Ovis aries (sheep): 101114816
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Entry
101114816 CDS
T03117
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00061
Fatty acid biosynthesis
oas00620
Pyruvate metabolism
oas00640
Propanoate metabolism
oas01100
Metabolic pathways
oas04152
AMPK signaling pathway
oas04910
Insulin signaling pathway
oas04920
Adipocytokine signaling pathway
oas04922
Glucagon signaling pathway
oas04931
Insulin resistance
oas04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
101114816 (ACACB)
00640 Propanoate metabolism
101114816 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101114816 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
101114816 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
101114816 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101114816 (ACACB)
04922 Glucagon signaling pathway
101114816 (ACACB)
04920 Adipocytokine signaling pathway
101114816 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101114816 (ACACB)
04931 Insulin resistance
101114816 (ACACB)
Enzymes [BR:
oas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
101114816 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
101114816 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
101114816 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
101114816
NCBI-ProteinID:
XP_027812448
EnsemblRapid:
ENSOARG00020003924
LinkDB
All DBs
Position
17:complement(64000943..64133686)
Genome browser
AA seq
2431 aa
AA seq
DB search
MSDSKQVTKSKRKVSFTPSQEPIPASDGSQEPPQEGCNSSPLPETPRQAELASHKGPQDT
CQQRTSRSPPPQNPQGNPLSSDDASPARQANGSGTEGPEIPNTNDLSVPARPQGQRARTL
SREDRKQAHIKRQLMTNFILGSFDDNSSDEDSGAALFRQSSRKGSRASLGTLSLETAQAA
GETETCAPVIRPSMSGLHLARRGREQRKVDLHRDFTVASPAEFVARFGGHLVIEKVLIAN
NGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNH
NYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLHKHEIAFLGPPSEAMWALGDKIA
STIVAQTLQIPTLPWSGSGLTVEWAEHSLQEGQRISIPESIYNNGCVKDVDEGLEAAEKI
GFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPIFLMKLAQHARHLEVQILA
DQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVE
YLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESP
WGMTPISFETPSNPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVA
ATGGLHEFTDSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQ
SNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPAD
SLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYT
TYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYAVADGEHVEAGGSYAEIEV
MKMTTTLNVQESGRVKYIRRPGAVLEAGCMVARLELDDPSKVRPAEPFAGELPSQPTLPI
LGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRTLRHPSLPLLELQEIMT
SVSGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMN
TQSIVQLVQKYRSGARGYMKAVVLELLRKYLLVEHHFQQAHYDKCVINLREQLKPDMSQV
LDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQV
LIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKV
VCMASLEVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELL
