Ovis aries (sheep): 443186 Help Entry 443186            CDS       T03117                                  Symbol ACACA Name (RefSeq) acetyl-CoA carboxylase 1   KO K11262   acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism oas  Ovis aries (sheep) Pathway oas00061   Fatty acid biosynthesis oas00620   Pyruvate metabolism oas00640   Propanoate metabolism oas01100   Metabolic pathways oas01212   Fatty acid metabolism oas04152   AMPK signaling pathway oas04910   Insulin signaling pathway oas04922   Glucagon signaling pathway oas04936   Alcoholic liver disease Module oas_M00082   Fatty acid biosynthesis, initiation Brite KEGG Orthology (KO) [BR:oas00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     443186 (ACACA)    00640 Propanoate metabolism     443186 (ACACA)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     443186 (ACACA)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     443186 (ACACA)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     443186 (ACACA)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     443186 (ACACA)    04922 Glucagon signaling pathway     443186 (ACACA)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     443186 (ACACA) Enzymes [BR:oas01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      443186 (ACACA)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      443186 (ACACA)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      443186 (ACACA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 MetallophosN Motif Other DBs NCBI-GeneID:  443186 NCBI-ProteinID:  NP_001009256 EnsemblRapid:  ENSOARG00020023744 UniProt:  Q28559 LinkDB All DBs Position 11:complement(13136279..13424655) Genome browser AA seq 2346 aa AA seqDB search MGEPSSLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG GPNNNNYANVELILDIARRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL GDKIASSIVAQTAGIPTLPWSGSGLCVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKA AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSA GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV LSAHTLLNTVDVELIYEGEKIVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYA EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVEGLMKTLRDPSLPLLELQ DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM SFSSNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLV EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQA FLPPPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPDGRDIIVI GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPID RVIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSARE RKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST MDSPST NT seq 7041 nt NT seq  +upstreamnt  +downstreamnt atgggtgaaccttcttccttggccaaacctctggagctgaaccagcactcccgattcata attggctccgtgtctgaagataactcggaggatgagattagcaacctggtgaagctcgac ctactggaggagaaggagggctctctgtcaccagcctctgtcagctcagacacgctctct gacttggggatctcgagcctccaggatggtttggccttacacatgagatccagcatgtct ggtttgcacctagtcaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc actgtagcctcgccagcagaatttgttactcgttttggtgggaataaagtgattgagaag gttctcatcgccaacaatggcattgcagctgtgaaatgcatgagatccatccgccggtgg tcttatgagatgtttcgaaatgagcgtgcgatccggtttgttgtcatggtcacacctgaa gacctgaaagccaacgcagaatacattaagatggcagatcactacgtgccagtgccagga ggccccaacaacaacaactatgcaaatgtggagttaattcttgacattgctagaaggatc