Ovis aries (sheep): 105606468
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Entry
105606468 CDS
T03117
Symbol
TPO
Name
(RefSeq) thyroid peroxidase isoform X1
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00350
Tyrosine metabolism
oas01100
Metabolic pathways
oas04918
Thyroid hormone synthesis
oas05320
Autoimmune thyroid disease
Module
oas_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
105606468 (TPO)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
105606468 (TPO)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
105606468 (TPO)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
105606468 (TPO)
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Gene cluster
GFIT
Motif
Pfam:
An_peroxidase
EGF_CA
Sushi
FXa_inhibition
EGF_3
cEGF
LRRNT
Motif
Other DBs
NCBI-GeneID:
105606468
NCBI-ProteinID:
XP_027819824
EnsemblRapid:
ENSOARG00020001091
LinkDB
All DBs
Position
2:765784..800004
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AA seq
923 aa
AA seq
DB search
MRARAVLGVVLAVTCAGAIFSFLLRPGGLLWGDTEESQVRGIVEASRLLVDKSIYAAMRR
NLHKREVISPSQLLSFSKLPEPTSRAASRAAEVMEASVQEAVRRGHLQSGPSRLPTDALS
EGLLSAIANLSGCLPHMLPPRCPATCLVSKYRLITGACNNRDHPRWGASNTALARWLPPA
YEDGISEPRGWNPHFLYRGFPLPPVREVTRRIIHASNEAVTGDDRYSDLLTAWGQYIDHD
VAFTPQSVGPPAPGAGADCQLTCEPQSPCFPIQLPANAAGPACLPFHRSTAACGTGTQGA
VFGNLSAANPRQQMNGLTSFLDASTVYGSSAASERRLRNWTSAEGLLRVNVRYRDAGRAF
LPFAPPSAPPACAPPPGAPGARAPCFLAGDGRASEVPALAALHTLWLREHNRLASALKAL
NAHWSADTAYQEARKVVGALHQIITLRDYVPRILGPEAFGRHVGPYRGYDPSVDPSVSNV
FSTAAFRFGHATIHPLVRRLDARFQEHPGSRLPLRDAFFRPWRLLEEGGVDPVMRGLLAR
AAKLQVQDQLLNEELTERLFVLSDAGTLDLASINLQRGRDHGLPGYNEWRQFCGLSRLET
RADLGAATANGSMADRILALYGHPDNIDVWLGGLAESFLPGARTGPLFACLVGKQMKALR
DGDRFWWEHHGVFTEAQRRELGRHSLSRVICDNTGLTHVPRDAFRVGQWPQDFESCDRIP
GMDLRAWREAPPPDDACGFPDNVENGGFLLCNESGRRLLVFSCHHGFQLQGPEQLTCTRR
GWDSQPPVCRDINECEDGVDPPCHASARCKNTKGGFRCECHDPHVPGEDGRTCVDSGRLP
RASVVSLVLGAVLVCGLAGLTWTVVCRWMLANPKSSLPPVEGEGEGPSWLGRGKPRDVCA
PPDAPAGLAEQGPACGPQVLLCK
NT seq
2772 nt
NT seq
+upstream
nt +downstream
nt
atgcgggcacgggccgtgctgggcgtggtgctggccgtcacctgtgccggagccatcttc
tccttcctcctgagacccgggggcctcctttggggagacaccgaggagtctcaggtcagg
ggcatcgtggaggccagcaggctcctggtggacaagtccatctacgctgcgatgagaaga
aacctccacaaaagggaagtcatttccccatcgcaacttctgtctttttccaaactccct
gagcccacgagccgagctgcatcccgggcggcggaggtcatggaggcctcggtgcaggag
gcggtgaggcggggtcacctgcagtctggaccctcccggctgcccacagatgctctctcg
gaggggctgctgagcgcgatcgcaaacctgtccggatgcctgcctcacatgctgccgccc