RHSTELFMDSGFSPKSQRIGAMVAFQRFEDFVRNFDEVISCFANVPKDTPLFSKAQNSLY
SEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQ
EKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAA
RVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRT
DCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTTDSAIPI
RLFITNESGYYLDISLYKEVTDPRSGNILFHSFGSKQGPQHGMLINTPYVTKDLLQAKRF
QAQSLGTTYVYDFPEMFRQALFKMWHSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNE
VGMVAFKMRFKTLEYPEGRDIILISNDITFHIGSFGPGEDLLYLRASELARAEGIPKVYL
AANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDG
ESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVTCRALGIGAYLVRLGQ
RVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHYNGVSHVTVPDDFEGVCTIL
EWLSYMPKDNRSPVPVITPKDPTDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFD
QGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVEVVVPADPANLDSEAKIIQQAGQ
VWFPDSAYKTAQAINDFNREKLPLIIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQ
PVLIYIPPHAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYRKKDLVKT
IRRLDPVSKKLMEQLGMSELSDTDRKELEGQLKAREDLLLPMYHQVAVQFADLHDKAGRM
LEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETE
GAVKAYLWDNNQTVVRWLEEHWQAGEGLHSTIRENISCLKRDSALKTIRGLVQENPELAM
DSLVYISQHISPAERAQVIHLLSTVDGPAST
NT seq
7296 nt
NT seq
+upstream
nt +downstream
nt
atgtcagactccaagcaagtcaccaagagtaaacggaaagtgagcttcaccccgagtcag
gagccgattccagcctcagacggctcccaggagccaccgcaggaaggctgcaacagcagc
cctctgccagagacccctcgccaggctgagctggcctcccacaaaggaccccaagacacc
tgccagcagaggacctcccgatcacctccgccgcagaatccccaaggaaaccccctctcg
tctgatgacgcctccccagctcgacaagccaacgggtcagggactgaaggcccggagatc
ccaaataccaatgacctgtccgtgccagccaggccccagggccagcgagccagaaccctc
tccagagaagacaggaagcaggcacacatcaagagacagctgatgaccaacttcatcctg
ggctctttcgatgacaactcctccgatgaggactctggtgctgccctgttccgacagtct
tcccggaagggcagccgggccagcctggggacgctgtccttggagactgctcaggccgca
ggcgagactgagacctgcgcccccgttataaggcccagcatgtcagggctccacctcgca
agaaggggccgagagcagaggaaggtggacctgcacagagacttcactgtggcttcccct
gccgagttcgtcgcgcgctttggggggcatctggtcatcgagaaggtgctcatcgccaac
aacggtattgccgccgtgaaatgcatgcgctccatccgcaggtgggcctatgagatgttc
cgaaatgagcgggccatccggttcgtagtcatggtaacgccagaggacctcaaggccaac
gcagagtatatcaagatggcagatcagtatgtccccgtcccaggagggcccaacaaccac
aattacgccaacgtggagctgattgtggacatcgccaagaggatccccgtgcaggcggtg
tgggctggttggggccatgcttctgaaaaccccaaacttccggagctcctgcacaagcac
gagattgctttcctaggccctcccagcgaggccatgtgggcactgggagacaagatcgcc
tccaccatcgtggcccagactctgcagatcccaacgctgccctggagcggaagtggtctg
acggtggagtgggcggaacacagtctacaggaagggcaaaggatcagcatcccagagtcc
atctacaacaacggttgcgtgaaagatgtagatgaaggcttggaggcagcagaaaaaatt
ggttttcccttgatgatcaaagcttctgaaggcggcggagggaaaggaatccggaaggca
gagactgctgaggacttccccatcctgttcagacaagtgcagagcgagacccctggttcg
ccaatcttcctcatgaagctggcccagcacgcccggcacctggaggtccagatcctcgcc
gaccagtacgggaacgcagtgtccctgttcgggcgcgactgttccatccagcggaggcac
cagaagatcatagaggaggcgccggccaccattgccacgccggcagtgttcgagttcatg
gagcagtgtgccgtgcgcctggccaagacagtgggctatgtgagcgcggggaccgttgag
