KEGG   Ovis aries (sheep): 767576
Entry
767576            CDS       T03117                                 
Symbol
CYP11B1
Name
(RefSeq) cytochrome P450 11B1, mitochondrial precursor
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
oas  Ovis aries (sheep)
Pathway
oas00140  Steroid hormone biosynthesis
oas01100  Metabolic pathways
oas04927  Cortisol synthesis and secretion
oas04934  Cushing syndrome
Module
oas_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    767576 (CYP11B1)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    767576 (CYP11B1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    767576 (CYP11B1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:oas00199]
    767576 (CYP11B1)
Enzymes [BR:oas01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     767576 (CYP11B1)
Cytochrome P450 [BR:oas00199]
 Cytochrome P450, animal type
  CYP11 family
   767576 (CYP11B1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 767576
NCBI-ProteinID: NP_001068568
EnsemblRapid: ENSOARG00020013254
UniProt: P51663
LinkDB
Position
9:complement(14477140..14485010)
AA seq 503 aa
MALWAKARVWMAGPWLSLHRARPLGTRASAAPKAVLPFEAMPRCPGNKWMRVLQIWKEQG
SENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVESLQQAESLHPQRMLLEPWLAYR
QARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNA
RGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMFKSTVQLMFV
PRRLSRWTSSSMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMT
LDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQALRQESLVAEARISENPQRATT
ELPLLRAALKETLRLYPVGITLERQVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARP
ESYHPQRWLDRQGSGSRFPHLAFGFGMRQCLGRRVAEVEMLLLLHHVLKNFLVETLAQED
IKMVYRFILMPSTLPLFTFGAIQ
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggcgctgtgggcaaaggccagggtgtggatggcagggccctggctgtctctgcacagg
gcacgcccactgggcaccagagcctctgcagcccccaaggcggtgctgcccttcgaagcc
atgccccggtgtcctggcaacaagtggatgcgggtgctgcagatctggaaggagcagggc
tctgagaacatgcacttggacatgcatcagaccttccaggagctggggcccattttcagg
tacgacgtgggagggagacacatggtgttcgtgatgctgcccgaggatgtggagagcctg
cagcaggcggagagccttcacccccagcggatgctcctggagccctggctggcctaccga
caggctcgcgggcacaagtgtggcgtgttcttgctcaacgggccccagtggcgtttggac
cgactgcggctgaacccagacgtgctctcgctgccagccctgcagaagtacacgcccttg
gtggatggcgtggccagggacttctcccagaccctgaaggcaagggtgctgcagaatgct
cgggggagtctgaccctggacatcgcgcccagcgtcttccgctacaccatcgaagccagc
accttagtcctttacggagagcggcttggccttctgacccagcaaccaaaccctgacagc
ctgaactttatccacgcgctggaggccatgttcaagtccaccgtgcagctcatgtttgtg
ccccggcgcctgtcacggtggacgagcagcagcatgtggagggagcattttgaggcctgg
gactacatcttccagtatgccaacagagccatccagagaatctatcaggagctggccctc
ggccacccgtggcactacagtggcatcgtggcagagctgctgatgcgagcagacatgacc
ctggataccatcaaggccaacacaatcgacctcactgctgggagtgtggacacgacagcc
ttccccttgctgatgactctctttgagctggctcggaacccggaggtgcagcaggccctg
cgccaggagagcctggtggctgaggcccggatctcagaaaatccccagagggccaccacg
gagctgcctttgttgcgggcggccctcaaggagaccttgaggctctatcccgtgggtatc
actttggagcgacaagtgagctcggacctggtgctgcagaactaccacatcccggccggg
acgctggtgaaggtcctactctattccctgggtcgaaaccccgctgtgttcgccagaccc
gagagctatcacccccagcgctggctggaccgccagggctctggaagcaggttcccgcac
ctggcctttggctttggcatgcgccagtgcctggggcggcgtgtggccgaggtggagatg
ctgctgcttctgcaccatgtgctgaagaacttcctggtggagacattggcacaagaggac
ataaagatggtctaccgcttcatactgatgccctctaccctccccctcttcaccttcggg
gccatccagtag

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