agatgtccggccacctgcctggtcagcaagtacaggctcatcacgggcgcctgcaacaac
agagaccacccgcgctggggagcctccaacacagcgctggccagatggctgccccccgcc
tacgaggacggcatcagtgagccccgaggctggaacccccacttcctgtacagaggcttt
cccctgccgccggtccgggaggtgaccagacgcatcatacacgcctccaatgaggctgtg
acgggggacgaccggtactctgacctcctgacggcctggggccagtacatcgaccacgac
gtggccttcacgccgcagagcgtgggcccccctgcccccggggcgggggccgactgccag
ctgacctgcgagccccaaagcccatgctttcccatacagctccccgcgaacgctgcgggc
cccgcctgtctgccctttcaccgctccacggccgcctgcggcaccgggacccaaggcgcc
gtgttcggcaacctgtctgccgccaacccgcgccagcagatgaacgggctgacctcgttc
ctggacgcgtccaccgtgtacggcagctccgcggcctcggagcggcggctgcggaactgg
accagcgccgaggggctgctgcgcgtcaacgtgcgctaccgggacgcgggccgcgccttc
ctgcccttcgcgccgccgtccgcgcccccggcttgcgctcccccgcccggcgcgcccgga
gcccgcgcaccctgcttcctggccggcgacggccgcgccagcgaggtccccgccctggcg
gccttgcacacactgtggctgcgagagcacaaccgcctggcctccgcgctcaaggccctc
aacgcgcactggagcgcggataccgcctaccaggaggcgcgcaaggtggtgggcgcgctg
caccagatcatcacgctgcgcgattatgtccccagaatcctgggccccgaggcctttgga
cggcacgtgggcccctacagaggctacgaccccagcgtggacccctccgtgtccaacgtg
ttctccacggcggccttccgcttcggccatgccaccatccacccactggtgcggcggctg
gacgcccgcttccaggagcacccggggtcccgcctgccgctcagggacgccttcttccgg
ccctggcggctcctcgaggaaggcggcgtggaccccgtcatgcggggtctgctggcgaga
gcggccaagctgcaggtgcaggaccagctgctgaacgaggagctgacggagaggctcttc
gtgctctcggacgcggggaccctggacctggcgtccatcaacctgcagcggggccgggac
cacggcctgccagggtacaatgagtggcggcagttctgcggcttgtccaggctggagacc
cgggccgacctgggcgcggccaccgccaacgggagcatggccgacagaatcctggccctg
tatgggcaccccgacaacatcgacgtgtggctgggcggcctggcggagagcttcctcccg
ggggcgcggactggtccgctgttcgcctgcctcgtgggaaagcagatgaaggccctgagg
gatggcgaccggttctggtgggagcaccacggggtgttcaccgaggcccaacggcgcgag
ctgggccggcactcgctgtcccgcgtcatctgcgacaacacgggcctcacccacgtgccc
cgcgacgccttccgggtggggcagtggccccaggacttcgagtcatgtgaccgtatcccg
gggatggacctgcgcgcctggcgggaagcccctcctccagacgacgcctgtggcttcccg
gacaacgtggagaacgggggcttcctgctctgcaacgagtctgggcggaggctgctggtg
ttctcctgtcatcacggattccagctccaagggcctgagcagctcacctgcacccggcgc
ggctgggactcccagcccccggtctgtcgagacatcaacgagtgtgaggatggagtggac
cccccctgccacgcgtccgcgcggtgcaagaacaccaagggtggcttccggtgtgagtgc
cacgacccccacgtgcccggcgaggacggcaggacctgtgtggactccgggaggctcccg
cgggcgtctgtggtctccctggtgctaggcgccgtgctcgtctgcggtctggctggcctc
acctggacggtggtttgcaggtggatgctcgccaaccctaagtcctcgctgccgcccgtg
gagggagagggagaaggaccttcctggctgggccgtgggaaaccccgggacgtgtgcgct
cccccggacgctcctgcggggcttgcagagcagggcccggcctgtggaccccaagtcctc
ctctgcaagtag
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