Ovis aries (sheep): 101115956
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Entry
101115956 CDS
T03117
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01522
Endocrine resistance
oas04010
MAPK signaling pathway
oas04015
Rap1 signaling pathway
oas04068
FoxO signaling pathway
oas04071
Sphingolipid signaling pathway
oas04114
Oocyte meiosis
oas04148
Efferocytosis
oas04218
Cellular senescence
oas04261
Adrenergic signaling in cardiomyocytes
oas04370
VEGF signaling pathway
oas04380
Osteoclast differentiation
oas04550
Signaling pathways regulating pluripotency of stem cells
oas04611
Platelet activation
oas04613
Neutrophil extracellular trap formation
oas04620
Toll-like receptor signaling pathway
oas04621
NOD-like receptor signaling pathway
oas04622
RIG-I-like receptor signaling pathway
oas04625
C-type lectin receptor signaling pathway
oas04657
IL-17 signaling pathway
oas04658
Th1 and Th2 cell differentiation
oas04659
Th17 cell differentiation
oas04660
T cell receptor signaling pathway
oas04664
Fc epsilon RI signaling pathway
oas04668
TNF signaling pathway
oas04670
Leukocyte transendothelial migration
oas04714
Thermogenesis
oas04722
Neurotrophin signaling pathway
oas04723
Retrograde endocannabinoid signaling
oas04728
Dopaminergic synapse
oas04750
Inflammatory mediator regulation of TRP channels
oas04912
GnRH signaling pathway
oas04914
Progesterone-mediated oocyte maturation
oas04917
Prolactin signaling pathway
oas04926
Relaxin signaling pathway
oas04932
Non-alcoholic fatty liver disease
oas04933
AGE-RAGE signaling pathway in diabetic complications
oas04935
Growth hormone synthesis, secretion and action
oas04936
Alcoholic liver disease
oas05014
Amyotrophic lateral sclerosis
oas05020
Prion disease
oas05022
Pathways of neurodegeneration - multiple diseases
oas05132
Salmonella infection
oas05133
Pertussis
oas05135
Yersinia infection
oas05140
Leishmaniasis
oas05142
Chagas disease
oas05145
Toxoplasmosis
oas05152
Tuberculosis
oas05161
Hepatitis B
oas05163
Human cytomegalovirus infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05169
Epstein-Barr virus infection
oas05170
Human immunodeficiency virus 1 infection
oas05171
Coronavirus disease - COVID-19
oas05205
Proteoglycans in cancer
oas05208
Chemical carcinogenesis - reactive oxygen species
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05415
Diabetic cardiomyopathy
oas05417
Lipid and atherosclerosis
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101115956 (MAPK12)
04015 Rap1 signaling pathway
101115956 (MAPK12)
04370 VEGF signaling pathway
101115956 (MAPK12)
04668 TNF signaling pathway
101115956 (MAPK12)
04068 FoxO signaling pathway
101115956 (MAPK12)
04071 Sphingolipid signaling pathway
101115956 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101115956 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
101115956 (MAPK12)
04218 Cellular senescence
101115956 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101115956 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101115956 (MAPK12)
04613 Neutrophil extracellular trap formation
101115956 (MAPK12)
04620 Toll-like receptor signaling pathway
101115956 (MAPK12)
04621 NOD-like receptor signaling pathway
101115956 (MAPK12)
04622 RIG-I-like receptor signaling pathway
101115956 (MAPK12)
04625 C-type lectin receptor signaling pathway
101115956 (MAPK12)
04660 T cell receptor signaling pathway
101115956 (MAPK12)
04658 Th1 and Th2 cell differentiation
101115956 (MAPK12)
04659 Th17 cell differentiation
101115956 (MAPK12)
04657 IL-17 signaling pathway
101115956 (MAPK12)
04664 Fc epsilon RI signaling pathway
101115956 (MAPK12)
04670 Leukocyte transendothelial migration
101115956 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
101115956 (MAPK12)
04914 Progesterone-mediated oocyte maturation
101115956 (MAPK12)
04917 Prolactin signaling pathway
101115956 (MAPK12)
04926 Relaxin signaling pathway
101115956 (MAPK12)
04935 Growth hormone synthesis, secretion and action