tacctctacagccaggacggcagcttccacttcttggagctgaatccccgcctgcaggtg
gaacatccctgcacggagatgattgcggatgtcaacctgcccgctgcccagctgcagatc
gccatgggtgtgccgctgcaccggctgaaggatatccggcttctgtacggagagtccccg
tgggggatgacgcccatttcttttgagacccctagcaaccctcccattgcccgaggccac
gtcattgcagccagaatcaccagcgaaaacccagatgaggggtttaagccaagctccgga
acagtccaagaattgaatttccgtagcagcaagaacgtgtggggttacttcagcgtggct
gcgactggcggcttacacgaatttacggattcccagtttgggcactgcttctcctggggg
gagaaccgggaagaggctatttcgaacatggtggtggctttgaaggaactatccatccgg
ggcgacttcaggacaactgtggaatatctcaccaaccttctggagactgagaactttcag
agcaacgacattgacaccagctggttggataacctcattgccgagaaagtgcaggctgag
aagccagatatcatgctcggggtcgtgtgcggagccttgaacgtggccgactccatgttt
agaacatgcatgacggatttcctacattcactggaaaggggccaagtcctccctgcagac
tctctgctgaacatcgtggacgtggaattaatttatggaggcgtcaagtacatcctcaag
gtggcccggcagtctccgaccatgtttgtcctcatcatgaacggctctcacattgagatt
gacgcccatcggctcaacgatggggggctactgctgtcctgcagcggcaacagctacacc
acctacatgaaggaggaggtggacagttaccgaatcaccattggtaacaagacgtgcgtg
tttgagaaggagaatgatcccacagtcctgagatccccttcggctgggaagctggtgaag
tacgccgtggcggacggggaacacgttgaagctgggggcagctacgccgagatagaggtc
atgaagatgaccacaaccctgaacgtgcaagaaagtggccgggtgaagtatatcaggcgc
ccgggggctgtgctggaagctggctgcatggtggccaggctggagctcgatgacccttct
aaagtgcgcccggctgagccgtttgcgggggagctcccctcacagccaacgctgcccatc
ctcggagagaagctgcaccaggtttttcacagcgtcctggaaaatctcaccaacatcatg
aatggctactgtctgccagaacctatttttagcatcaagctgaaggactgggtgcagaag
ctcctgaggaccctccggcacccgtcgctgccgctgctggagctgcaggagatcatgacc
agtgtgtcgggccgcatccccgcccctgtggagaaggccgtccgcagggtgatggcccag
tatgccagcaacatcacctcggtgctgtgccagttccccagccagcagatagccaccatc
ctggactgccacgcggccaccctgcagcggaaggccgaccgggaggtcttcttcatgaac
acccagagcattgtacagctggtccagaagtaccgcagcggggcccgcggctacatgaag
gcggtggtgttggagctcctgcggaaatacttgctggttgagcaccatttccaacaagcc
cactacgataagtgtgtgataaacctccgggagcagctgaagccagacatgtcccaggtg
ttggactgcatcttctcccactcacaggtggccaagaagaaccagctggtgatcatgctg
attgatgagctctgtggcccagacccatccctgtccgatgagctgacctccatccttgac
gagctgacccagctgagcaaaagcgagcactgcaaggtggccctcagagccaggcaggtc
ctgattgcctcccacctcccctcctacgagctgaggcacaaccaagtggagtccattttc
ctatctgccatcgacatgtatggccaccagttctgcccagaaaacctcaagaaattaata
ctctcagaaacaaccatctttgatgtgctgcccactttcttctaccatgctaacaaagtg
gtttgcatggcatccttggaggtttacgtgcggaggggctacatcgcctatgagctaacc
agcctgcagcaccgccagttcccagatggcacctgtgtggtggaattccagttcatgctg
ccctcctcccacccgcaccggatgaccgtgcccatcagtgtcaccaacccggagctgctg
agacacagcacggagctcttcatggacagtggcttctcccccaagtcccagcgaatcggg
gccatggtcgccttccagagattcgaggatttcgtcaggaactttgatgaggtcatctcc
tgctttgccaacgtgcccaaggacaccccccttttcagcaaggcccagaattccctgtac
tctgaggacgacagcaagagcctccgagaggagccaatccacatcctgaacgtggccctc
cagcacgcggaccaccaggaggatgagcagctggtgcccattttccgaacatttgtgcag
tccaagaagaacatccttgtggagtgtggactccgaagaatcacattcctgattgcccaa
gagaaagaatttcccaagtttttcacattcagagcaagagatgagtttgcagaagatcgc
atctaccgtcacttggagccagccctggccttccagctggagctcagccggttgcgaaac
tttgacgtgaccgccatgccctgcgccaaccacaagatgcacctgtacctgggcgccgcc
