Ornithorhynchus anatinus (platypus): 100088094
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Entry
100088094 CDS
T01045
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00280
Valine, leucine and isoleucine degradation
oaa00640
Propanoate metabolism
oaa00785
Lipoic acid metabolism
oaa01100
Metabolic pathways
oaa01210
2-Oxocarboxylic acid metabolism
Module
oaa_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100088094 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100088094 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100088094 (BCKDHA)
Enzymes [BR:
oaa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
100088094 (BCKDHA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100088094
NCBI-ProteinID:
XP_028922192
Ensembl:
ENSOANG00000008790
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All DBs
Position
5:2369570..2379766
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AA seq
458 aa
AA seq
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MAAKMASGRLAWALRGGLRRGWRGLGARPGPRSPPPSSPPPGARGLTASAPRQQQEEFPS
LEEKPQFPGASAEFVDKLDFIQPNVISGIPVYRVMDRQGQIVNPEEDPQLPREQVLKFYR
SMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLVFGQYREAGVLMYR
GYPLDLFMSQCYGNASDPGKGRQMPVHYGCKDLHFVTISSPLATQIPQAVGAAYAAKREN
ANRAVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR
GPGYGIMSIRVDGNDVFAVYNATREARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRS
VDEVNYWDKQDHPISRLRHHLLSKGWWGEEEEKTWRKQSRKLVMEAFEAAERKLKPNLNL
LFSDVYREMPAHLQKQQDALARHLKTYGEHYPLDHFEQ
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atggcggccaagatggcgtcggggcgcctggcctgggcgctgaggggcggcctccgccgg
ggctggcgcggcctgggggcccggccggggcctcgctccccgccgccctcatcaccaccg
cccggggccaggggtctgaccgcctccgccccccggcagcagcaggaagaattcccatcg
ctggaagagaagccccagttcccgggggcctcggccgaattcgtggacaagctggacttt
atccagcccaacgtcatttccggcatccccgtctaccgggtcatggaccggcagggccag
atcgtgaaccccgaggaagacccccagctgccccgggaacaggtgctgaagttctacagg
agtatgacgctcctcaacaccatggaccgcatcctctatgagtctcagaggcagggccgc
atctccttctacatgaccaactacggcgaggagggcacccacgtcggtagcgccgccgcc
ctggacgacaccgacctggtgttcgggcagtaccgagaggcgggggtgctgatgtaccgc
ggctacccgctggacctcttcatgtcccagtgctacggtaacgccagtgacccgggcaaa
ggccgccagatgcccgtgcattacggctgcaaggacctgcacttcgtcaccatctcctcc
ccgctggctacccagatcccccaagcggtgggcgcggcctacgccgccaagagggagaac
gccaaccgggccgtcatctgctacttcggggagggggcggccagcgagggagacgcccac
gcgggcttcaacttcgccgccaccctggagtgccccatcatcttcttctgccgcaacaac
ggctacgccatctccacgccgacctcggagcagtaccgcggggacggcatcgccgccaga
ggccccggctacgggatcatgtcgatccgggtggacggcaacgacgtgtttgccgtctac
aacgccaccagggaagcccggcgccgggccgtggccgaaaaccagcccttcctcatcgag
gccatgacgtacaggatcgggcaccacagcacgagcgacgacagctcggcctaccgctcg
gtggacgaggtcaactactgggacaagcaggaccaccccatctcccgcctgcgccatcac
ctgctcagcaagggctggtggggggaggaagaggagaagacctggaggaagcagtcgcgc
aagctggtgatggaggccttcgaggcggcggaacggaagctgaagcccaacctcaacctg
ctgttctcggacgtgtaccgcgagatgcccgcccacctgcagaagcagcaggacgccctg
gcccgccacctcaagacctacggcgagcactaccccctggaccactttgagcagtga
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