101115956 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101115956 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
101115956 (MAPK12)
04723 Retrograde endocannabinoid signaling
101115956 (MAPK12)
04722 Neurotrophin signaling pathway
101115956 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101115956 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
101115956 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
101115956 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101115956 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
101115956 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101115956 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101115956 (MAPK12)
05161 Hepatitis B
101115956 (MAPK12)
05171 Coronavirus disease - COVID-19
101115956 (MAPK12)
05163 Human cytomegalovirus infection
101115956 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
101115956 (MAPK12)
05169 Epstein-Barr virus infection
101115956 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
101115956 (MAPK12)
05135 Yersinia infection
101115956 (MAPK12)
05133 Pertussis
101115956 (MAPK12)
05152 Tuberculosis
101115956 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101115956 (MAPK12)
05140 Leishmaniasis
101115956 (MAPK12)
05142 Chagas disease
101115956 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101115956 (MAPK12)
05020 Prion disease
101115956 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
101115956 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101115956 (MAPK12)
05418 Fluid shear stress and atherosclerosis
101115956 (MAPK12)
05415 Diabetic cardiomyopathy
101115956 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101115956 (MAPK12)
04932 Non-alcoholic fatty liver disease
101115956 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
101115956 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
101115956 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101115956 (MAPK12)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
101115956 (MAPK12)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
101115956 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
Motif
Other DBs
NCBI-GeneID:
101115956
NCBI-ProteinID:
XP_027824053
EnsemblRapid:
ENSOARG00020007611
LinkDB
All DBs
Position
3:complement(225541826..225549778)
Genome browser
AA seq
392 aa
AA seq
DB search
MSSPSPARKGFYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRVQFLVYQTLKGLKYIHAAGVIHRDLKPSNLAVNEDCELKGPLCPPPPLTLA
VDSGLRPGPAGRQRDDRLRGDPVVPRARGHLELDALHADGPRSPHAGASVSVDIWSVGCI
MAEMITGKTLFKGNDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFAS
VLTNASPLAVSLLEKMLVLDAEQRVTAAEALAHPYFESLHDTEDEPQAQKYDESFDDVDR
TLDEWKRVTYKEVLSFKPPRQLGAKASKETAL
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atgagctccccgtcgcccgcccgcaagggcttttatcgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccaggatctgcagcccgtgggctccggcgcctacggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctgaagcac
atgcgccacgagaacgtgattgggctgctggacgtgttcacgcccgatgagacactggat
gacttcacggacttctacctggtgatgccgttcatgggcaccgacctgggaaagctcatg
aagcacgagaagctgagcgaagaccgggtgcagttcctcgtctaccagacgcttaagggg
ctgaagtacatccacgctgctggcgtcatccatagggacttgaagcccagcaacctggct
gtgaacgaggactgtgagctgaagggaccgctttgccccccaccccctctgactctggct
gtagattctggacttcggcctggcccggcaggcagacagcgagatgaccggctacgtggt
gacccggtggtaccgcgcgcccgaggtcatcttgaactggatgcgctacacgcagacggc
ccgcggagccctcatgcaggggcttctgtctcagtggacatctggtccgtgggctgcatc
atggctgagatgatcacagggaagacgctcttcaaaggcaacgaccacctggaccagctg
aaggagatcatgaaggtgacagggacgcctcccgcggagtttgtgcagaggctgcaaagt
gatgaggccaagaactacatgaagggcctccctgagctggagaagaaggattttgcctcc
gtcctgaccaacgcgagccccctggccgtgagcctcctggagaaaatgctggtgctggac
gcagagcagcgggtgacggcggccgaggcactggcccatccctacttcgagtcactgcac
gacacggaggacgagccccaggcccagaagtacgatgagtcctttgacgacgtggaccgc
acgctggatgagtggaagcgtgtcacatataaagaggtgctcagcttcaagcctccccgg
cagctgggggccaaggcctccaaggagacagccttgtga
DBGET
integrated database retrieval system