agagtgaaggagggtgccgaggtcacggaccacaggttcttcatccgggtcatcatcagg
cactcggacctgatcaccaaggaagcctccttcgagtacctccagaacgagggcgagcgg
ctgctcctggaggccatggacgagctggaggtggcattcaataacaccagcgtgcgcacc
gactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccctccaagatc
gaggagtcggtgcggtccatggtgatgcgctacggcagccggctgtggaagctccgcgtg
cttcaggctgaggtcaagatcaacatccgtcagaccaccaccgacagcgccatccccatc
cgcctcttcatcaccaacgagtcaggctactacctggacatcagcctctacaaggaagtg
acggaccccagatctgggaacatcttgtttcactcctttggcagcaagcaaggcccccag
catgggatgctgatcaacactccctacgtcaccaaggatctgcttcaggccaagcgattc
caggcccagtccctaggcaccacctacgtgtatgacttcccagaaatgttcaggcaggct
ctttttaaaatgtggcactccccagacaaataccccaaagacatcctgacgtacaccgaa
ctcgtgctggatccgcagggccagctggtggagatgaaccgacttcctggaggaaatgag
gtgggcatggtggccttcaaaatgaggtttaagaccctcgagtacccagaagggcgtgac
attatcctcatcagcaatgacatcaccttccacattggatccttcggccccggagaggac
cttctgtacctgcgggcgtccgagctggcccgggccgagggcatccccaaagtctacctc
gcggccaacagtggggcccgtatcggcctggcagaggagatcaagcacatgttccaggtg
gcttgggtggacccggaagacccccacaagggaattaaatacctgtacctgaccccccaa
gactacaccagaatcagctccctgaactccgtccattgtaagcacgtggaggaagatgga
gaatccaggtatgtcatcacggacatcatcgggaaggaggagggcctgggcgtagagaac
ctgaggggctcaggcatgattgctggggagacctcccaggattacgacgagatcgtcacc
atcagcatggtgacctgccgggccctcgggatcggggcctacctggtgaggctgggccag
cgagtgatccaggtcgagaattcccacatcatcctcacgggggcgacggctctcaacaag
gtcctgggcagagacgtttacacgtccaacaaccagctaggaggtgtgcagatcatgcat
tacaatggcgtctcacatgtcaccgtgccggatgacttcgagggtgtttgtaccatcctg
gagtggctgtcctatatgccaaaggataatcgcagcccagtcccagtcatcacacccaag
gaccccactgacagagaaattgaattccaaccatctcgcgggccctacgacccccggtgg
ctacttgcaggaagacctcacccaactctgaagggatcctggcagagtggattctttgac
cagggcagtttcaaggagatcatggtgccctgggcccagactgtggtgacgggacgagca
aggctggggggcatccctgtcggagtgattgctgcagagacgcggacggtggaggtggtc
gtgcccgccgaccctgccaacctggattctgaggccaagataatccagcaggctggccaa
gtgtggttcccagactcagcctataagacagcccaggccatcaatgatttcaatcgggag
aagctgcccctgatcatatttgccaactggagggggttctccgggggcatgaaagacatg
tacgaccaggtgctaaagttcggagcctacatcgtggacggcctccggaagtacagacag
cctgtcctgatctacatcccaccccacgcggaggtccggggcggctcctgggcggtcatg
gacacctccatcaacccgctgtgcatagagatgtatgcggacagagagagcagagcgagt
gttctggagccagagggaacagtggagattaagtaccggaagaaagatctggtgaagacc
atcagaagactcgaccctgtttccaagaagctcatggagcagcttggaatgtctgagctc
tcagacacggaccgcaaggagctggagggccagctgaaggcccgggaggacctgttgctg
cccatgtaccaccaggtggcggtgcagttcgccgacctccacgacaaggcgggcaggatg
ctggagaagggcgtcatttacgacatcctggagtggaagaccgcccgcagcttcctgtac
tggcgcctgcgccgcctgctgctggagagccaggtgaagcaggaggtcctgcgggcctgc
cccgagctcagccacatgcacgtgcagtccatgctgcgccgctggttcgtggagacggag
ggcgcagtcaaggcctacctgtgggacaacaaccagacggtggtgcggtggttggaggag
cattggcaggcaggcgaggggctgcactccaccatccgcgagaacatctcgtgcctgaaa
cgggactccgcccttaagaccatccggggcctggttcaagaaaaccctgagctggccatg
gactcactggtgtacatcagccagcacatcagccccgccgagcgggcccaggtcattcac
ctcctgtccaccgtggacggcccggcctctacctga
DBGET
integrated database retrieval system
