC
KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTD
YYKRGDFIPGLRVDGMDVLCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSY
RTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPL
EELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctctcgcgtgttgggcgtcgcccagaagccggcaagc
agagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaatgc
gatcttcaccggctggaggagggccctcctgtcaccacagtgctcaccagggaggacggg
ctcaagtactacaggatgatgcagacggtccgccggatggagttaaaggcagatcagctg
tacaagcagaagattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgttgt
gtgggcttggaggctggcataaatcccacagaccatcttatcacagcgtatcgggctcat
ggctttaccttcactcgtgggctttctgtccgagaaattctcgcagagcttacagggcga
agaggaggctgtgctaaagggaaaggtggatcgatgcacatgtacgccaagaacttctac
gggggcaacggcatcgtcggagctcaggtgcccttgggagcggggattgctttggcctgt
aagtataacggaaaggatgaggtctgtctgactttatatggcgacggtgctgctaatcag
ggtcagatatttgaagcttacaacatggcagctttgtggaaactgccgtgtattttcatc
tgtgagaacaaccgctatggaatgggaacatctgttgagagagcagcggccagcacggac
tactacaagagaggcgacttcatccctgggctgagggtagatggaatggacgtcttgtgt
gtccgggaggcaacaaggtttgcagctgcctactgtagatctggaaaggggcccatactg
atggagctacagacctaccgttaccacggacacagcatgagcgaccctggcgtcagttac
cgtacccgagaagagattcaggaagtaagaagtaagagtgaccctatcatgctgctcaag
gataggatggtgaacagcaatctggccagcgttgaagaattaaaggaaattgatgttgaa
gtgaggaaggaaattgaggatgctgcccagtttgccactgcggatcccgaaccgcctttg
gaagagctgggctaccacatttacagcagcgacccgccttttgaagttcggggtgccaat
cagtggatcaagtttaagtccatcagttaa
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