Ovis aries (sheep): 101110013
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Entry
101110013 CDS
T03117
Symbol
HSD17B7
Name
(RefSeq) 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform X3
KO
K13373
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:
1.1.1.62
1.1.1.270
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00100
Steroid biosynthesis
oas00140
Steroid hormone biosynthesis
oas01100
Metabolic pathways
oas04913
Ovarian steroidogenesis
Module
oas_M00101
Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
101110013 (HSD17B7)
00140 Steroid hormone biosynthesis
101110013 (HSD17B7)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101110013 (HSD17B7)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
101110013 (HSD17B7)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
101110013 (HSD17B7)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
DUF5798
Polysacc_synt_2
Eno-Rase_NADH_b
NAD_binding_10
Motif
Other DBs
NCBI-GeneID:
101110013
NCBI-ProteinID:
XP_004002763
EnsemblRapid:
ENSOARG00020001382
UniProt:
W5PMQ4
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Position
1:114354670..114385777
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AA seq
334 aa
AA seq
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MRKVVLITGASSGVGLALCRRLLEEDDALHLCLACRSMSKAEAVRTSLLASHPTAEVSIV
QVDVSSLPSVFQATKELKQRFQRLDYVYLNAGIMPNPQLNIKALFRGLFSRKVIHIFSTA
EGLLTQNDKITPDGLQEVFETNVFGHFILIQELESLLCHSESPSQLIWTSSRNAKKSNFS
LEDVQHSKGQEPYSSSKYAIDLLSVALNRNFNHQGLYSSVVCPGTMLTNLTYGILPPFVW
MLIMPIIWLLRFFANAFTLTPHNGTEALVWLFHQKPESLNPLVKYLSATTGFGSNYVTSK
KMDLEEDTAEKFYQKLLKLEKQIRVTIQKTNNQN
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atgcggaaagtggttttgatcaccggggcgagcagtggcgtgggcctagccctctgcagg
cggttgctggaagaagatgatgcgcttcacctgtgcttggcgtgcaggagcatgagcaaa
gcagaagctgtccgcacctctctgctggcctcccaccccactgctgaggtctctattgtg
caggtggatgtcagcagcctgccgtcggtgttccaggccaccaaggagctcaagcaaagg
tttcagagattagactatgtatatctaaatgctgggatcatgcctaatccacagctgaat
atcaaagcactttttcgtggtctcttttcaagaaaagtgattcatatattctccacagct
gaaggactgctgacccagaatgacaagattactcctgatgggctccaggaggtgtttgaa
accaatgtctttggccactttatcctgattcaggaactagaatctctcctatgtcacagt
gagagtccgtctcagctcatttggacatcatctcgcaatgcaaagaaatctaatttcagc
cttgaggatgtccagcacagcaaaggccaggagccctacagctcttccaaatacgctatt
gaccttctgagtgtggctttgaacagaaacttcaaccatcagggtctgtattccagtgta
gtgtgcccaggtacgatgctgaccaatttgacatatggaattctacctccctttgtgtgg
atgttaatcatgccaatcatatggctgttacgcttttttgcaaatgctttcacgttgaca
cctcacaatggaacagaagcactggtctggcttttccaccaaaagcctgagtctctcaat
cctctggtgaaatatctgagtgctaccactggctttggaagcaattatgtgacgtccaaa
aagatggacctagaggaagacactgctgaaaaattttaccaaaagttactgaaacttgaa
aagcagattagggtcaccattcaaaaaaccaataaccagaactga
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