ccagtgcaagcagtttgggctggctggggtcatgcttctgagaatcccaagctcccagaa cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaagccatgtgggctttg ggggataagattgcatcttccatagtggctcaaactgctggtatcccaactcttccatgg agtggcagtggtctttgtgtggactggcacgaaaatgatttttcaaaacgaattttaaat gttcctcaggaactatatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggca gcggaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaagggg atcagaaaagtcaacaacgcggatgacttccctaacctcttccgacaggttcaagctgaa gttcctggatctcctatctttgtcatgagactagctaaacagtctcgtcatctggaggtg cagatcttagcagatcagtatggcaatgctatctctctgttcggtcgtgattgctctgtg caacgcaggcatcagaagattattgaagaagctcctgccgctattgctactccagcagta tttgaacatatggaacagtgtgcggtgaagcttgccaggatggttggttacgtgagtgcg gggactgtggaatacctctacagccaggatggcagcttctactttctggaactgaaccct cggctacaggtggagcacccctgtacagagatggtggccgatgtcaacctccctgccgcg cagctccagattgccatggggatccctctgtacagaatcaaggatatccgtatgatgtac ggggtctctccctggggcgatgctcccattgattttgaaaattcggctcacgttccttgc ccaaggggccatgttattgctgctcgtatcactagtgaaaatccagatgaggggtttaag cccagctcaggaacagttcaagagctgaattttcgcagcaataagaacgtttggggttat ttcagtgttgctgctgcaggagggcttcatgaatttgctgattctcagtttggtcactgc ttttcctggggagaaaaccgagaggaagcaatttcaaacatggtggtggctttgaaggag ctgtccatccggggcgacttccggaccacagtcgagtacctgatcaaactgctggagacg gaaagcttccagttgaataggattgacacgggctggctggacagactgatagcagaaaaa gtacaggcggagcgacctgacaccatgctgggagttgtctgtggggctctccacgtggca gacgtgagcctgcggaatagcatctccaacttccttcactccttagagaggggtcaagtc ctctctgctcatacacttctgaacacagtagatgttgaacttatctatgagggagagaag atagtactgaaggtgactcgacagtccccaaactcctacgtggtgatcatgaacggctcg tgcgtggaagttgacgtgcatcgactgagcgacggtggactgctcttgtcctatgacggc agcagttacaccacatacatgaaggaggaggtggatagatatcgcatcacaattggcaat aaaacttgcgtgtttgagaaggaaaatgacccttcagtgctgcgctcaccctctgctggg aagttaatccagtacattgtggaggatggaggccatgtgtttgctggccagtgctatgct gagatcgaggtgatgaagatggtaatgaccttaacagccgcagagtctggctgtatccat tacgtcaagcggcctggagcagctcttgacccgggctgtgtaatagccaaaatgcaactg gacaaccccagcaaggtccagcaggctgagcttcacacaggcagtctgccacggatccag agcacagcactcagaggcgagaagctccatcgagtgttccactatgtcctggataatctg gtcaacgtgatgaatggatactgccttccagatcctttctttagcagcagggtgaaagac tgggttgaaggcttgatgaagaccctcagggacccctccttgcctctcctagaattgcag gatatcatgaccagcgtctctggtcgtatcccacccaacgtggaaaagtctatcaagaag gaaatggctcagtatgccagcaacatcacatccgtcctctgccagtttcccagccagcag attgccaacatcctagatagccatgcagccacactgaaccggaaatctgaacgggaagtc ttcttcatgaacactcagagcatcgtccagctggtgcagaggtaccgcagtggcatccga ggacacatgaaggctgtggtgatggacctgctgcggcagtacctgcgagtagagactcag ttccagaacggtcactatgacaaatgcgtgttcgccctccgggaggagaacaagagtgat atgaacactgtactgaactacatcttctctcacgctcaagtcaccaagaagaatcttctg gtcaccatgcttatcgatcagctgtgtggccgggaccccaccctcactgatgagctgctg aatatcctcacggagctaactcaactcagcaagaccaccaacgcgaaggtggcactccga gcacgccaggttcttattgcttcccatttgccatcatatgagcttcgccacaaccaagtc gagtctatcttcctgtccgccattgacatgtacggacatcagttctgcatcgagaacctg cagaaactcatcttgtccgaaacgtcgatttttgatgtcctgccaaacttcttctatcac agcaaccaggtcgtgaggatggcagctctggaggtgtatgttcgaagggcttatatcgcc tatgaacttaatagcgtacaacaccggcagctgaaggacaacacctgcgtggtggaattc cagttcatgctgcccacatcacatccaaacagagggaacatccccacgctaaacagaatg tccttctcctccaacctcaaccactacggcatgactcacgtagccagtgtcagcgacgtg ctgctggacaacgcgttcactccgccgtgtcagcggatgggcgggatggtctcttttcgg acctttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgattcccca ccccaaagcccgacattccctgaggcaggtcacacgtctctgtatgatgaagacaaggtc