Neogale vison (American mink): 122906270
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Entry
122906270 CDS
T08764
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs01524
Platinum drug resistance
nvs04010
MAPK signaling pathway
nvs04071
Sphingolipid signaling pathway
nvs04141
Protein processing in endoplasmic reticulum
nvs04210
Apoptosis
nvs04530
Tight junction
nvs04668
TNF signaling pathway
nvs04714
Thermogenesis
nvs04722
Neurotrophin signaling pathway
nvs04932
Non-alcoholic fatty liver disease
nvs04936
Alcoholic liver disease
nvs05010
Alzheimer disease
nvs05012
Parkinson disease
nvs05014
Amyotrophic lateral sclerosis
nvs05016
Huntington disease
nvs05017
Spinocerebellar ataxia
nvs05022
Pathways of neurodegeneration - multiple diseases
nvs05208
Chemical carcinogenesis - reactive oxygen species
nvs05417
Lipid and atherosclerosis
nvs05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
122906270 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122906270 (MAP3K5)
04668 TNF signaling pathway
122906270 (MAP3K5)
04071 Sphingolipid signaling pathway
122906270 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
122906270 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
122906270 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
122906270 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
122906270 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
122906270 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
122906270 (MAP3K5)
05012 Parkinson disease
122906270 (MAP3K5)
05014 Amyotrophic lateral sclerosis
122906270 (MAP3K5)
05016 Huntington disease
122906270 (MAP3K5)
05017 Spinocerebellar ataxia
122906270 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
122906270 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122906270 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
122906270 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122906270 (MAP3K5)
04932 Non-alcoholic fatty liver disease
122906270 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
122906270 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nvs01001
]
122906270 (MAP3K5)
Enzymes [BR:
nvs01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
122906270 (MAP3K5)
Protein kinases [BR:
nvs01001
]
Serine/threonine kinases: STE group
STE11 family
122906270 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
122906270
NCBI-ProteinID:
XP_044103954
LinkDB
All DBs
Position
1:64929854..65166033
Genome browser
AA seq
1395 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSCRRGGAAVAAEDEESQLPPPGSLWNVETAAAPGTGCPAA
TSGSSATRCRGNSSSGGGRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLETL
HFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNNSD
SLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPIC
LPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLT
ADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAK
ALDVMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDHGASWFKKAFESEPSLQ
SGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLAND
HMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEAT
KTNVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSAASIR
GVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCEGDS
LEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHK
HLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEG
LKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEI
IDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAE
AKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVP
VLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSA
PPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHITTL
IASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPH
WMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLEAEDDHEERPSNQTIRRP
HAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVRKEKELQALL
HQAIEEKDQEIKHLKLKSQPIDIPGLPACPRDSPGTNTEESELTEWLRDKGADEDTISRF
LAEDYSLEDVLYYVTRDDLKCLRLRYHSFLYVPFSWWKERWAEKSGILSCLAGPLPSPYH
LSGPGAHSVVHICSA
NT seq
4188 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaagcgggcgagggcatcactttctcggtgccacccttcgccgagggtgga
agctgccggaggggaggagcggcggtggcagccgaggacgaggagagccagctaccgccg
ccgggcagcttatggaacgtagagactgccgccgcccctggcaccggttgtcctgccgcc
