Ovis aries (sheep): 101113677
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Entry
101113677 CDS
T03117
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00010
Glycolysis / Gluconeogenesis
oas00020
Citrate cycle (TCA cycle)
oas00620
Pyruvate metabolism
oas00785
Lipoic acid metabolism
oas01100
Metabolic pathways
oas01200
Carbon metabolism
oas01210
2-Oxocarboxylic acid metabolism
oas04066
HIF-1 signaling pathway
oas04922
Glucagon signaling pathway
oas05230
Central carbon metabolism in cancer
oas05415
Diabetic cardiomyopathy
Module
oas_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101113677 (PDHA2)
00020 Citrate cycle (TCA cycle)
101113677 (PDHA2)
00620 Pyruvate metabolism
101113677 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101113677 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101113677 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101113677 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101113677 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101113677 (PDHA2)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101113677 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
101113677
NCBI-ProteinID:
XP_004009736
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Position
6:complement(29301841..29303016)
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AA seq
391 aa
AA seq
DB search
MKKMLTAAVSRVLSGVTQKPASRVLVASCKYSNNATFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYKMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLTVRSILSELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNNEVCLTLYGDGAANQGQISEAYNMAALWNLPCIFICENNRYGMGTSVERAAAS
TDYYKRGNFIPGLRVDGMDILCVREATKFAADYCRSGKGPMLMELLTYRYHGHSMSDPGI
SYRTREEIQSVRSKSDPIMLLKDKMVNNKLASVEELKEIDAEVRKEIDDAAQFAMTDPEP
PLEELGHHIYSSNPPFDIRGANQWIKFQSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatgctgactgctgctgtctctcgcgtgctgtctggtgtcacccagaagccc
gctagcagagtgcttgttgcctcctgtaaatattcaaacaatgctaccttcgagattaag
aaatgtgatctttatcggttggaagagggcccccctgtcaccaccgtgctcacccgggag
gatggactcaaatactacaagatgatgcagactattcgtcgaatggaactgaaggcagat
cagttgtataaacagaaatttattcgtggtttctgtcacttgtgtgatggtcaggaagct
tgttgtgtgggtcttgaggctgggataaatcccaccgatcatgtcattacatcctatcgg
gctcacggcttatgttatacgcggggacttactgtccgatcaattctttcagagctgaca
ggacggagaggtggttgtgctaaaggaaaaggagggtccatgcatatgtatgccaagaac
ttctatgggggcaatggcattgtcggcgctcagggaccactgggagctggtattgctctt
gcctgtaaatacaaggggaacaacgaggtgtgtttgactctgtatggtgatggcgctgct
aatcagggtcagatatctgaagcttacaatatggcggctttgtggaatttaccttgcatt
ttcatctgtgagaataaccgctatggaatgggaacatctgtggagagagctgcagccagc
actgattactacaagagaggcaattttatccctggactaagagtagatggaatggatatt
ctatgtgttcgggaggcaactaagtttgcagctgactattgtagatctggaaaggggccc
atgctgatggagctgctgacataccgttatcacggacacagtatgagtgatcctggaatc
agttaccgtacacgagaagaaattcagagtgtaagaagtaagagtgatcctattatgctt
ctcaaagataaaatggtaaacaacaagcttgctagtgttgaagaactgaaggaaattgat
gctgaagtgaggaaagaaattgatgatgcagctcagtttgctatgactgatccagaacca
cctttggaagaattaggccatcacatctacagcagtaatccacctttcgatattcgtggt
gcaaatcagtggatcaagtttcagtcaatcagttaa
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