cccagggatgaaccaattcacattttgaatgtggctatcaaaacagactgtgacatcgag gatgacagtctagcagctatgttccgagagtttacccagcaaaacaaagctaccctggtt gaacatgggatccgacgccttactttcctggttgcacaaaaggatttcaggaaacaggtc aactatgaagtggatcagagatttcatagagaatttcctaaatttttcacgttccgagca agggataagtttgaggaagatcgtatctatcgtcacctggagcctgccctagctttccag ttggagctgaaccggatgagaaattttgaccttactgccatcccatgtgccaatcacaag atgcacttgtatctcggggcagccaaggtggaagtgggcacagaagtgacagactacagg ttctttgtccgtgcaatcatcaggcattcggatctggtcaccaaggaagcttcctttgag tatctacaaaatgaaggggagcggctcctcctggaagccatggatgagctggaagtcgcc tttaacaatacaaatgtccggaccgactgcaaccacatcttcctcaactttgttcctaca gtcatcatggacccatcgaagattgaggaatccgtgcggagcatggtgatgcgctatgga agtcggctgtggaagctgcgtgtcctccaggcagaactgaaaatcaacattcgcctgacc ccaactggaaaagcaattcccatccgcctcttcctgacgaatgagtctggctattacttg gacatcagcctgtacaaggaagtgactgattccaggacagcacagatcatgtttcaggca tatggagacaaacagggaccattacatggaatgttaatcaacactccgtatgtgaccaaa gacctgcttcagtccaagaggttccaggcacagtccttagggacaacatacatatatgac atcccagaaatgtttcggcagtccctgatcaaactctgggaatctatgtcctctcaagca ttccttccaccgccccctctgccttcagacatactgacgtacactgagctcgtgttggat gatcaaggtcaactggttcacatgaacaggcttccaggaggaaatgagattggcatggta gcttggaaaatgacccttaaaagtccagaatatccagatggccgagatatcattgttatt ggcaatgacatcacttaccgaatcgggtcctttggaccccaggaggatttgctgtttctc agagcttctgagcttgccagggcagagggcatcccacgcatctatgtagcagccaatagt ggagcaagaattggactggcagaggaaattcgtcatatgttccatgtggcctgggtagat cctgaggatccttacaagggatacaaatatttatatctgacccctcaagattacaagaga gtcagtgctctcaactctgtccattgtgaacatgtggaagatgaaggagaatccaggtac aagataactgacattattgggaaggaagaaggacttggagcagagaaccttcgagggtct ggaatgattgctggggaatcctctttggcctacgacgagatcatcaccatcagcctggtt acgtgcagggccattgggattggggcttacctcgtccgactgggacagagaaccatccag gtcgaaaattctcacttaatcctgacaggagctggggccctcaacaaagtcctcgggagg gaagtatacacctcgaacaaccagctggggggcattcagatcatgcacaacaacggggtg acgcacagcaccgtctgtgatgactttgagggggtgttcaccgtcctgcactggctgtct tacatgccgaagagtgtatacagttcagttcctctcctgaattccaaggatccaatagac agagtcatcgagtttgtgcccacgaaggcgccgtatgaccctcggtggatgctggcaggc cggcctcacccaacccagaaaggtcagtggttgagtggattttttgactacggctctttc tcagagatcatgcaaccgtgggcacagactgtggtggttggcagagccaggctaggagga atacccgtgggagtagttgccgtagaaacccgaacagtggagctgagtatcccggctgat cctgcaaacctggattctgaagccaagattatccagcaggctggccaggtttggttccca gactctgcgtttaagacatatcaggccatcaaggacttcaaccgtgaagggctgcctctg atggtctttgccaactggagaggcttctccggtgggatgaaagatatgtacgaccaagtg ctgaagttcggcgcttacatcgtggatggcttacgggagtgctcgcagcccgtgatggtc tacatccctcctcaggccgagctccgaggtggctcctgggtggtgattgaccccaccatc aacccgcggcacatggaaatgtacgcggaccgggagagcaggggatccgttctggagccg gaagggacagtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtg gacccagtctacatccacttggctgagcgactgggcacccccgagctcagcgcacgcgag cggaaggagctggagagcaagctgaaggagcgggaggagttcctccttcccatctaccac caggtggccgtgcagtttgcggacttgcacgacacccccggccgcatgcaggagaagggg gtcattaatgacatcctggattggaagacttcacgcaccttcttctactggcggctgagg cggctgttgctggaggacctggtcaagaagaaaatccacaacgccaacccggagctgact gatggccagatccaggccatgttaaggcgctggtttgtggaggtggagggaactgtgaag gcctatgtttgggacaacaacaaggatctggtggagtggctggagaaacagctcacagag gaggacggtgtccgctcggtgatcgaggaaaacatcaagtacatcagcagagactacgtc ctcaagcagatccgcagcttggtccaggccaacccggaggtcgccatggattccatcgtc cacatgacacagcacatctcccccacccagcgagcagaagtcgttcgaatcctctcgacg atggactcgccctcaacgtag

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