acctctgggagcagcgccacccgatgccggggcaactctagtagcggaggcggccgacgg
accacggtggcatatgttatcaacgaagcgagccaggggcagctggtggtggccgagagc
gaggccctgcagagcctgcgggaggcgtgtgagacggtgggcgccaccctggagaccctg
cattttggtaaactggactttggagaaaccaccgtgctggaccgtttttacaatgcagat
attgcggtggtggagatgagtgatgccttccgacagccgtccttgttttaccaccttgga
gtgagagaaagcttcagcatggccaacaacatcatcctctactgtgataacaactcagac
tctctgcagtccctgaaggaaatcatttgccagaagaacaccatgtgcactgggaactat
acattcgtcccttacatgatcactccacacaacaaggtctactgctgtgatagcagcttc
atgaaggggttgacggagctcatgcaaccgaacttcgagctgcttcttggacccatttgc
ttacctcttgtggatcgtttcattcagcttctgaaggtggcacaagcaagttctagccag
tatttccgggaatctattctcaatgatatcaggaaagctcgaaatttatacactggtaaa
gaattggcagctgaattggcaagaattcggcaacgagtagataatatcgaagtcttaaca
gcagatattgtcataaacctcttactttcctacagagatatccaggactatgattctata
gtgaagctggtagagaccttagaaaagctgccaacctttgatttggcttcccatcaccac
gtgaagtttcattatgcatttgcactgaataggagaaatctccctggagatagagccaaa
gctcttgatgttatgatcccgctggtgcaaagtgaagggcaggttgcctccgatatgtat
tgcctagttggtcgaatctacaaagatatgtttttggactctaatttcctggacactgaa
agtagagaccatggagcttcttggttcaaaaaggcgtttgaatctgagccatcgctacag
tcgggaattaattatgcggtccttctcctggcagctgggcatcagtttgaatcttccttt
gagctccggaaagttggggtgaagctgagtagcctccttggcaaaaaaggaaacttagaa
aaacttcagagctactgggaagttggattttttctgggtgccagtgtcctggccaatgac
cacatgagagtcatccaagcatctgaaaagctttttaaactgaagaccccagcatggtac
ctcaagtcgattgtagagacaattttgatatataagcattttgtgaaactaactacagag
cagcctgtggccaagcaggagctcgtggacttctggatggacttcttggtcgaggccaca
aagaccaatgttactgttgttaggtttccagtactaatattggaaccaaccaaaatctat
caaccttcatatttgtctatcaacaatgaagttgaggaaaagacaatatctatttggcat
gtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgctgcttctatcagg
ggagtgagtatttctaaatttgaagagcgatgctgttttctttacgtgcttcataattct
gacgatttccaaatctatttctgtacagaactgcattgtaaaaagttttttgaaatggtg
aacaccatcactgaggagaaggggagaagcacagaggaaggtgattgtgaaggtgactcc
ttggagtatgactacgaatatgacgagaatggtgacagagttgttttagggaaaggcact
tacgggatcgtctacgcaggccgagacctgagcaaccaagtcagaatcgctataaaggaa
attccagagagagacagcagatactcccagcccctgcatgaagaaatagcattgcataag
catctgaagcacaaaaatattgtccagtatctgggctctttcagtgagaatggctttatc
aaaatcttcatggagcaggtcccaggaggaagtctgtctgctctccttcgttccaaatgg
ggcccattgaaggacaatgagcaaacaatcggcttttatacaaagcagatacttgaagga
ttaaaatacctccatgacaatcagatagtccaccgggatataaagggcgacaatgtgttg
attaatacttatagtggtgttctcaagatctcggacttcgggacatcaaagaggctagct
ggcataaatccatgtaccgaaacttttactggtacccttcagtatatggcaccggaaatc
atagacaaaggaccacgaggctatgggaaagcagcagacatctggtctttgggctgcacc
atcatcgaaatggccacagggaaaccacctttttatgagctgggagaaccacaagcagct
atgttcaaggtgggaatgtttaaagtccacccagagatcccagagtccatgtcagcagag
gccaaggcattcatactgaagtgttttgaacctgaccctgacaagagagcctgtgctaac
gacttgcttgttgatgagttcttaaaagtttcgagcaaaaagaaaaagacacaacctaag
ctttcagccctttcagctggatcaaatgagtatcttcgaagcatatccttacctgtgcct
gtcctggtggaggacacgagcagcagcagcgagtacggctcagtttctcctgacacagag
ttaaaggtggaccccttctctttcaaaacgagagccaaatcctgcggagaaagagatgta
aaaggaatacggacgctctttttgggcattccggatgaaaattttgaagatcacagtgct
cccccttcccctgaagaaaaagattctggtttcttcatgttgaggaaggacagtgagaga
cgcgccacccttcataggatcctgacggaagaccaagacaaagttgtgagaaacttaatg
gaatcattggctcagggggctgaagaacctaaactaaaatgggaacatatcacaaccctc
atcgcaagcctcagagaatttgtgagatccacagaccgaaaaatcatcgccaccacactg
tccaagctgaagctggaacttgacttcgacagccacggcattagccaggttcaggtggtg
ctcttcggttttcaagatgctgtcaataaagttcttcggaatcataatatcaagccacac
tggatgtttgccttagacagtatcatccgaaaggcggtgcagacggccatcaccattctg
gtgccagaactgaggccacacttcagcctcgcatctgagagcgataccgctgatcaagaa
gacttggaggcagaagatgaccatgaggaacggccttcgaaccaaactatccgaagacct
catgctgtcattgaagatgctgtagctacctcaggggtgagcacactcagttctactgta
tcccacgactcccaaaatgcccaccggtccctcaatgtgcaacttggaaggatgaaaata
gaaactaatagattactggaagaattggttcggaaagaaaaagaattacaagcactcctt
catcaagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcccaacca
atagatattcctggattgcctgcatgcccccgggattctcctggcacaaatactgaagag
tctgagcttactgagtggctgagagataagggagctgatgaagacactataagtcggttt
ttggctgaggattattcactagaggatgttctctactatgttacacgtgatgatttaaaa
tgcctcagactaaggtaccactcttttctttatgtccctttttcttggtggaaagagcgc
tgggctgagaagtctgggatcctgtcctgcctggctggacccctccccagcccttaccat
ctcagcggtcctggggctcattctgtggttcacatttgctctgcgtaa
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