KEGG   Ovis aries (sheep): 101102377
Entry
101102377         CDS       T03117                                 
Name
(RefSeq) cytochrome P450 11B1, mitochondrial isoform X4
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
oas  Ovis aries (sheep)
Pathway
oas00140  Steroid hormone biosynthesis
oas01100  Metabolic pathways
oas04927  Cortisol synthesis and secretion
oas04934  Cushing syndrome
Module
oas_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    101102377
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    101102377
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101102377
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:oas00199]
    101102377
Enzymes [BR:oas01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     101102377
Cytochrome P450 [BR:oas00199]
 Cytochrome P450, animal type
  CYP11 family
   101102377
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 101102377
NCBI-ProteinID: XP_027828617
EnsemblRapid: ENSOARG00020013707
LinkDB
Position
9:complement(14522651..14528804)
AA seq 454 aa
MALWAKVRLRMAGPWLSLHRARPLGTRATAAPKAVLPFEAMPRCPGNKWMWVLQIWKEQG
SENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQAESLHPQRMLLEPWLAYR
QARGHKCGVFLLNGPQWHLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNA
RGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMFKSTVQLMFV
PRRLSRWTSSSMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMT
LDTIKANTIDLTAGSVDTTAFSLLMTLFELARNPEVQQTLRQESLVAEAWISENPQRATT
ELPLLRAALKETLRLYPVGITLERQVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARP
ESYHPQRWLDRQGSGSRFPHLAFGFGVRQSACVL
NT seq 1365 nt   +upstreamnt  +downstreamnt
atggcgctgtgggcaaaggtcaggctgcggatggcaggaccctggctgtccctgcacagg
gcacgcccactgggcaccagagccactgcagcccccaaggcggtgctgcccttcgaagcc
atgccccggtgtcctggcaacaagtggatgtgggtgctgcagatctggaaggagcagggc
tctgagaacatgcacttggacatgcatcagaccttccaggagctggggcccattttcagg
tacgacgtgggagggagacacatggtgttcgtgatgctgcccgaggatgtggagaggctg
cagcaggcggagagccttcacccccagcggatgctcctggagccctggctggcctaccga
caggctcgcgggcacaagtgtggcgtgttcttgctcaacgggccccagtggcatttggac
cgactgcggctgaacccagacgtgctctcgctgccagccctgcagaagtacacgcccttg
gtggatggcgtggccagggacttctcccagaccctgaaggcaagggtgctgcagaatgct
cgggggagtctgaccctggacatcgcgcccagcgtcttccgctacaccatcgaagccagc
accttagtcctttacggagagcggcttggccttctgacccagcaaccaaaccctgacagc
ctgaactttatccacgcgctggaggccatgttcaagtccaccgtgcagctcatgtttgtg
ccccggcgcctgtcacggtggacgagcagcagcatgtggagggagcattttgaggcctgg
gactacatcttccagtatgccaacagagccatccagagaatctatcaggagctggccctc
ggccacccgtggcactacagcggcatcgtggcagagctgctgatgcgagcagacatgacc
ctggataccatcaaggccaacacaatcgacctcactgctgggagtgtggacacgacagcc
ttctccttgctgatgactctctttgagctggctcggaacccggaggtacagcagaccctg
cgccaggagagcctggtggctgaggcctggatctcagaaaatccccagagggccaccacg
gagctgcctttgttgcgggcggccctcaaggagaccttgaggctctaccccgtgggtatc
actttggagcgacaagtgagctcggacctggtgctgcagaactaccacatcccggccggg
acgctggtgaaggtcctactctattccctgggtcgaaaccccgccgtgttcgccaggccc
gagagctatcacccccagcgctggctggaccgccagggctctggaagcaggttcccgcac
ctggcctttggctttggagtgcgccagagtgcatgcgtgctctga

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